2007
Serotonin transporter binding after recovery from eating disorders
Bailer U, Frank G, Henry S, Price J, Meltzer C, Becker C, Ziolko S, Mathis C, Wagner A, Barbarich-Marsteller N, Putnam K, Kaye W. Serotonin transporter binding after recovery from eating disorders. Psychopharmacology 2007, 195: 315-324. PMID: 17690869, DOI: 10.1007/s00213-007-0896-7.Peer-Reviewed Original ResearchConceptsAnorexia nervosaBulimia nervosaControl womenMethodsPositron emission tomographyHealthy control womenRestricting-type anorexia nervosaRationaleSeveral linesDorsal rapheDistribution volume valuesBP valuesFunction persistEmission tomographyDisorder subjectsResultsAfter correctionMultiple comparisonsTracer kinetic modelNervosaSpecific bindingAffective regulation
2006
Personality traits after recovery from eating disorders: Do subtypes differ?
Wagner A, Barbarich‐Marsteller N, Frank G, Bailer U, Wonderlich S, Crosby R, Henry S, Vogel V, Plotnicov K, McConaha C, Kaye W. Personality traits after recovery from eating disorders: Do subtypes differ? International Journal Of Eating Disorders 2006, 39: 276-284. PMID: 16528697, DOI: 10.1002/eat.20251.Peer-Reviewed Original ResearchConceptsBulimia nervosaPersonality traitsState-Trait Anxiety InventoryLatent profile analysisYale-Brown Obsessive Compulsive ScaleEating Disorder ScaleCornell Eating Disorder ScaleSpielberger State-Trait Anxiety InventorySubtypes of EDObsessive Compulsive ScaleCluster B personality disordersPersonality variablesStructured Clinical InterviewB personality disordersBeck Depression InventoryCharacter InventoryAnxiety InventoryYale-BrownDisorder subtypesDisorder ScaleCompulsive ScaleClinical InterviewDepression InventoryPersonality disorderSimilar scores
2005
Normal Brain Tissue Volumes after Long-Term Recovery in Anorexia and Bulimia Nervosa
Wagner A, Greer P, Bailer U, Frank G, Henry S, Putnam K, Meltzer C, Ziolko S, Hoge J, McConaha C, Kaye W. Normal Brain Tissue Volumes after Long-Term Recovery in Anorexia and Bulimia Nervosa. Biological Psychiatry 2005, 59: 291-293. PMID: 16139807, DOI: 10.1016/j.biopsych.2005.06.014.Peer-Reviewed Original ResearchConceptsWhite matter volumeCerebrospinal fluid volumeControl womenBulimia nervosaLong-term recoveryMatter volumeNormal brain tissue volumeFluid volumeStructural brain abnormalitiesHealthy control womenBrain tissue volumesMagnetic resonance imagingBN subgroupsBrain abnormalitiesAnorexiaResonance imagingBinge/Type anorexiaTissue volumeNervosaWomenDisordersBrain imaging of serotonin after recovery from anorexia and bulimia nervosa
Kaye W, Bailer U, Frank G, Wagner A, Henry S. Brain imaging of serotonin after recovery from anorexia and bulimia nervosa. Physiology & Behavior 2005, 86: 15-17. PMID: 16102788, DOI: 10.1016/j.physbeh.2005.06.019.Peer-Reviewed Original ResearchConceptsBulimia nervosaPositron emission tomographyAnorexia nervosaReceptor functionModulation of feedingAge of onsetDegree of efficacyHomogenous presentationSerotonin pathwayGender distributionEmission tomographyBody image distortionBrain functionNew pharmacologyBrain imagingParietal regionsNervosaFood consumptionLines of evidenceSymptomsIllnessAlterationsPsychotherapy approachesPathwayFeeding behaviorSerotonin alterations in anorexia and bulimia nervosa: New insights from imaging studies
Kaye W, Frank G, Bailer U, Henry S, Meltzer C, Price J, Mathis C, Wagner A. Serotonin alterations in anorexia and bulimia nervosa: New insights from imaging studies. Physiology & Behavior 2005, 85: 73-81. PMID: 15869768, DOI: 10.1016/j.physbeh.2005.04.013.Peer-Reviewed Original ResearchConceptsBulimia nervosaAnorexia nervosaBody image distortionAge of onsetParietal cortical regionsHomogenous presentationSerotonin alterationsLimbic structuresSerotonin pathwayGender distributionCortical regionsBrain functionNew pharmacologyNervosaFood consumptionIllnessSymptomsRecent brainAlterationsRecent studiesPsychotherapy approachesBehavioral inhibitionAnxietyFeeding behaviorHedonic aspects
2004
Neuroimaging Studies in Eating Disorders
Frank G, Bailer U, Henry S, Wagner A, Kaye W. Neuroimaging Studies in Eating Disorders. CNS Spectrums 2004, 9: 539-549. PMID: 15208513, DOI: 10.1017/s1092852900009639.Peer-Reviewed Original ResearchConceptsMagnet resonance spectroscopyBulimia nervosaWhite matter volume lossBody image distortionRegional cerebral blood flowCerebral glucose metabolismCerebral blood flowSimilar brain regionsSerotonin metabolismBrain phospholipidsBlood flowGlucose metabolismBrain pathwaysAnorexiaBrain regionsIll stateAppetitive behaviorNeuroimaging studiesParietal regionsEating DisordersDisordersVolume lossSuch studiesMost studiesMetabolismAltered 5-HT2A Receptor Binding after Recovery from Bulimia-Type Anorexia Nervosa: Relationships to Harm Avoidance and Drive for Thinness
Bailer U, Price J, Meltzer C, Mathis C, Frank G, Weissfeld L, McConaha C, Henry S, Brooks-Achenbach S, Barbarich N, Kaye W. Altered 5-HT2A Receptor Binding after Recovery from Bulimia-Type Anorexia Nervosa: Relationships to Harm Avoidance and Drive for Thinness. Neuropsychopharmacology 2004, 29: 1143-1155. PMID: 15054474, PMCID: PMC4301578, DOI: 10.1038/sj.npp.1300430.Peer-Reviewed Original ResearchConceptsControl womenAnorexia nervosaPositron emission tomographyBulimia nervosaBrain serotonin 2A (5-HT(2A)) receptorsMajor depressive disorder diagnosisDisturbances of appetiteLeft subgenual cingulateHealthy control womenDepressive disorder diagnosisEffects of malnutritionSerotonin 2A receptorRight occipital cortexLeft parietal cortexSubgenual cingulate regionsAN-BNReceptor antagonistNeuronal pathwaysSubgenual cingulateOccipital cortexHigh incidenceCingulate regionsParietal cortexCortical regionsEmission tomography