2022
Human biodistribution and radiation dosimetry of the demyelination tracer [18F]3F4AP
Brugarolas P, Wilks M, Noel J, Kaiser J, Vesper D, Ramos-Torres K, Guehl N, Macdonald-Soccorso M, Sun Y, Rice P, Yokell D, Lim R, Normandin M, El Fakhri G. Human biodistribution and radiation dosimetry of the demyelination tracer [18F]3F4AP. European Journal Of Nuclear Medicine And Molecular Imaging 2022, 50: 344-351. PMID: 36197499, PMCID: PMC9816249, DOI: 10.1007/s00259-022-05980-w.Peer-Reviewed Original ResearchConceptsRadiation dosimetryTime-activity curvesAdverse eventsEffective doseMultiple bed positionsComprehensive metabolic panelNonhuman primatesHealthy human volunteersNo adverse eventsDynamic PET scansVoltage-gated potassiumAnimal models of neurological diseasesNonhuman primate studiesModels of neurological diseasesHuman biodistributionAverage effective doseMetabolic panelDosimetryOLINDA softwareHealthy volunteersUrinary bladderPET scansDemyelinating lesionsBed positionAnimal models
2015
Simplifying size-specific radiation dose estimates in pediatric CT.
Khawaja R, Singh S, Vettiyil B, Lim R, Gee M, Westra S, Kalra M. Simplifying size-specific radiation dose estimates in pediatric CT. American Journal Of Roentgenology 2015, 204: 167-76. PMID: 25539253, DOI: 10.2214/ajr.13.12191.Peer-Reviewed Original ResearchConceptsSize-specific dose estimateStatistically significant correlationDose estimatesBody weightTorso diameterSize-specific doseConsecutive CT examinationsMedian body weightPatient's body weightRadiation dose estimatesSignificant correlationPediatric CTCT examinationsEffective diameterIndividual patientsOverall body weightClinical settingPatientsDoseD(apChildrenAutomated softwareMeasured diameterBodyManual measurements