2019
Achievement of Target Doses of Guideline-Directed Medical Therapy Prior to Cardiac Resynchronization Therapy is Suboptimal
Balakumaran K, Goldgrab D, Krishnan A, Shah N, Kim M, Rabieihashemi S, Cipriani K, Pickett C, Tabtabai S. Achievement of Target Doses of Guideline-Directed Medical Therapy Prior to Cardiac Resynchronization Therapy is Suboptimal. Journal Of Cardiac Failure 2019, 25: s128. DOI: 10.1016/j.cardfail.2019.07.366.Peer-Reviewed Original ResearchGuideline directed medical therapyCardiac resynchronization therapyCardiac resynchronization therapy implantationHeart failureTarget doseTime of implantationCRT implantationResynchronization therapyMedical therapyDosing of guideline-directed medical therapyGuideline-directed medical therapyDirected medical therapyNYHA class IIIII heart failureDocumented atrial fibrillationProportion of patientsDevice-based treatmentBackground Heart failureBB therapyHF registryIschemic cardiomyopathyClinical characteristicsChart reviewDevice therapyAtrial fibrillation
2015
Assessing mitral regurgitation in the prediction of clinical outcome after cardiac resynchronization therapy
Upadhyay G, Chatterjee N, Kandala J, Friedman D, Park M, Tabtabai S, Hung J, Singh J. Assessing mitral regurgitation in the prediction of clinical outcome after cardiac resynchronization therapy. Heart Rhythm 2015, 12: 1201-1208. PMID: 25708879, DOI: 10.1016/j.hrthm.2015.02.022.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyDegree of baseline MRMitral regurgitationBaseline MRMR improvementHF hospitalizationClinical outcomesSurface QRSHeart failureAssociated with lower HF hospitalizationsCohort study of patientsImproved ventricular geometryFollow-up echocardiographyPrediction of clinical outcomeReducing mitral regurgitationStudy of patientsAll-cause mortalityPrediction of HFWorsening MRMR severityMedian ageIschemic cardiomyopathyResynchronization therapyImproved survivalMR reduction