2024
Complex Congenital Heart Disease in the Adult
Goldstein S, Krasuski R. Complex Congenital Heart Disease in the Adult. Annual Review Of Medicine 2024, 75: 493-512. PMID: 38285514, DOI: 10.1146/annurev-med-050922-052324.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseAdult congenital heart diseaseComplex congenital heart diseaseHeart diseaseSevere birth defectsStructural abnormalitiesBirth defectsComplex lesionsFrequent causeHigh riskImprove outcomesPediatric outcomesHeterogeneous groupPalliative interventionsCardiovascular systemDiseaseAdultsOutcomesComplications
2022
Risk Factors and Outcomes Associated With Hypertensive Disorders of Pregnancy in Maternal Congenital Heart Disease
Goldstein S, Savu A, Islam S, Ward C, Krasuski R, Grotegut C, Newby L, Hornberger L, Windram J, Kaul P. Risk Factors and Outcomes Associated With Hypertensive Disorders of Pregnancy in Maternal Congenital Heart Disease. JACC Advances 2022, 1: 100036. PMID: 38939317, PMCID: PMC11198567, DOI: 10.1016/j.jacadv.2022.100036.Peer-Reviewed Original ResearchCongenital heart diseaseAssociation of HDPRisk factorsAdverse eventsAdverse outcomesCongenital heart disease lesionsHypertensive disorders of pregnancyPresence of HDPGestational age infantsDisorders of pregnancyAssociated with HDPPrevalence of HDPAssociated with increased riskRetrospective cohort studyDisease backgroundAssociated with certain adverse outcomesDelivery admissionPreterm deliveryHypertensive disordersChronic hypertensionAge infantsLive birthsMaternal characteristicsDiabetes mellitusStrength of associationPulmonary Hypertension in Adults with Congenital Heart Disease
Goldstein S, Krasuski R. Pulmonary Hypertension in Adults with Congenital Heart Disease. Cardiology Clinics 2022, 40: 55-67. PMID: 34809917, DOI: 10.1016/j.ccl.2021.08.006.Peer-Reviewed Original ResearchConceptsPAH-CHDPulmonary arterial hypertension related to congenital heart diseaseSystemic-to-pulmonary shuntAssociated with significant morbidityCongenital heart diseasePulmonary vascular resistancePulmonary vascular remodelingShunt reversalEisenmenger syndromePulmonary hypertensionCentral cyanosisPrimary management strategySignificant morbidityMedical therapySevere elevationVascular resistanceDefect closureSevere phenotypeVascular remodelingHeart diseasePathological processesShuntCyanosisAdultsHypoxemia
2021
AGE AND LOCATION OF DEATH DIFFER IN ADULT PATIENTS WITH CONGENITAL HEART DISEASE COMPARED WITH THE GENERAL POPULATION
Goldstein S, Kumar P, Shahid I, Serfas J, Krasuski M, Khan M, Krasuski R. AGE AND LOCATION OF DEATH DIFFER IN ADULT PATIENTS WITH CONGENITAL HEART DISEASE COMPARED WITH THE GENERAL POPULATION. Journal Of The American College Of Cardiology 2021, 77: 489. DOI: 10.1016/s0735-1097(21)01848-9.Peer-Reviewed Original Research
2020
Causes of Death and Cardiovascular Comorbidities in Adults With Congenital Heart Disease
Goldstein S, D’Ottavio A, Spears T, Chiswell K, Hartman R, Krasuski R, Kemper A, Meyer R, Hoffman T, Walsh M, Sang C, Paolillo J, Li J. Causes of Death and Cardiovascular Comorbidities in Adults With Congenital Heart Disease. Journal Of The American Heart Association 2020, 9: e016400. PMID: 32654582, PMCID: PMC7660712, DOI: 10.1161/jaha.119.016400.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseSevere congenital heart diseaseMedian ageNonsevere CHDPresence of cardiovascular comorbiditiesHeart diseaseCardiovascular risk factorsNon-CHD causesIschemic heart diseaseElectronic medical record dataDeath certificate dataCause of deathNonsevere diseaseContemporary cohortValvular lesionsCardiovascular comorbidityCardiovascular comorbiditiesResults PatientsCardiovascular deathMedical record dataRisk factorsSevere groupLesion severityPatientsCertificate data
2017
The Use of Implantable Cardioverter-defibrillators in the Prevention of Sudden Cardiac Death: A Focus on Congenital Heart Disease and Inherited Arrhythmia Syndromes
Goldstein S, Ward C, Al-Khatib S. The Use of Implantable Cardioverter-defibrillators in the Prevention of Sudden Cardiac Death: A Focus on Congenital Heart Disease and Inherited Arrhythmia Syndromes. Journal Of Innovations In Cardiac Rhythm Management 2017, 9: 2996-3005. PMID: 32494470, PMCID: PMC7252881, DOI: 10.19102/icrm.2018.090103.Peer-Reviewed Original ResearchCongenital heart diseaseInherited arrhythmia syndromesSudden cardiac deathArrhythmia syndromesCardiac deathIncreased risk of sudden cardiac deathPrevention of sudden cardiac deathRisk of sudden cardiac deathHeart diseaseImplantable cardioverter-defibrillator (ICDCardioverter-defibrillator (ICDRisk stratification methodsNon-randomized studiesImplantable cardioverter-defibrillatorRandomized clinical trialsCardioverter-defibrillatorClinical trialsIncreased riskPatientsSyndromeDiseaseImplantationStratification methodICDDeath