2023
Human Uterine Lavage: First Live Births from In Vivo Conceived Genetically Screened Blastocysts
Najmabadi S, Rivas J, Angle M, Nadal A, Bastu E, Munné S, Carson S, Buster J, Nakajima S. Human Uterine Lavage: First Live Births from In Vivo Conceived Genetically Screened Blastocysts. Advances In Therapy 2023, 40: 2534-2541. PMID: 36988819, DOI: 10.1007/s12325-023-02486-1.Peer-Reviewed Original ResearchConceptsFirst live birthEmbryo transfer proceduresLive birthsUterine lavageIntrauterine inseminationEuploid blastocystsOvarian stimulation cyclesObservational case seriesBlastocyst implantation ratePreimplantation genetic testingSets of twinsInfertile womenCase seriesLavage catheterImplantation rateTransfer procedureFertility centerOocyte aspirationStimulation cyclesInfertile couplesLavage procedureSurgical proceduresEmbryo implantationMethodsIn vivoOocyte donors
2009
Stress, workload, sexual well‐being and quality of life among physician residents in training
Sangi‐Haghpeykar H, Ambani D, Carson S. Stress, workload, sexual well‐being and quality of life among physician residents in training. International Journal Of Clinical Practice 2009, 63: 462-467. PMID: 19222631, DOI: 10.1111/j.1742-1241.2008.01845.x.Peer-Reviewed Original ResearchConceptsQuality of lifeSexual healthSexual dysfunctionMedical residentsNormal sexual functioningYears of residencySexual functioningPhysician residentsFemale residentsMale residentsSexual lifeMajority of residentsSexual activityHigh levelsFemale medical residentsDysfunctionMost domainsImpact of stressResidency programsHealthLevel of stressSignificant improvementResidencyQuestionnaireResidents
2005
Preimplantation Genetic Diagnosis (PGD) for Heritable Neoplasia
Simpson J, Carson S, Cisneros P. Preimplantation Genetic Diagnosis (PGD) for Heritable Neoplasia. JNCI Monographs 2005, 2005: 87-90. PMID: 15784832, DOI: 10.1093/jncimonographs/lgi027.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiopsyBlastocystBlastomeresCord Blood Stem Cell TransplantationEmbryo TransferFemaleGenetic CounselingGenetic Diseases, InbornGenetic Predisposition to DiseaseGenotypeHLA AntigensHumansInfant, NewbornMaleNeoplasmsPregnancyPregnancy OutcomePreimplantation DiagnosisTruth DisclosureWillsConceptsAdenomatous polyposis coliPreimplantation genetic diagnosisMolecular basisGenetic diagnosisMendelian disordersMendelian formsPolyposis coliEmbryosVon Hippel-Lindau syndromeMore cellsLi-Fraumeni syndromeGametesGenesPolar body biopsyDNADays postconceptionColiTransfer of embryosBlastocystsTrophectoderm biopsyStem cell implantationBRCA1Specific HLA genotypesGenotypesCells
2004
Pregnancy outcome of in vitro fertilization/intracytoplasmic sperm injection with profound teratospermia
McKenzie L, Kovanci E, Amato P, Cisneros P, Lamb D, Carson S. Pregnancy outcome of in vitro fertilization/intracytoplasmic sperm injection with profound teratospermia. Fertility And Sterility 2004, 82: 847-849. PMID: 15482758, DOI: 10.1016/j.fertnstert.2004.03.054.Peer-Reviewed Original ResearchConceptsIntracytoplasmic sperm injectionIVF/intracytoplasmic sperm injectionPregnancy outcomesSperm injectionFertilization/intracytoplasmic sperm injectionIVF/ICSI cyclesTertiary care centerAppropriate developmental milestonesBirth defectsStrict criteriaTime of deliveryKruger's strict criteriaYears of ageAcceptable pregnancy ratesOvarian stimulationICSI cyclesIncreased riskCare centerPregnancy rateRetrospective analysisMAIN OUTCOMETransvaginal aspirationEmbryo transferInfant statusSmall seriesPaternal gonadal mosaicism detected in a couple with recurrent abortions undergoing PGD: FISH analysis of sperm nuclei proves valuable
Somprasit C, Aguinaga M, Cisneros P, Torsky S, Carson S, Buster J, Amato P, McAdoo S, Simpson J, Bischoff F. Paternal gonadal mosaicism detected in a couple with recurrent abortions undergoing PGD: FISH analysis of sperm nuclei proves valuable. Reproductive BioMedicine Online 2004, 9: 225-230. PMID: 15333256, DOI: 10.1016/s1472-6483(10)62134-7.Peer-Reviewed Original ResearchConceptsPaternal gonadal mosaicismSpontaneous abortionPreimplantation genetic diagnosisIVF-PGD cyclesRecurrent spontaneous abortionGonadal mosaicismIVF cyclesPaternal germ cellsPeripheral bloodRecurrent abortionCase reportPGD cyclesNormal karyotypeFemale partnersAbortionGenetic diagnosisIVFCytogenetic studiesDown syndrome critical regionGerm cellsUnexpected findingSitu hybridizationNormal embryosMosaicism
2003
Preimplantation genetic diagnosis for a known cryptic translocation: Follow‐up clinical report and implication of segregation products
McKenzie L, Cisneros P, Torsky S, Bacino C, Buster J, Carson S, Simpson J, Bischoff F. Preimplantation genetic diagnosis for a known cryptic translocation: Follow‐up clinical report and implication of segregation products. American Journal Of Medical Genetics Part A 2003, 121A: 56-59. PMID: 12900903, DOI: 10.1002/ajmg.a.20159.Peer-Reviewed Original ResearchConceptsPreimplantation genetic diagnosisCryptic translocationMaternal age-related aneuploidyAge-related aneuploidyGenetic diagnosisChromosome 17 centromere probeSevere mental retardationChorionic villus samplingUnbalanced productsPregnancy terminationClinical reportsEmpiric riskVillus samplingTransferable embryosMental retardationFrequent modeNormal offspringDiagnosisChildrenReportTranslocationUnbalanced segregants
2001
Sperm Morphology, Motility, and Concentration in Fertile and Infertile Men
Guzick D, Overstreet J, Factor-Litvak P, Brazil C, Nakajima S, Coutifaris C, Carson S, Cisneros P, Steinkampf M, Hill J, Xu D, Vogel D. Sperm Morphology, Motility, and Concentration in Fertile and Infertile Men. New England Journal Of Medicine 2001, 345: 1388-1393. PMID: 11794171, DOI: 10.1056/nejmoa003005.Peer-Reviewed Original Research
1999
Fertilization after standard in vitro fertilization versus intracytoplasmic sperm injection in subfertile males using sibling oocytes
Pisarska M, Casson P, Cisneros P, Lamb D, Lipshultz L, Buster J, Carson S. Fertilization after standard in vitro fertilization versus intracytoplasmic sperm injection in subfertile males using sibling oocytes. Fertility And Sterility 1999, 71: 627-632. PMID: 10202870, DOI: 10.1016/s0015-0282(98)00538-x.Peer-Reviewed Original ResearchConceptsSevere teratozoospermiaEmbryo qualityConventional IVFGroup AMale populationMean percentIntracytoplasmic sperm injectionProspective experimental studyFertilization rateIVF cyclesICSI cyclesOvulation inductionGroup BICSI resultsMore abnormalitiesMAIN OUTCOMESperm injectionIVFICSIIVF clinicsSubfertile malesHigher fertilization rateRandom allocationTeratozoospermiaSignificant differencesThe reproductive option of sex selection
Simpson J, Carson S. The reproductive option of sex selection. Human Reproduction 1999, 14: 870-872. PMID: 10221210, DOI: 10.1093/humrep/14.4.870.Peer-Reviewed Original ResearchEfficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility
Guzick D, Carson S, Coutifaris C, Overstreet J, Factor-Litvak P, Steinkampf M, Hill J, Mastroianni L, Buster J, Nakajima S, Vogel D, Canfield R. Efficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility. New England Journal Of Medicine 1999, 340: 177-183. PMID: 9895397, DOI: 10.1056/nejm199901213400302.Peer-Reviewed Original ResearchConceptsIntrauterine insemination groupIntrauterine inseminationInduction of superovulationIntracervical inseminationCox proportional hazards analysisProportional hazards analysisTreatment of infertilityInfertility factorsClinical trialsInfertile couplesEfficacy of superovulationPregnancySuperovulationTreatmentInfertilityHigh rateMotile spermInseminationGroupInductionGonadotropinTrialsWomen
1997
Effect of sexual abstinence on the proportion of X-bearing sperm as assessed by multicolor fluorescent in situ hybridization
Hilsenrath R, Swarup M, Bischoff F, Buster J, Carson S. Effect of sexual abstinence on the proportion of X-bearing sperm as assessed by multicolor fluorescent in situ hybridization. Fertility And Sterility 1997, 68: 510-513. PMID: 9314924, DOI: 10.1016/s0015-0282(97)00247-1.Peer-Reviewed Original Research
1996
Prospective study showing that antisperm antibodies are not associated with pregnancy losses**Supported by a contract with the National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Simpson J, Carson S, Mills J, Conley M, Aarons J, Holmes L, Jovanovic-Peterson L, Knopp R, Metzger B. Prospective study showing that antisperm antibodies are not associated with pregnancy losses**Supported by a contract with the National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland. Fertility And Sterility 1996, 66: 36-42. PMID: 8752608, DOI: 10.1016/s0015-0282(16)58384-8.Peer-Reviewed Original ResearchConceptsIgM antisperm antibodiesAntisperm antibodiesPregnancy lossIgA antisperm antibodiesNondiabetic womenPregnancy outcomesPositive findingsFirst trimester pregnancy lossTrimester pregnancy lossFirst-trimester serumIndirect immunobead testNational InstituteOnly positive findingDay of conceptionMaternal serumClinical statusProspective studyImmunobead testLiveborn infantsProspective dataChild healthPositive testIgM bindingRegional bindingLocation of antibody
1995
Flow cytometry provides rapid and highly accurate detection of antisperm antibodies*†*Supported by a grant from the University of Tennessee Medical Group, Inc., Memphis, Tennessee.†Presented at the Conjoint Annual Meeting of The American Fertility Society and the Canadian Fertility and Andrology Society, Montreal, Quebec, October 11 to 14, 1993.
Ke R, Dockter M, Majumdar G, Buster J, Carson S. Flow cytometry provides rapid and highly accurate detection of antisperm antibodies*†*Supported by a grant from the University of Tennessee Medical Group, Inc., Memphis, Tennessee.†Presented at the Conjoint Annual Meeting of The American Fertility Society and the Canadian Fertility and Andrology Society, Montreal, Quebec, October 11 to 14, 1993. Fertility And Sterility 1995, 63: 902-906. PMID: 7890080, DOI: 10.1016/s0015-0282(16)57501-3.Peer-Reviewed Original ResearchConceptsIgM antisperm antibodiesAntisperm antibodiesFlow cytometryConjoint Annual MeetingSerum antisperm antibodiesAmerican Fertility SocietyDetection of IgGAntisperm antibody detectionStudy patientsCanadian FertilityAndrology SocietyFertility SocietyCytometry laboratoriesFertile menAntibody detectionMedical groupIgASerumCytometryAntibodiesTest seraNegative seraCurrent standardMenFluorescence intensity values
1994
Intrauterine insemination in fertile women delivers larger numbers of sperm to the peritoneal fluid than intracervical insemination**Presented at the 40th Annual Meeting of the Society for Gynecologic Investigation, Toronto, Ontario, Canada, March 31 to April 4, 1993.
Ripps B, Minhas B, Carson S, Buster J. Intrauterine insemination in fertile women delivers larger numbers of sperm to the peritoneal fluid than intracervical insemination**Presented at the 40th Annual Meeting of the Society for Gynecologic Investigation, Toronto, Ontario, Canada, March 31 to April 4, 1993. Fertility And Sterility 1994, 61: 398-400. PMID: 8299805, DOI: 10.1016/s0015-0282(16)56540-6.Peer-Reviewed Original Research
1991
CASE REPORT
Carson S, Gentry W, Smith A, Buster J. CASE REPORT. Human Reproduction 1991, 6: 992-994. PMID: 1761672, DOI: 10.1093/oxfordjournals.humrep.a137475.Peer-Reviewed Original Research
1989
Failure to demonstrate significant antisperm antibodies in peritoneal fluid of patients with endometriosis
Gentry W, Buster J, Schriock E, Carson S. Failure to demonstrate significant antisperm antibodies in peritoneal fluid of patients with endometriosis. Fertility And Sterility 1989, 52: 949-952. PMID: 2591573, DOI: 10.1016/s0015-0282(16)53157-4.Peer-Reviewed Original ResearchConceptsAntisperm antibodiesPeritoneal fluidSperm phagocytosisSerum autoimmune antibodiesInfertile controlsEndometriosis patientsImmunologic disordersAutoimmune antibodiesMild casesEndometriosisPatientsPeritoneal macrophagesMonthly fecundityAntibodiesPhagocytosisPossible increaseInfertilityDiseaseMacrophagesImmunobeads
1988
Sex selection: the ultimate in family planning
Carson S. Sex selection: the ultimate in family planning. Fertility And Sterility 1988, 50: 16-19. PMID: 3164280, DOI: 10.1016/s0015-0282(16)60000-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAntibody binding patterns in infertile males and females as detected by immunobead test, gel-agglutination test, and sperm immobilization test
Carson S, Reiher J, Scommegna A, Prins G. Antibody binding patterns in infertile males and females as detected by immunobead test, gel-agglutination test, and sperm immobilization test. Fertility And Sterility 1988, 49: 487-492. PMID: 3277868, DOI: 10.1016/s0015-0282(16)59778-7.Peer-Reviewed Original Research
1983
Heritable aspects of uterine anomalies. I. Three familial aggregates with Müllerian fusion anomalies**Supported in part by NIH grants HD 11021 and HD 02841, and grants from the March of Dimes.
Verp M, Simpson J, Elias S, Carson S, Sarto G, Feingold M. Heritable aspects of uterine anomalies. I. Three familial aggregates with Müllerian fusion anomalies**Supported in part by NIH grants HD 11021 and HD 02841, and grants from the March of Dimes. Fertility And Sterility 1983, 40: 80-85. PMID: 6862042, DOI: 10.1016/s0015-0282(16)47181-5.Peer-Reviewed Original Research