2018
Impaired right ventricular reserve predicts adverse cardiac outcomes in adults with congenital right heart disease
Yeh D, Schmidt A, Eisman A, Serfas J, Naqvi M, Youniss M, Ryfa A, Khan A, Safi L, Tabtabai S, Bhatt A, Lewis G. Impaired right ventricular reserve predicts adverse cardiac outcomes in adults with congenital right heart disease. Heart 2018, 104: 2044. PMID: 30030334, DOI: 10.1136/heartjnl-2017-312572.Peer-Reviewed Original ResearchConceptsCardiopulmonary exercise testingRV reserveRight ventricleHeart failureNew York Heart Association classPrimary composite clinical outcomeFirst-pass radionuclide ventriculographyPrevalence of heart failureRV ejection fractionRV systolic functionEvent-free survivalMedian follow-upCongenital heart diseaseReserve groupComposite clinical outcomeAdverse cardiac outcomesTertiary care centreRight ventricular reserveAdverse cardiovascular outcomesPredicting adverse cardiovascular outcomesSystolic function assessmentRV dilatationACHD populationPrognostic impactAsymptomatic patients
2015
Assessing mitral regurgitation in the prediction of clinical outcome after cardiac resynchronization therapy
Upadhyay G, Chatterjee N, Kandala J, Friedman D, Park M, Tabtabai S, Hung J, Singh J. Assessing mitral regurgitation in the prediction of clinical outcome after cardiac resynchronization therapy. Heart Rhythm 2015, 12: 1201-1208. PMID: 25708879, DOI: 10.1016/j.hrthm.2015.02.022.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyDegree of baseline MRMitral regurgitationBaseline MRMR improvementHF hospitalizationClinical outcomesSurface QRSHeart failureAssociated with lower HF hospitalizationsCohort study of patientsImproved ventricular geometryFollow-up echocardiographyPrediction of clinical outcomeReducing mitral regurgitationStudy of patientsAll-cause mortalityPrediction of HFWorsening MRMR severityMedian ageIschemic cardiomyopathyResynchronization therapyImproved survivalMR reduction