2015
Reelin Prevents Apical Neurite Retraction during Terminal Translocation and Dendrite Initiation
O'Dell RS, Cameron DA, Zipfel WR, Olson EC. Reelin Prevents Apical Neurite Retraction during Terminal Translocation and Dendrite Initiation. Journal Of Neuroscience 2015, 35: 10659-10674. PMID: 26224852, PMCID: PMC4518046, DOI: 10.1523/jneurosci.1629-15.2015.Peer-Reviewed Original ResearchConceptsApical dendritesCortical laminationGlycoprotein ReelinMigration arrestPrimary neuritesMarginal zoneNormal target areaWild-type neuronsSubset of neuronsReeler cortexReeler neuronsDendritic arborsDendritic outgrowthReelin functionMouse cortexReelin proteinNeuronal migrationNeuronsLeading processCortexReelinMin periodNeurite retractionNeuritesTerminal phase
2012
Layer 6 cortical neurons require Reelin-Dab1 signaling for cellular orientation, Golgi deployment, and directed neurite growth into the marginal zone
O’Dell R, Ustine CJ, Cameron DA, Lawless SM, Williams RM, Zipfel WR, Olson EC. Layer 6 cortical neurons require Reelin-Dab1 signaling for cellular orientation, Golgi deployment, and directed neurite growth into the marginal zone. Neural Development 2012, 7: 25. PMID: 22770513, PMCID: PMC3466444, DOI: 10.1186/1749-8104-7-25.Peer-Reviewed Original ResearchConceptsEarly cortical developmentMutant cortexCortical neuronsCortical developmentPial surfaceMarginal zoneApical neuritesL6 neuronsRecombinant ReelinNeocortical neuronsNeuronal somataReelin-Dab1Arbor lengthArbor sizeExplant modelVentricular zonePioneer neuronsMutant neuronsReelinNeuronsConclusionsThese findingsMore primary processesNeuronal orientationCortexNeurite growth