R‐CHOP versus dose‐adjusted R‐EPOCH in frontline management of primary mediastinal B‐cell lymphoma: a multi‐centre analysis
Shah NN, Szabo A, Huntington SF, Epperla N, Reddy N, Ganguly S, Vose J, Obiozor C, Faruqi F, Kovach AE, Costa LJ, Xavier AC, Okal R, Kanate AS, Ghosh N, Kharfan‐Dabaja M, Strelec L, Hamadani M, Fenske TS, Calzada O, Cohen JB, Chavez J, Svoboda J. R‐CHOP versus dose‐adjusted R‐EPOCH in frontline management of primary mediastinal B‐cell lymphoma: a multi‐centre analysis. British Journal Of Haematology 2017, 180: 534-544. PMID: 29265182, DOI: 10.1111/bjh.15051.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntibodies, Monoclonal, Murine-DerivedAntineoplastic Combined Chemotherapy ProtocolsCombined Modality TherapyCyclophosphamideDisease ManagementDoxorubicinEtoposideFemaleHumansLymphoma, B-CellMaleMediastinal NeoplasmsMiddle AgedNeoplasm GradingNeoplasm StagingPrednisoneRecurrenceRetrospective StudiesRituximabTreatment FailureTreatment OutcomeVincristineYoung AdultConceptsPrimary mediastinal large B-cell lymphomaDA-R-EPOCHDose-adjusted R-EPOCHNon-Hodgkin lymphomaB-cell lymphomaR-CHOPR-EPOCHMediastinal large B-cell lymphomaPrimary mediastinal B-cell lymphomaLarge B-cell lymphomaR-CHOP patientsComplete response rateMediastinal B-cell lymphomaTreatment-related complicationsPhase II trialProgression-free survivalR-CHOP chemotherapyTreatment-related toxicityUnique clinicopathological featuresMulti-center analysisII trialOverall survivalSecondary outcomesPrimary outcomeClinicopathological features