2004
Pregnancy outcome of in vitro fertilization/intracytoplasmic sperm injection with profound teratospermia
McKenzie L, Kovanci E, Amato P, Cisneros P, Lamb D, Carson S. Pregnancy outcome of in vitro fertilization/intracytoplasmic sperm injection with profound teratospermia. Fertility And Sterility 2004, 82: 847-849. PMID: 15482758, DOI: 10.1016/j.fertnstert.2004.03.054.Peer-Reviewed Original ResearchConceptsIntracytoplasmic sperm injectionIVF/intracytoplasmic sperm injectionPregnancy outcomesSperm injectionFertilization/intracytoplasmic sperm injectionIVF/ICSI cyclesTertiary care centerAppropriate developmental milestonesBirth defectsStrict criteriaTime of deliveryKruger's strict criteriaYears of ageAcceptable pregnancy ratesOvarian stimulationICSI cyclesIncreased riskCare centerPregnancy rateRetrospective analysisMAIN OUTCOMETransvaginal aspirationEmbryo transferInfant statusSmall series
2002
Pregnancies following use of metformin for ovulation induction in patients with polycystic ovary syndrome
Heard M, Pierce A, Carson S, Buster J. Pregnancies following use of metformin for ovulation induction in patients with polycystic ovary syndrome. Fertility And Sterility 2002, 77: 669-673. PMID: 11937113, DOI: 10.1016/s0015-0282(01)03266-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnovulationClomipheneFemaleFertility Agents, FemaleHumansInfertility, FemaleMetforminOvulation InductionPolycystic Ovary SyndromePregnancyConceptsPolycystic ovary syndromeOvary syndromeSpontaneous abortionDiagnosis of PCOSAnovulatory infertility patientsUse of metforminResumption of mensesGastrointestinal-related side effectsEvidence of ovulationDosage of metforminAnovulatory patientsMetformin therapyPCOS resultsClomiphene citrateOvulation inductionPregnancy outcomesSpontaneous mensesInfertility patientsCase seriesMedian timeOvulatory responseMAIN OUTCOMESide effectsPatientsMetformin
2000
Dehydroepiandrosterone supplementation augments ovarian stimulation in poor responders: a case series
Casson P, Lindsay M, Pisarska M, Carson S, Buster J. Dehydroepiandrosterone supplementation augments ovarian stimulation in poor responders: a case series. Human Reproduction 2000, 15: 2129-2132. PMID: 11006185, DOI: 10.1093/humrep/15.10.2129.Peer-Reviewed Original ResearchConceptsHuman chorionic gonadotrophinOvarian stimulationDHEA treatmentPoor respondersPoor responseInsulin-like growth factor-1 effectsGrowth hormonePg/Healthy non-smoking womenDay 3 FSHOvarian stimulation responseOvarian stimulation cyclesNon-smoking womenPeak oestradiol concentrationsGonadotrophin doseDehydroepiandrosterone administrationGonadotrophin administrationOvarian responseCase seriesTwin pregnanciesMIU/Intrauterine inseminationOestradiol concentrationsFollicular maturityChorionic gonadotrophin
1999
Fertilization after standard in vitro fertilization versus intracytoplasmic sperm injection in subfertile males using sibling oocytes
Pisarska M, Casson P, Cisneros P, Lamb D, Lipshultz L, Buster J, Carson S. Fertilization after standard in vitro fertilization versus intracytoplasmic sperm injection in subfertile males using sibling oocytes. Fertility And Sterility 1999, 71: 627-632. PMID: 10202870, DOI: 10.1016/s0015-0282(98)00538-x.Peer-Reviewed Original ResearchConceptsSevere teratozoospermiaEmbryo qualityConventional IVFGroup AMale populationMean percentIntracytoplasmic sperm injectionProspective experimental studyFertilization rateIVF cyclesICSI cyclesOvulation inductionGroup BICSI resultsMore abnormalitiesMAIN OUTCOMESperm injectionIVFICSIIVF clinicsSubfertile malesHigher fertilization rateRandom allocationTeratozoospermiaSignificant differencesEfficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility
Guzick D, Carson S, Coutifaris C, Overstreet J, Factor-Litvak P, Steinkampf M, Hill J, Mastroianni L, Buster J, Nakajima S, Vogel D, Canfield R. Efficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility. New England Journal Of Medicine 1999, 340: 177-183. PMID: 9895397, DOI: 10.1056/nejm199901213400302.Peer-Reviewed Original ResearchConceptsIntrauterine insemination groupIntrauterine inseminationInduction of superovulationIntracervical inseminationCox proportional hazards analysisProportional hazards analysisTreatment of infertilityInfertility factorsClinical trialsInfertile couplesEfficacy of superovulationPregnancySuperovulationTreatmentInfertilityHigh rateMotile spermInseminationGroupInductionGonadotropinTrialsWomen
1996
Ovarian hyperstimulation augments adrenal dehydroepiandrosterone sulfate secretion**Supported in part by the American College of Obstetricians and Gynecologists-Ortho Academic Training Fellowship, of which Dr. Casson is the 1990-1991 recipient ††Presented in part at the Annual Meetings of the Canadian Fertility and Andrology Society, Quebec, Quebec, Canada, September 11 to 14, 1991; and Kananaskis, alberta, Canada, November 25 to 28, 1992
Casson P, Kristiansen S, Umstot E, Carson S, Buster J. Ovarian hyperstimulation augments adrenal dehydroepiandrosterone sulfate secretion**Supported in part by the American College of Obstetricians and Gynecologists-Ortho Academic Training Fellowship, of which Dr. Casson is the 1990-1991 recipient ††Presented in part at the Annual Meetings of the Canadian Fertility and Andrology Society, Quebec, Quebec, Canada, September 11 to 14, 1991; and Kananaskis, alberta, Canada, November 25 to 28, 1992. Fertility And Sterility 1996, 65: 950-953. PMID: 8612855, DOI: 10.1016/s0015-0282(16)58267-3.Peer-Reviewed Original ResearchConceptsOvarian hyperstimulationHyperstimulation cyclesSerum DHEAStandard ACTH testAdrenal androgen secretionSerum DHEAS levelsOvarian hyperstimulation cyclesProspective clinical studyMain outcome measuresPeak of stimulationDHEAS secretionOvulatory infertilityACTH testInfertile womenF secretionAndrogen secretionCanadian FertilityAndrology SocietyDHEAS levelsInfertility clinicNormal womenE2 levelsIntrapatient variabilityClinical studiesOutcome measures
1991
Superovulation fails to increase human blastocyst yield after uterine lavage
Carson S, Smith A, Scoggan J, Buster J. Superovulation fails to increase human blastocyst yield after uterine lavage. Prenatal Diagnosis 1991, 11: 513-522. PMID: 1766927, DOI: 10.1002/pd.1970110806.Peer-Reviewed Original ResearchConceptsUterine lavageFertile womenHuman chorionic gonadotropin administrationBlastocyst recoveryChorionic gonadotropin administrationBlastocyst yieldGonadotropin administrationOvulation inductionTotal fluid volumeLavage techniqueLavagePreimplantation genetic diagnosisFluid volumeInsemination timingWomenGenetic diagnosisDiagnosisDonor inseminationSuperovulationPreimplantation diagnosisEmbryo collectionDaysInseminationRegimensComplications