2024
Rheumatoid arthritis and peripartum cardiovascular complications: focusing on non-traditional cardiovascular risk factors to improve maternal outcomes
Goldstein S, Lindley K. Rheumatoid arthritis and peripartum cardiovascular complications: focusing on non-traditional cardiovascular risk factors to improve maternal outcomes. European Heart Journal 2024, 45: 1537-1539. PMID: 38713839, DOI: 10.1093/eurheartj/ehae164.Peer-Reviewed Original ResearchConceptsCardiovascular risk factorsMaternal cardiovascular risk factorsPre-conception counsellingNon-traditional cardiovascular risk factorsCardio-obstetricsAdverse pregnancy outcomesRisk factorsPregnancy outcomesCardiovascular adverse outcomesAdverse outcomesMaternal outcomesRheumatoid arthritisMaternal cardiovascular complicationsCardiovascular complicationsCounselingOutcomesPregnancyRiskArthritisPracticeFactors
2023
Utilization and Outcomes of Primary Prevention Implantable Cardioverter‐Defibrillators in Patients With Hypertrophic Cardiomyopathy
Goldstein S, Kennedy K, Friedman D, Al‐Khatib S, Wang A. Utilization and Outcomes of Primary Prevention Implantable Cardioverter‐Defibrillators in Patients With Hypertrophic Cardiomyopathy. Journal Of The American Heart Association 2023, 12: e029293. PMID: 37586066, PMCID: PMC10492935, DOI: 10.1161/jaha.122.029293.Peer-Reviewed Original ResearchConceptsNew York Heart Association classPrimary prevention implantable cardioverter-defibrillatorHistory of nonsustained ventricular tachycardiaImplantable cardioverter-defibrillatorImplantable cardioverter-defibrillator utilizationNonsustained ventricular tachycardiaHypertrophic cardiomyopathyAssociation classVentricular tachycardiaOlder patientsCardioverter-defibrillatorLeft ventricular ejection fractionRisk factorsNational Cardiovascular Data Registry ICD RegistryFactors associated with mortalityImplantable cardioverter-defibrillator implantationAssociated with postdischarge mortalityVentricular ejection fractionPrevalence of risk factorsSudden cardiac deathPostdischarge hospitalizationAssociated with hospitalizationCenters for MedicareEjection fractionICD Registry
2022
Risk Factors and Outcomes Associated With Hypertensive Disorders of Pregnancy in Maternal Congenital Heart Disease
Goldstein S, Savu A, Islam S, Ward C, Krasuski R, Grotegut C, Newby L, Hornberger L, Windram J, Kaul P. Risk Factors and Outcomes Associated With Hypertensive Disorders of Pregnancy in Maternal Congenital Heart Disease. JACC Advances 2022, 1: 100036. PMID: 38939317, PMCID: PMC11198567, DOI: 10.1016/j.jacadv.2022.100036.Peer-Reviewed Original ResearchCongenital heart diseaseAssociation of HDPRisk factorsAdverse eventsAdverse outcomesCongenital heart disease lesionsHypertensive disorders of pregnancyPresence of HDPGestational age infantsDisorders of pregnancyAssociated with HDPPrevalence of HDPAssociated with increased riskRetrospective cohort studyDisease backgroundAssociated with certain adverse outcomesDelivery admissionPreterm deliveryHypertensive disordersChronic hypertensionAge infantsLive birthsMaternal characteristicsDiabetes mellitusStrength of association
2020
Sex differences in left ventricular electrical dyssynchrony and outcomes with cardiac resynchronization therapy
Friedman D, Emerek K, Sørensen P, Zeitler E, Goldstein S, Al-Khatib S, Søgaard P, Graff C, Atwater B. Sex differences in left ventricular electrical dyssynchrony and outcomes with cardiac resynchronization therapy. Heart Rhythm O2 2020, 1: 243-249. PMID: 34113878, PMCID: PMC8183970, DOI: 10.1016/j.hroo.2020.07.004.Peer-Reviewed Original ResearchLeft bundle branch blockCardiac resynchronization therapyElectrical dyssynchronyQRS areaHigher burden of risk factorsLV assist device implantationAssociated with better long-term outcomesQRS characteristicsCardiac resynchronization therapy benefitsBurden of risk factorsCox regression analysisLong-term outcomesBundle branch blockAssist device implantationLV dyssynchronyCardiac transplantationResynchronization therapyBranch blockDevice implantationDyssynchronyFemale sexQRSdRisk factorsElectrophysiological explanationMorphological assessmentCauses of Death and Cardiovascular Comorbidities in Adults With Congenital Heart Disease
Goldstein S, D’Ottavio A, Spears T, Chiswell K, Hartman R, Krasuski R, Kemper A, Meyer R, Hoffman T, Walsh M, Sang C, Paolillo J, Li J. Causes of Death and Cardiovascular Comorbidities in Adults With Congenital Heart Disease. Journal Of The American Heart Association 2020, 9: e016400. PMID: 32654582, PMCID: PMC7660712, DOI: 10.1161/jaha.119.016400.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseSevere congenital heart diseaseMedian ageNonsevere CHDPresence of cardiovascular comorbiditiesHeart diseaseCardiovascular risk factorsNon-CHD causesIschemic heart diseaseElectronic medical record dataDeath certificate dataCause of deathNonsevere diseaseContemporary cohortValvular lesionsCardiovascular comorbidityCardiovascular comorbiditiesResults PatientsCardiovascular deathMedical record dataRisk factorsSevere groupLesion severityPatientsCertificate data
2015
Does This Patient With Chest Pain Have Acute Coronary Syndrome?: The Rational Clinical Examination Systematic Review
Fanaroff A, Rymer J, Goldstein S, Simel D, Newby L. Does This Patient With Chest Pain Have Acute Coronary Syndrome?: The Rational Clinical Examination Systematic Review. JAMA 2015, 314: 1955-1965. PMID: 26547467, DOI: 10.1001/jama.2015.12735.Peer-Reviewed Original ResearchConceptsDiagnosis of acute coronary syndromeAcute coronary syndromeHigh-risk rangeRisk scoreProspective study of diagnostic test accuracyHEART scoreEmergency departmentChest painCardiac Society of AustraliaProbability of acute coronary syndromeTIMI scoreStudies of diagnostic test accuracyCoronary syndromePhysical examinationRisk factorsDiagnosing ACSLikelihood ratioSuspected acute coronary syndromeAcute chest painAbnormal stress testLow-risk patientsHigh-risk patientsTIMI risk scoreCardiac-specific troponinEvidence of ischemia