2023
1180-P: Impact of Diabetes Exposure In Utero on Mesenchymal Stem Cell Phenotype and Metabolic Function
HAN LEE W, REDLING D, BROOKS O, TEAGUE A, JIANG S, TRYGGESTAD J. 1180-P: Impact of Diabetes Exposure In Utero on Mesenchymal Stem Cell Phenotype and Metabolic Function. Diabetes 2023, 72 DOI: 10.2337/db23-1180-p.Peer-Reviewed Original ResearchControl MSCsExposure to diabetesUmbilical cord Wharton's jellyStem cell phenotypeAbsence of CD34Fetal programming eventsIsotype-control antibodyPresence of CD105Maximal respirationMesenchymal stem cell phenotypeCapacity of MSCsDiabetes exposureCharacteristics of MSCsFetal tissuesUteroWharton's jellyDiabetic milieuExposure to DMCell phenotypeMSC abilityPassage 4Adipogenic capacityEnergy expenditureMetabolic characteristicsCD13
2016
Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA.
Tryggestad J, Vishwanath A, Jiang S, Mallappa A, Teague A, Takahashi Y, Thompson D, Chernausek S. Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. Clinical Science 2016, 130: 1955-67. PMID: 27562513, PMCID: PMC5516927, DOI: 10.1042/cs20160305.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusMiR-130bMiR-let-7a-5pMiR-148aLevel of miR-130bHuman umbilical vein endothelial cellsMiR-148a-3pMiR-30c-5pMiR-148a mimicsInfants of womenMiR-130b-3pMiRNA expressionMiR-452MiR-126Influence of gestational diabetes mellitusDiabetes mellitusTarget protein expressionProtein expressionTarget protein abundanceMiRNAsMonths of ageUmbilical vein endothelial cellsMiRNA speciesQuantitative PCRFetal tissues