2008
The Placental Syncytium and the Pathophysiology of Preeclampsia and Intrauterine Growth Restriction
Guller S, Y. Y, Fu H, Krikun G, Abrahams VM, Mor G. The Placental Syncytium and the Pathophysiology of Preeclampsia and Intrauterine Growth Restriction. Annals Of The New York Academy Of Sciences 2008, 1127: 129-133. PMID: 18443340, PMCID: PMC3671376, DOI: 10.1196/annals.1434.015.Peer-Reviewed Original ResearchConceptsIntrauterine growth restrictionPathophysiology of preeclampsiaGrowth restrictionPlacental syncytiumFms-like tyrosine kinase-1Complications of pregnancyPlasminogen activator inhibitor-1Tyrosine kinase-1Activator inhibitor-1Release of factorsPlacental damageSoluble endoglinEndothelium dysfunctionLaser capture microdissectionMaternal bloodAntiangiogenic factorsPreeclampsiaFas ligandWestern blottingInhibitor-1Reactive oxygen speciesCapture microdissectionPregnancyPathophysiologyKinase 1
2005
Alterations in Syncytiotrophoblast Cytokine Expression Following Treatment with Lipopolysaccharide
Ma Y, Mor G, Abrahams VM, Buhimschi IA, Buhimschi CS, Guller S. Alterations in Syncytiotrophoblast Cytokine Expression Following Treatment with Lipopolysaccharide. American Journal Of Reproductive Immunology 2005, 55: 12-18. PMID: 16364007, DOI: 10.1111/j.1600-0897.2005.00347.x.Peer-Reviewed Original ResearchConceptsCytokine expressionLPS treatmentInflammatory compoundsAnti-inflammatory cytokinesIL-8 levelsInterleukin-8 levelsAnti-inflammatory compoundsEnzyme-linked immunosorbent assayCell typesCytokine levelsGlucocorticoid treatmentMaternal bloodDEX treatmentPlacental syncytiumSyncytiotrophoblastImmunosorbent assayLPSPrimary culturesTreatmentCytokinesFourfold increaseExpressionSyncytiaGestationLevels