Samuel Reinhardt, MD, FACC
Assistant Professor of Medicine (Cardiovascular Medicine)Cards
About
Research
Publications
2024
Anticoagulation Alone vs Anticoagulation Plus Aspirin or DAPT Following Left Atrial Appendage Occlusion
Reinhardt S, Gibson D, Hsu J, Kapadia S, Yeh R, Price M, Piccini J, Nair D, Christen T, Allocco D, Freeman J. Anticoagulation Alone vs Anticoagulation Plus Aspirin or DAPT Following Left Atrial Appendage Occlusion. Journal Of The American College Of Cardiology 2024, 84: 889-900. PMID: 39197978, DOI: 10.1016/j.jacc.2024.05.067.Peer-Reviewed Original ResearchConceptsLeft atrial appendage occlusionRate of adverse eventsAdverse eventsLAA closure deviceAppendage occlusionAntithrombotic strategiesP2Y<sub>12</sub> inhibitorsDays of follow-upMultivariable Cox proportional hazards regressionClosure deviceRisk of adverse eventsCox proportional hazards regressionWatchman FLX deviceDual antiplatelet therapyDevice-related thrombusProportional hazards regressionStroke/transient ischemic attackAntithrombotic regimensFLX deviceAntiplatelet therapyDOACsGroup patientsFollow-upMultivariate analysisHazards regressionImplementing Formal Mitral Heart Team Improves Multidisciplinary Evaluation Rate and Survival of Patients With Severe Primary Mitral Regurgitation
Waldron C, Mori M, Krane M, Reinhardt S, Ahmad Y, Kaple R, Forrest J, Geirsson A. Implementing Formal Mitral Heart Team Improves Multidisciplinary Evaluation Rate and Survival of Patients With Severe Primary Mitral Regurgitation. Journal Of The American Heart Association 2024, 13: e033324. PMID: 38390804, PMCID: PMC11179864, DOI: 10.1161/jaha.123.033324.Peer-Reviewed Original ResearchSevere primary mitral regurgitationPrimary mitral regurgitationHeart failure symptomsMitral regurgitationMultidisciplinary evaluationPatient survivalHeart teamFailure symptomsSociety of Thoracic Surgeons Predicted Risk of MortalityThoracic Surgeons Predicted Risk of MortalityImprove overall patient survivalCorrection of MRAssociated with lower oddsMultidisciplinary heart teamSurvival of patientsAssociated with higher oddsOverall patient survivalProportion of patientsRetrospective cohort studyCardiac surgery servicesHistory of MIOptimal treatment decisionsPropensity-score matchingRisk of mortalityStructural cardiologyFactors associated with reporting left ventricular ejection fraction with 3D echocardiography in real‐world practice
Faridi K, Zhu Z, Shah N, Crandall I, McNamara R, Flueckiger P, Bachand K, Lombo B, Hur D, Agarwal V, Reinhardt S, Velazquez E, Sugeng L. Factors associated with reporting left ventricular ejection fraction with 3D echocardiography in real‐world practice. Echocardiography 2024, 41: e15774. PMID: 38329886, DOI: 10.1111/echo.15774.Peer-Reviewed Original ResearchConceptsTransthoracic echocardiogramVentricular ejection fractionOutpatient transthoracic echocardiogramsReal-world practiceEjection fractionLeft ventricular ejection fractionAssess left ventricular ejection fractionInpatient transthoracic echocardiogramsMultivariate logistic regressionLVEFHospitalized patientsMedical CenterSonographersClinical settingLogistic regressionUltrasound machineChemotherapyContrast enhancement agentsPortable studiesNegative associationImplementing Formal Mitral Heart Team Improves Multidisciplinary Evaluation Rate and Survival of Patients with Severe Primary Mitral Regurgitation
Waldron C, Mori M, Krane M, Reinhardt SW, Ahmad Y, Kaple R, Forrest JK, Geirrson A. Implementing Formal Mitral Heart Team Improves Multidisciplinary Evaluation Rate and Survival of Patients with Severe Primary Mitral Regurgitation. J Am Heart Assoc. Accepted Jan 17 2024.Peer-Reviewed Original Research In PressAnticoagulation Alone vs Anticoagulation Plus Aspirin or DAPT Following Watchman FLX Left Atrial Appendage Occlusion
Reinhardt SW, Gibson, DN, Hsu JC, Kapadia SR, Yeh RW, Price MJ, Piccini JP, Nair DG, Christen T, Allocco DJ, Freeman JV. Anticoagulation Alone vs Anticoagulation Plus Aspirin or DAPT Following Watchman FLX Left Atrial Appendage Occlusion. Submitted to J Amer Coll Cardiology Jan 4 2024Peer-Reviewed Original Research In Press
2023
Variation in Reader-Reported Severity of Paradoxical Low-Flow Low-Gradient Aortic Stenosis
Shah N, Sugeng L, Zhang Z, Wang K, McNamara R, Agarwal V, Hur D, Lombo B, Bellumkonda L, Mankbadi M, Basem Dajani A, Forrest J, Krumholz H, Reinhardt S, Velazquez E, Faridi K. Variation in Reader-Reported Severity of Paradoxical Low-Flow Low-Gradient Aortic Stenosis. Journal Of The American Society Of Echocardiography 2023, 37: 466-467. PMID: 37995937, DOI: 10.1016/j.echo.2023.11.014.Peer-Reviewed Original ResearchMyocardial Injury on CMR in Patients With COVID-19 and Suspected Cardiac Involvement
Vidula MK, Rajewska-Tabor J, Cao JJ, Kang Y, Craft J, Mei W, Chandrasekaran PS, Clark DE, Poenar AM, Gorecka M, Malahfji M, Cowan E, Kwan JM, Reinhardt SW, Al-Tabatabaee S, Doeblin P, Villa ADM, Karagodin I, Alvi N, Christia P, Spetko N, Cassar MP, Park C, Nambiar L, Turgut A, Azad MR, Lambers M, Wong TC, Salerno M, Kim J, Elliott M, Raman B, Neubauer S, Tsao CW, LaRocca G, Patel AR, Chiribiri A, Kelle S, Baldassarre LA, Shah DJ, Hughes SG, Tong MS, Pyda M, Simonetti OP, Plein S, Han Y. Myocardial Injury on CMR in Patients With COVID-19 and Suspected Cardiac Involvement. JACC Cardiovasc Imaging. 2023 Jan 11. doi: 10.1016/j.jcmg.2022.10.021. Epub ahead of print. PMCID: PMC9833283.Peer-Reviewed Original Research
2022
Thirty-Day and 90-Day Episode of Care Spending Following Heart Failure Hospitalization Among Medicare Beneficiaries
Reinhardt SW, Clark KAA, Xin X, Parzynski CS, Riello R, Sarocco P, Ahmad T, Desai NR. Thirty-Day and 90-Day Episode of Care Spending Following Heart Failure Hospitalization Among Medicare Beneficiaries. Circulation Cardiovascular Quality And Outcomes 2022, 15: e008069. PMID: 35861780, DOI: 10.1161/circoutcomes.121.008069.Peer-Reviewed Original ResearchConceptsHypertensive heart diseaseIndex hospitalizationMedicare beneficiariesPost-acute care spendingService administrative claims dataMedicare Bundled PaymentsHeart failure admissionsHeart failure hospitalizationPrimary discharge diagnosisChronic kidney diseaseAdministrative claims dataCare spendingPostacute care spendingSkilled nursing facilitiesCare Improvement ProgramDrivers of costDiastolic HFHF careHF hospitalizationSystolic HFFailure hospitalizationDischarge diagnosisKidney diseaseObservation staysPostacute careTrends In US Heart Failure Hospitalizations: Increased Volume And Patient Diversity With Decreased Total Costs, 2008-2018
Reinhardt S, Clark K, Chouairi F, Miller E, Kay B, Fuery M, Guha A, Ahmad T, Desai N. Trends In US Heart Failure Hospitalizations: Increased Volume And Patient Diversity With Decreased Total Costs, 2008-2018. Journal Of Cardiac Failure 2022, 28: s109-s110. DOI: 10.1016/j.cardfail.2022.03.280.Peer-Reviewed Original ResearchOverall heart failureHeart failureInpatient mortalityDiagnosis codesHospital costsChronic obstructive pulmonary diseaseIntroduction Heart failureHeart failure hospitalizationPeripheral arterial diseaseObstructive pulmonary diseaseCoronary artery diseaseNational Inpatient SampleLength of stayUS healthcare costsComorbid diabetesHF hospitalizationHospitalization volumeFailure hospitalizationHF cohortArtery diseaseEjection fractionMedian agePulmonary diseaseArterial diseaseHispanic patientsContemporary US Trends In Heart Transplantation And LVAD Index Hospitalizations: Volumes Increase, Utilization And Cost Vary Over Time, 2015-2018
Clark K, Reinhardt S, Chouairi F, Miller E, Kay B, Fuery M, Guha A, Ahmad T, Desai N. Contemporary US Trends In Heart Transplantation And LVAD Index Hospitalizations: Volumes Increase, Utilization And Cost Vary Over Time, 2015-2018. Journal Of Cardiac Failure 2022, 28: s65. DOI: 10.1016/j.cardfail.2022.03.165.Peer-Reviewed Original ResearchLength of stayHeart transplantationHospital mortalityIndex hospitalizationLVAD implantationLonger median LOSMedian LOSLonger LOSPost-discharge utilizationNational Inpatient SampleHospitalization volumeInpatient mortalityHispanic patientsAsian patientsInpatient SampleHospitalizationMortalityStudy periodUS trendsPatientsTransplantationAdmissionLVADImplantationHigh percentage
Academic Achievements & Community Involvement
Clinical Care
Overview
Sam Reinhardt, MD, is a cardiologist who specializes in advanced cardiac imaging, including structural echocardiography, cardiac MRI, and cardiac CT. He is also a member of the Structural Cardiology team, which focuses on treating patients with valvular disease (problems with the heart valves) through both less-invasive methods and open heart surgery.
Dr. Reinhardt particularly enjoys guiding minimally invasive (structural) cardiac interventions as the procedural echocardiographer. The interventional cardiologists on the team rely on him to show the cardiac valve of interest during the procedure and guide them as they place the device to fix the problem. He enjoys how these procedures can quickly give patients significant relief from their symptoms.
When interacting with patients, Dr. Reinhardt focuses on building a connection early. “I make sure the patient understands I see them as a whole person, not just someone with a heart condition,” he says. “I want to know where they are from, what their lives are like, what they enjoy doing, and how their disease is impacting their day-to-day life. Building relationships is one of the most rewarding parts of being a cardiologist.”
An assistant professor of cardiology at Yale School of Medicine, Dr. Reinhardt has been involved in researching different factors that affect patient outcomes in heart failure, including in left ventricular assist device (LVAD) and heart transplant patients. More recently, he has focused on valvular heart disease and different metrics to use to determine the severity of valvular pathology. He is involved in multiple ongoing clinical trials at Yale School of Medicine involving new therapies to treat valvular heart disease through minimally invasive approaches.
Clinical Specialties
Fact Sheets
Cardiomyopathies
Learn More on Yale Medicine
Board Certifications
Cardiovascular Disease
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2021
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2017
Yale Medicine News
News
News
- August 27, 2024Source: TCTMD
Dropping Aspirin From Post-LAAO Regimens Seems Like a Good Idea
- August 17, 2022
AHA Scientific Sessions 2022: Latest updates from Yale Cardiovascular Medicine
- July 27, 2022
New Appointments & Promotions Within Department of Internal Medicine
- July 01, 2022
Yale Cardiovascular Medicine Appoints Fellows to Faculty Positions