Altered 5-HT2A Receptor Binding after Recovery from Bulimia-Type Anorexia Nervosa: Relationships to Harm Avoidance and Drive for Thinness
Bailer U, Price J, Meltzer C, Mathis C, Frank G, Weissfeld L, McConaha C, Henry S, Brooks-Achenbach S, Barbarich N, Kaye W. Altered 5-HT2A Receptor Binding after Recovery from Bulimia-Type Anorexia Nervosa: Relationships to Harm Avoidance and Drive for Thinness. Neuropsychopharmacology 2004, 29: 1143-1155. PMID: 15054474, PMCID: PMC4301578, DOI: 10.1038/sj.npp.1300430.Peer-Reviewed Original ResearchConceptsControl womenAnorexia nervosaPositron emission tomographyBulimia nervosaBrain serotonin 2A (5-HT(2A)) receptorsMajor depressive disorder diagnosisDisturbances of appetiteLeft subgenual cingulateHealthy control womenDepressive disorder diagnosisEffects of malnutritionSerotonin 2A receptorRight occipital cortexLeft parietal cortexSubgenual cingulate regionsAN-BNReceptor antagonistNeuronal pathwaysSubgenual cingulateOccipital cortexHigh incidenceCingulate regionsParietal cortexCortical regionsEmission tomography