Real-World IgG Testing Frequency and Characteristics Associated with Hypogammaglobulinemia after Anti-CD20 Exposure in Patients with Chronic Lymphocytic Leukemia (CLL)
Hooley I, Maignan K, Jacob A, Medina A, Benderoff L, Chen R, Huntington S. Real-World IgG Testing Frequency and Characteristics Associated with Hypogammaglobulinemia after Anti-CD20 Exposure in Patients with Chronic Lymphocytic Leukemia (CLL). Blood 2020, 136: 43-44. DOI: 10.1182/blood-2020-137094.Peer-Reviewed Original ResearchChronic lymphocytic leukemiaCurrent equity holderIgG testCD20 mAbsBaseline characteristicsIgG levelsSevere hypogammaglobulinemiaHigher likelihoodCD20 monoclonal antibody therapyLogistic regressionUnknown statusAnti-CD20 therapyFirst-line settingClinical baseline characteristicsReal-world cohortSimilar baseline characteristicsMonoclonal antibody therapyPotential adverse eventsHypothesis-generating studyDe-identified databaseCurrent employmentCD20 administrationCD20 therapyConcurrent chemotherapyIgG testing