2022
Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing
Kulkarni S, Flescher A, Ahmad M, Bayliss G, Bearl D, Biondi L, Davis E, George R, Gordon E, Lyons T, Wightman A, Ladin K. Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing. Journal Of Medical Ethics 2022, 49: 389-392. PMID: 34983855, PMCID: PMC10314075, DOI: 10.1136/medethics-2021-107574.Peer-Reviewed Original ResearchConceptsTransplant communityDonor transplantsTransplant hospitalsSARS-CoV-2 infectionHealth systemEnd-stage liverSARS-CoV-2Exposure riskDonor transplantationTransplant proceduresUnited NetworkKidney diseaseDialysis centersElective proceduresPatient preparednessTransplantEarly detectionCOVID-19 pandemicRiskHospitalRecipientsTier 3BAcceptable riskCareImportant option
2010
Use of model for end‐stage liver disease exception points for early liver transplantation and successful reversal of hepatic myelopathy with a review of the literature
Caldwell C, Werdiger N, Jakab S, Schilsky M, Arvelakis A, Kulkarni S, Emre S. Use of model for end‐stage liver disease exception points for early liver transplantation and successful reversal of hepatic myelopathy with a review of the literature. Liver Transplantation 2010, 16: 818-826. PMID: 20583082, DOI: 10.1002/lt.22077.Peer-Reviewed Original ResearchConceptsEarly liver transplantationHepatic myelopathyLiver transplantationSpastic paraparesisEnd-Stage Liver Disease (MELD) exception pointsEnd-Stage Liver Disease exceptionCases of LTException pointsCorticospinal tract functionFurther hepatic decompensationSetting of cirrhosisSignificant neurological improvementProgressive spastic paraparesisMELD exception pointsHepatic decompensationMELD scoreNeurological improvementFull ambulationNeurological benefitsPortosystemic shuntingHM patientsClinical stageUnited NetworkWheelchair dependencyEarly transplantation
2003
The sickest first? Disparities with model for end‐stage liver disease‐based organ allocation: One region's experience
Schaffer RL, Kulkarni S, Harper A, Millis JM, Cronin DC. The sickest first? Disparities with model for end‐stage liver disease‐based organ allocation: One region's experience. Liver Transplantation 2003, 9: 1211-1215. PMID: 14586883, DOI: 10.1053/jlts.2003.50192.Peer-Reviewed Original ResearchConceptsCadaver liversMELD scoreHepatocellular carcinomaOrgan allocationRegion patientsEnd-stage liver diseaseEquitable organ distributionMean MELD scoreMedian MELD scoreHigh MELD scoreLiver transplant programNumber of transplantationsOrgan Sharing regionsLiver recipientsPretransplantation mortalityMELD exceptionsLiver diseaseSingle centerUnited NetworkTransplant programsWaiting listTransplantationEvidence-based systemOrgan procurementTransplantation Network