2023
Understanding the Burden of 30-Day Readmission in Patients With Both Primary and Secondary Diagnoses of Heart Failure: Causes, Timing, and Impact of Co-Morbidities
Kim M, Aseltine R, Tabtabai S. Understanding the Burden of 30-Day Readmission in Patients With Both Primary and Secondary Diagnoses of Heart Failure: Causes, Timing, and Impact of Co-Morbidities. The American Journal Of Cardiology 2023, 210: 76-84. PMID: 37858595, DOI: 10.1016/j.amjcard.2023.09.086.Peer-Reviewed Original ResearchPredictors of 30-Day Readmission in Patients Hospitalized With Heart Failure as a Primary Versus Secondary Diagnosis
Kim M, Tabtabai S, Aseltine R. Predictors of 30-Day Readmission in Patients Hospitalized With Heart Failure as a Primary Versus Secondary Diagnosis. The American Journal Of Cardiology 2023, 207: 407-417. PMID: 37782972, DOI: 10.1016/j.amjcard.2023.08.111.Peer-Reviewed Original ResearchConceptsElixhauser co-morbidity indexHeart failureMultivariate logistic regressionCo-morbiditiesSecondary diagnosisPatients admitted with HFPatient co-morbiditiesAdmitted with HFDetrimental to patientsPopulation of patientsLogistic regressionCo-morbidity indexReadmission riskDiagnosis of HFSecondary diagnosis of HFNationwide Readmissions DatabaseCo-morbid complicationsRenal failureComparing patientsShort-term rehospitalizationHF patientsStatistically significant predictorsPredicting 30-day readmissionIncreased riskElixhauser co-morbiditiesReadmission Patterns In Patients Admitted With Primary Or Secondary Diagnosis Of Heart Failure
Kim M, Aseltine R, Tabtabai S. Readmission Patterns In Patients Admitted With Primary Or Secondary Diagnosis Of Heart Failure. Journal Of Cardiac Failure 2023, 29: 682. DOI: 10.1016/j.cardfail.2022.10.337.Peer-Reviewed Original ResearchSecondary diagnosis of HFDiagnosis of HFSecondary diagnosisPrimary diagnosisRisk of hospital admissionSecondary diagnosis of heart failureReadmission ratesIndex admissionLower household incomePrimary diagnosis of HFComorbid conditionsPercentage of readmissionsEffects of comorbid conditionsHeart failureBackground Heart failurePublic health issueSystolic HFDiastolic HFNational Readmission DatabaseRisk of mortalityReduce HF readmissionsHospital characteristicsDiagnosis of heart failureCost of hospitalizationRisk comorbiditiesThe Presence Of Clinical COPD Predicts Mortality In Heart Failure Patient Population
Adeel M, Wakefield D, Soucier R, ZuWallack R, Tabtabai S. The Presence Of Clinical COPD Predicts Mortality In Heart Failure Patient Population. Journal Of Cardiac Failure 2023, 29: 643. DOI: 10.1016/j.cardfail.2022.10.237.Peer-Reviewed Original ResearchChronic obstructive pulmonary diseaseHFpEF patientsHFrEF patientsHeart failurePrognostic impact of chronic obstructive pulmonary diseaseMedian LOSDiagnosis groupsHF typePresence of chronic obstructive pulmonary diseaseClinical diagnosis of chronic obstructive pulmonary diseaseConcurrent chronic obstructive pulmonary diseaseKaplan-Meier survival curvesComorbid chronic obstructive pulmonary diseaseDiagnosis of chronic obstructive pulmonary diseaseHeart failure patient populationCalcium channel blockersCox regression analysisClinical chronic obstructive pulmonary diseaseIn-hospital mortalityChronic obstructive pulmonary disease diagnosisDiagnosis of HFYears of ageImpact of chronic obstructive pulmonary diseaseObstructive pulmonary diseasePrognostic impactEffect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart Failure
Mentz R, Anstrom K, Eisenstein E, Sapp S, Greene S, Morgan S, Testani J, Harrington A, Sachdev V, Ketema F, Kim D, Desvigne-Nickens P, Pitt B, Velazquez E, Adams K, Bhatt K, DeWald T, Axsom K, Murthy S, Rich J, Testani J, Smith B, Vader J, McCulloch M, Skopicki H, Psotka M, Heroux A, Lala-Trindade A, Stevens G, Tang W, Lev Y, William P, Eberly A, Gottleib S, Haught W, Grafton G, Larned J, Tejwani L, Mody F, Krim S, Robinson M, Fang J, Adler A, Bell A, Banerjee D, Ruiz Duque E, Mizyed A, Rommel J, Arhinful J, Goyal P, Hall M, Hummel S, Shetty S, Haas D, Vilaro J, Alexy T, Herre J, Clark J, Ambrosy A, Gaglianello N, Ramasubbu K, Meadows J, Tabtabai S, Sherwood M, Hasni S, D'Urso M, Muneer B, Dunlap S, Davis W, Friedman D, Guglin M, Ferguson A, Abbate A, Smart F. Effect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart Failure. JAMA 2023, 329: 214-223. PMID: 36648467, PMCID: PMC9857435, DOI: 10.1001/jama.2022.23924.Peer-Reviewed Original ResearchConceptsCause mortalityHeart failureTorsemide groupFurosemide groupTotal hospitalizationsCause hospitalizationEffects of torsemideDiuretic strategyPrespecified subgroupsSecondary outcomesEjection fractionMedian agePrimary outcomeHospitalizationMAIN OUTCOMEPatientsFurosemideMortalityMonthsTorsemidePrimary hypothesisSignificant differencesFinal dateOutcomesTrials
2020
A Dedicated Guideline Directed Medical Therapy Clinic Improves Quality of Care and Outcomes In Patients with Heart Failure and Reduced Ejection Fraction
Tiu J, Balakumaran K, Barry M, Cipriani K, Kearney L, Oranefo J, Kim M, Tabtabai S. A Dedicated Guideline Directed Medical Therapy Clinic Improves Quality of Care and Outcomes In Patients with Heart Failure and Reduced Ejection Fraction. Journal Of Cardiac Failure 2020, 26: s133. DOI: 10.1016/j.cardfail.2020.09.386.Peer-Reviewed Original ResearchTarget doses of beta-blockersProportion of patientsDoses of beta-blockersTarget doseMinnesota Living with Heart Failure QuestionnaireHeart failure parametersEjection fractionHeart failurePHQ-9 scoresBeta-blockersLV end-diastolic diameterAssociated with significant morbidityNYHA class IIEnd-diastolic diameterReduced ejection fractionNon-ischemic cardiomyopathyRegimen of medicationCongestive heart failureMedian PHQ-9 scoreResults of landmark trialsHeart failure diagnosisEnrollment of patientsImproving clinical outcomesHeart Failure QuestionnaireMonths post-intervention
2019
Achievement of Target Doses of Guideline-Directed Medical Therapy Prior to Cardiac Resynchronization Therapy is Suboptimal
Balakumaran K, Goldgrab D, Krishnan A, Shah N, Kim M, Rabieihashemi S, Cipriani K, Pickett C, Tabtabai S. Achievement of Target Doses of Guideline-Directed Medical Therapy Prior to Cardiac Resynchronization Therapy is Suboptimal. Journal Of Cardiac Failure 2019, 25: s128. DOI: 10.1016/j.cardfail.2019.07.366.Peer-Reviewed Original ResearchGuideline directed medical therapyCardiac resynchronization therapyCardiac resynchronization therapy implantationHeart failureTarget doseTime of implantationCRT implantationResynchronization therapyMedical therapyDosing of guideline-directed medical therapyGuideline-directed medical therapyDirected medical therapyNYHA class IIIII heart failureDocumented atrial fibrillationProportion of patientsDevice-based treatmentBackground Heart failureBB therapyHF registryIschemic cardiomyopathyClinical characteristicsChart reviewDevice therapyAtrial fibrillation
2018
Updates in heart failure 30-day readmission prevention
Goldgrab D, Balakumaran K, Kim M, Tabtabai S. Updates in heart failure 30-day readmission prevention. Heart Failure Reviews 2018, 24: 177-187. PMID: 30488242, DOI: 10.1007/s10741-018-9754-4.Peer-Reviewed Original ResearchConceptsHospital Readmissions Reduction ProgramAffordable Care ActReduce health care costsReadmission ratesReduce short-term readmissionsReadmissions Reduction ProgramHF readmissionHealth care costsCare costsShort-term readmissionCare ActAdmission diagnosisPrevent heart failureReduction programsRemote hemodynamic monitoringReadmissionMedical therapyHeart failureHF patientsHemodynamic monitoringHospitalProgramImpaired right ventricular reserve predicts adverse cardiac outcomes in adults with congenital right heart disease
Yeh D, Schmidt A, Eisman A, Serfas J, Naqvi M, Youniss M, Ryfa A, Khan A, Safi L, Tabtabai S, Bhatt A, Lewis G. Impaired right ventricular reserve predicts adverse cardiac outcomes in adults with congenital right heart disease. Heart 2018, 104: 2044. PMID: 30030334, DOI: 10.1136/heartjnl-2017-312572.Peer-Reviewed Original ResearchConceptsCardiopulmonary exercise testingRV reserveRight ventricleHeart failureNew York Heart Association classPrimary composite clinical outcomeFirst-pass radionuclide ventriculographyPrevalence of heart failureRV ejection fractionRV systolic functionEvent-free survivalMedian follow-upCongenital heart diseaseReserve groupComposite clinical outcomeAdverse cardiac outcomesTertiary care centreRight ventricular reserveAdverse cardiovascular outcomesPredicting adverse cardiovascular outcomesSystolic function assessmentRV dilatationACHD populationPrognostic impactAsymptomatic patients
2017
Acoustic speech analysis of patients with decompensated heart failure: A pilot study
Murton O, Daher M, Cunningham T, Verkouw K, Tabtabai S, Steiner J, Hillman R, Dec G, Ausiello D, Mehta D. Acoustic speech analysis of patients with decompensated heart failure: A pilot study. The Journal Of The Acoustical Society Of America 2017, 142: 2639-2640. DOI: 10.1121/1.5014673.Peer-Reviewed Original ResearchHeart failureIntracardiac filling pressuresDecompensated heart failureImpaired cardiac functionMean length of stayAverage weight lossLength of stayPeripheral edemaCardiac functionPrevent decompensationFilling pressurePatientsDecompensationMonitoring patientsEdemaWeight lossMean lengthInpatient treatmentEarly indicatorPilot studyChronic conditionsAcoustic speech analysisTreatmentAcoustic speech analysis of patients with decompensated heart failure: A pilot study
Murton O, Hillman R, Mehta D, Semigran M, Daher M, Cunningham T, Verkouw K, Tabtabai S, Steiner J, Dec G, Ausiello D. Acoustic speech analysis of patients with decompensated heart failure: A pilot study. The Journal Of The Acoustical Society Of America 2017, 142: el401-el407. PMID: 29092550, PMCID: PMC5724620, DOI: 10.1121/1.5007092.Peer-Reviewed Original ResearchConceptsHeart failureIntracardiac filling pressuresDecompensated heart failureSpeech analysisIndicators of HFAcoustic speech analysisSpeech breathing characteristicsDiuretic treatmentPeripheral edemaPilot studyFilling pressureCreaky voiceSpeech passagesPatientsMonitoring patientsSpeech respirationSpeechIncreasing fundamental frequencyEdemaSustained vowelsAcoustic measurements
2016
National Trends in Hospitalizations of Adults With Tetralogy of Fallot
Schmidt A, Yeh D, Tabtabai S, Kennedy K, Yeh R, Bhatt A. National Trends in Hospitalizations of Adults With Tetralogy of Fallot. The American Journal Of Cardiology 2016, 118: 906-911. PMID: 27530825, PMCID: PMC5349299, DOI: 10.1016/j.amjcard.2016.06.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultArrhythmias, CardiacComorbidityCross-Sectional StudiesDatabases, FactualDiabetes MellitusEquipment FailureFemaleHeart FailureHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHospitalizationHumansHypertensionKidney DiseasesMaleMiddle AgedObesityPneumoniaPrevalencePulmonary ValveTetralogy of FallotUnited StatesYoung AdultConceptsTetralogy of FallotHigher quality of careCo-morbiditiesQuality of careFollow-up of patientsHealth care systemPrevalence of obesityModifiable risk factorsPrevalence of co-morbiditiesRates of co-morbiditiesUnited States Nationwide Inpatient SamplePulmonic valve replacementPrimary admission diagnosisHospitalizations of adultsPopulation of adultsNationwide Inpatient SampleCross-sectional dataCare systemDiagnostic codesValve replacementPrevention effortsHeart failureHospital admissionAdmission diagnosisFollow-up
2015
National Trends in Hospitalizations for Patients With Single-Ventricle Anatomy
Tabtabai S, Yeh D, Stefanescu A, Kennedy K, Yeh R, Bhatt A. National Trends in Hospitalizations for Patients With Single-Ventricle Anatomy. The American Journal Of Cardiology 2015, 116: 773-778. PMID: 26100589, DOI: 10.1016/j.amjcard.2015.05.053.Peer-Reviewed Original ResearchConceptsMedical co-morbiditiesSingle-ventricleHeart failureManagement of HFCo-morbiditiesCost of careSV anatomyAdult hospitalsCohort of patientsNationwide Inpatient SampleLength of stayIncreased cost of careReduce costs of careAnatomy patientsInternational Classification of DiseasesAtrial arrhythmiasCoexisting hypertensionRenal diseaseInhospital mortalityLiver diseaseClassification of DiseasesPatientsImprove outcomesInpatient SampleYounger ageAssessing mitral regurgitation in the prediction of clinical outcome after cardiac resynchronization therapy
Upadhyay G, Chatterjee N, Kandala J, Friedman D, Park M, Tabtabai S, Hung J, Singh J. Assessing mitral regurgitation in the prediction of clinical outcome after cardiac resynchronization therapy. Heart Rhythm 2015, 12: 1201-1208. PMID: 25708879, DOI: 10.1016/j.hrthm.2015.02.022.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyDegree of baseline MRMitral regurgitationBaseline MRMR improvementHF hospitalizationClinical outcomesSurface QRSHeart failureAssociated with lower HF hospitalizationsCohort study of patientsImproved ventricular geometryFollow-up echocardiographyPrediction of clinical outcomeReducing mitral regurgitationStudy of patientsAll-cause mortalityPrediction of HFWorsening MRMR severityMedian ageIschemic cardiomyopathyResynchronization therapyImproved survivalMR reduction
2014
Chapter 6 Pathophysiology of Cardiomyopathies
Saini H, Tabtabai S, Stone J, Ellinor P. Chapter 6 Pathophysiology of Cardiomyopathies. 2014, 101-119. DOI: 10.1016/b978-0-12-405206-2.00006-5.Peer-Reviewed Original ResearchHeterogeneous group of disordersMolecular pathwaysCongestive heart failureLife-threatening arrhythmiasGroup of disordersIschemic heart diseaseMyocardial dysfunctionHeart failureTherapeutic modalitiesClinical symptomsCardiomyopathyMolecular basisGenetic mutationsSudden deathExtrinsic insultsHeart diseaseHeterogeneous groupCardiovascular conditionsDisease mechanismsFamily studiesDisease
2009
The Impact of a Multidisciplinary Approach in the Management of Patients with Acute Decompensated Heart Failure
Tabtabai S, Danielian A, Bernstein B, Arora S, Soucier R. The Impact of a Multidisciplinary Approach in the Management of Patients with Acute Decompensated Heart Failure. Journal Of Cardiac Failure 2009, 15: s118. DOI: 10.1016/j.cardfail.2009.06.051.Peer-Reviewed Original Research