2023
Human Uterine Lavage: First Live Births from In Vivo Conceived Genetically Screened Blastocysts
Najmabadi S, Rivas J, Angle M, Nadal A, Bastu E, Munné S, Carson S, Buster J, Nakajima S. Human Uterine Lavage: First Live Births from In Vivo Conceived Genetically Screened Blastocysts. Advances In Therapy 2023, 40: 2534-2541. PMID: 36988819, DOI: 10.1007/s12325-023-02486-1.Peer-Reviewed Original ResearchConceptsFirst live birthEmbryo transfer proceduresLive birthsUterine lavageIntrauterine inseminationEuploid blastocystsOvarian stimulation cyclesObservational case seriesBlastocyst implantation ratePreimplantation genetic testingSets of twinsInfertile womenCase seriesLavage catheterImplantation rateTransfer procedureFertility centerOocyte aspirationStimulation cyclesInfertile couplesLavage procedureSurgical proceduresEmbryo implantationMethodsIn vivoOocyte donors
2010
Predictors of Pregnancy in Women With Polycystic Ovary Syndrome
Rausch M, Legro R, Barnhart H, Schlaff W, Carr B, Diamond M, Carson S, Steinkampf M, McGovern P, Cataldo N, Gosman G, Nestler J, Giudice L, Leppert P, Myers E, Coutifaris C. Predictors of Pregnancy in Women With Polycystic Ovary Syndrome. Obstetrical & Gynecological Survey 2010, 65: 30-32. DOI: 10.1097/01.ogx.0000367515.48912.b1.Peer-Reviewed Original ResearchPolycystic ovary syndromeClomiphene citrateLive birthsOvary syndromeTreatment successCurrent first-line treatmentSelective estrogen receptor modulatorsBaseline patient characteristicsFirst-line treatmentFree androgen indexPredictors of pregnancyPrior pregnancy lossPrimary study outcomeBody mass indexInsulin sensitizer metforminEstrogen receptor modulatorsRelevant prognostic modelHirsutism scoreAndrogen indexGlucose intoleranceOvulation inductionPatient characteristicsPregnancy outcomesSmoking historyInfertile women
2007
Clomiphene, Metformin, or Both for Infertility in the Polycystic Ovary Syndrome
Legro R, Barnhart H, Schlaff W, Carr B, Diamond M, Carson S, Steinkampf M, Coutifaris C, McGovern P, Cataldo N, Gosman G, Nestler J, Giudice L, Leppert P, Myers E. Clomiphene, Metformin, or Both for Infertility in the Polycystic Ovary Syndrome. Obstetrical & Gynecological Survey 2007, 62: 386-388. DOI: 10.1097/01.ogx.0000265909.61668.01.Peer-Reviewed Original ResearchPolycystic ovary syndromeExtended-release metforminMetformin groupLive birthsTreatment groupsClomiphene citrateOvary syndromeInfertile womenPregnancy lossSex hormone-binding globulin levelsAbstract Polycystic ovary syndromeHormone-binding globulin levelsFirst trimester pregnancy lossClomiphene-treated patientsDose of clomipheneMetformin-treated womenPlacebo-controlled trialSerious adverse eventsFirst-line treatmentFree androgen indexLive birth rateGastrointestinal side effectsBody mass indexEarly pregnancy lossSingle drug group
2004
Absence of secretory endometrium after false-positive home urine luteinizing hormone testing
McGovern P, Myers E, Silva S, Coutifaris C, Carson S, Legro R, Schlaff W, Carr B, Steinkampf M, Giudice L, Leppert P, Diamond M, Network N. Absence of secretory endometrium after false-positive home urine luteinizing hormone testing. Fertility And Sterility 2004, 82: 1273-1277. PMID: 15533341, DOI: 10.1016/j.fertnstert.2004.03.070.Peer-Reviewed Original ResearchConceptsProportion of casesEndometrial biopsyProliferative endometriumLH testingHealth/National InstituteReproductive Medicine NetworkEvaluation of infertilityRegular menstrual cyclesAdditional confirmatory testingMulticenter clinical trialLate luteal phaseNational InstituteFalse-positive testsInfertile womenHormone testingSecretory endometriumMenstrual cycleClinical trialsLH testLuteal phaseInfertile couplesMAIN OUTCOMEChild healthFertile volunteersClinical practiceHistological dating of timed endometrial biopsy tissue is not related to fertility status
Coutifaris C, Myers E, Guzick D, Diamond M, Carson S, Legro R, McGovern P, Schlaff W, Carr B, Steinkampf M, Silva S, Vogel D, Leppert P, Network N. Histological dating of timed endometrial biopsy tissue is not related to fertility status. Fertility And Sterility 2004, 82: 1264-1272. PMID: 15533340, DOI: 10.1016/j.fertnstert.2004.03.069.Peer-Reviewed Original ResearchConceptsLate luteal phaseHistological datingInfertile couplesPhase biopsiesLuteal phaseCycle dayDaily urinary LH testingReproductive Medicine NetworkUrinary LH testingProspective multicenter studyRegular menstrual cyclesRecurrent pregnancy lossHistory of infertilityEndometrial biopsy tissueLogistic regression modelsInfertile womenInfertility practiceLH surgeMulticenter studyRegular intercourseBiopsy resultsPregnancy lossMenstrual cycleInclusion criteriaLive births
1996
Ovarian hyperstimulation augments adrenal dehydroepiandrosterone sulfate secretion**Supported in part by the American College of Obstetricians and Gynecologists-Ortho Academic Training Fellowship, of which Dr. Casson is the 1990-1991 recipient ††Presented in part at the Annual Meetings of the Canadian Fertility and Andrology Society, Quebec, Quebec, Canada, September 11 to 14, 1991; and Kananaskis, alberta, Canada, November 25 to 28, 1992
Casson P, Kristiansen S, Umstot E, Carson S, Buster J. Ovarian hyperstimulation augments adrenal dehydroepiandrosterone sulfate secretion**Supported in part by the American College of Obstetricians and Gynecologists-Ortho Academic Training Fellowship, of which Dr. Casson is the 1990-1991 recipient ††Presented in part at the Annual Meetings of the Canadian Fertility and Andrology Society, Quebec, Quebec, Canada, September 11 to 14, 1991; and Kananaskis, alberta, Canada, November 25 to 28, 1992. Fertility And Sterility 1996, 65: 950-953. PMID: 8612855, DOI: 10.1016/s0015-0282(16)58267-3.Peer-Reviewed Original ResearchConceptsOvarian hyperstimulationHyperstimulation cyclesSerum DHEAStandard ACTH testAdrenal androgen secretionSerum DHEAS levelsOvarian hyperstimulation cyclesProspective clinical studyMain outcome measuresPeak of stimulationDHEAS secretionOvulatory infertilityACTH testInfertile womenF secretionAndrogen secretionCanadian FertilityAndrology SocietyDHEAS levelsInfertility clinicNormal womenE2 levelsIntrapatient variabilityClinical studiesOutcome measures