MAPT (Tau) expression is a biomarker for an increased rate of survival for low-grade glioma
Zaman S, Chobrutskiy BI, Sikaria D, Blanck G. MAPT (Tau) expression is a biomarker for an increased rate of survival for low-grade glioma. Oncology Reports 2018, 41: 1359-1366. PMID: 30535461, DOI: 10.3892/or.2018.6896.Peer-Reviewed Original ResearchMAPT expressionSurvival rateΑ-synuclein gene expressionDisease-free survivalCentral nervous systemLow-grade gliomasAssociation of MAPTRate of survivalCancer Genome AtlasBreast cancerNeurodegenerative roleTau expressionBrain cancerNervous systemNeurological disordersTau proteinMAPT geneHigh expressionCancerGenome AtlasPrecursor proteinExpression levelsSuch associationsSurvivalTauRecovery of T-cell receptor V(D)J recombination reads from lower grade glioma exome files correlates with reduced survival and advanced cancer grade
Chobrutskiy BI, Zaman S, Tong WL, Diviney A, Blanck G. Recovery of T-cell receptor V(D)J recombination reads from lower grade glioma exome files correlates with reduced survival and advanced cancer grade. Journal Of Neuro-Oncology 2018, 140: 697-704. PMID: 30382482, DOI: 10.1007/s11060-018-03001-1.Peer-Reviewed Original ResearchConceptsLow-grade gliomasT cell receptorCancer gradeImmune systemExome filesT-cell biomarkersDisease-free survivalT lymphocyte infiltrationPrimary tumor siteLGG survivalLymphocyte infiltrationCancer survivalPrimary tumorPancreatic cancerDisease progressionUseful biomarkerB cellsGrade gliomasSurvival rateTumor siteReduced survivalSurvivalSuch associationsBiomarkersReceptors