2011
Isolation of Hofbauer Cells from Human Term Placentas with High Yield and Purity
Tang Z, Tadesse S, Norwitz E, Mor G, Abrahams VM, Guller S. Isolation of Hofbauer Cells from Human Term Placentas with High Yield and Purity. American Journal Of Reproductive Immunology 2011, 66: 336-348. PMID: 21545365, PMCID: PMC3154981, DOI: 10.1111/j.1600-0897.2011.01006.x.Peer-Reviewed Original ResearchConceptsHofbauer cellsHuman term placentaTerm placentaComplications of pregnancyCell typesMacrophage functionPhagocytotic activityFlow cytometryVillus functionConsensus methodologyVacuolated appearancePhagocytosis assaysPlacentaPercoll gradientCTFuture studiesFibroblastsHBCCellsDaysHigh levelsComplicationsCulture mediumPregnancyMacrophagesPlacental Hofbauer cells and complications of pregnancy
Tang Z, Abrahams VM, Mor G, Guller S. Placental Hofbauer cells and complications of pregnancy. Annals Of The New York Academy Of Sciences 2011, 1221: 103-108. PMID: 21401637, PMCID: PMC3707113, DOI: 10.1111/j.1749-6632.2010.05932.x.Peer-Reviewed Original ResearchConceptsComplications of pregnancyHofbauer cellsHistological chorioamnionitisCytokine-mediated inflammationPlacental Hofbauer cellsPlacental pathophysiologyPlacental macrophagesUnknown etiologyPlacental functionMajor cell typesVillus functionComplicationsPregnancyCell typesSpecific roleGene expressionChorioamnionitisVillitisCellsInflammationGestationPathophysiologyEtiologyPlacentaMacrophages
2008
The Placental Syncytium and the Pathophysiology of Preeclampsia and Intrauterine Growth Restriction
Guller S, Y. Y, Fu H, Krikun G, Abrahams VM, Mor G. The Placental Syncytium and the Pathophysiology of Preeclampsia and Intrauterine Growth Restriction. Annals Of The New York Academy Of Sciences 2008, 1127: 129-133. PMID: 18443340, PMCID: PMC3671376, DOI: 10.1196/annals.1434.015.Peer-Reviewed Original ResearchConceptsIntrauterine growth restrictionPathophysiology of preeclampsiaGrowth restrictionPlacental syncytiumFms-like tyrosine kinase-1Complications of pregnancyPlasminogen activator inhibitor-1Tyrosine kinase-1Activator inhibitor-1Release of factorsPlacental damageSoluble endoglinEndothelium dysfunctionLaser capture microdissectionMaternal bloodAntiangiogenic factorsPreeclampsiaFas ligandWestern blottingInhibitor-1Reactive oxygen speciesCapture microdissectionPregnancyPathophysiologyKinase 1