2024
Telavancin and Cardiac Surgery: Balancing Antimicrobial Efficacy with Coagulation Challenges
Munoz-Acuna R, Wai M, Coopee Z, Asuquo R, Rady A, Montealegre-Gallegos M. Telavancin and Cardiac Surgery: Balancing Antimicrobial Efficacy with Coagulation Challenges. Journal Of Cardiothoracic And Vascular Anesthesia 2024 PMID: 39426857, DOI: 10.1053/j.jvca.2024.09.147.Peer-Reviewed Original ResearchIs There More to POCUS Than the Heart and Lungs in the Parturient—Venous Excess Ultrasound Score?
Munoz-Acuna R, Charchaflieh J, Deshpande R. Is There More to POCUS Than the Heart and Lungs in the Parturient—Venous Excess Ultrasound Score? Anesthesia & Analgesia 2024, 139: e23-e25. PMID: 39151137, DOI: 10.1213/ane.0000000000007100.Peer-Reviewed Original ResearchUltrasonography for Procedural Guidance
Munoz-Acuna R, Leibowitz A, Bose S. Ultrasonography for Procedural Guidance. 2024, 493-507. DOI: 10.1007/978-3-031-45731-9_21.Peer-Reviewed Original ResearchIntensive care unitCare unitEvaluate cardiac functionCritically ill patientsStandard of careSonographic evaluationPelvic contentsCardiac functionExtracorporeal supportAbnormal anatomyVenous structuresLung parenchymaVascular accessIll patientsCritical care unitsClinical practiceUltrasound machineDiagnostic toolUltrasoundUltrasonographyProcedural guidanceA Shocking Discovery Electrostatic Discharge-Induced Pump Failure in an Implantable Left Ventricular Assist Device
Quien M, Paquette D, Montealegre-Gallegos M, Szabo C, Anwer M, Munoz-Acuna R. A Shocking Discovery Electrostatic Discharge-Induced Pump Failure in an Implantable Left Ventricular Assist Device. JACC Case Reports 2024, 29: 102392. PMID: 38912318, PMCID: PMC11190473, DOI: 10.1016/j.jaccas.2024.102392.Peer-Reviewed Original ResearchTricyclic Antidepressants
Munoz-Acuna R, Munoz-Acuna R. Tricyclic Antidepressants. 2024, 395-396. DOI: 10.1093/med/9780197584569.003.0157.Peer-Reviewed Original ResearchTricyclic antidepressantsSide effectsReuptake of noradrenalineTreatment of choiceSpectrum of adverse effectsPotential side effectsCentral nervous systemAlpha-adrenoceptorsAcute painChronic painPerioperative considerationsSupportive treatmentPerioperative periodAbstract AntidepressantsSynaptic cleftPrescribed medicationsNervous systemTreating depressionPresynaptic terminalsAntidepressantsAdverse effectsPainMedicationTreatmentReuptake
2022
Effects of Ketamine Infusion on Breathing and Encephalography in Spontaneously Breathing ICU Patients
Suleiman A, Santer P, Munoz-Acuna R, Hammer M, Schaefer MS, Wachtendorf LJ, Rumyantsev S, Berra L, Chamadia S, Johnson-Akeju O, Baedorf-Kassis EN, Eikermann M. Effects of Ketamine Infusion on Breathing and Encephalography in Spontaneously Breathing ICU Patients. Journal Of Intensive Care Medicine 2022, 38: 299-306. PMID: 35934953, DOI: 10.1177/08850666221119716.Peer-Reviewed Original ResearchConceptsSpontaneous breathing trialKetamine infusionMcg/Inspiratory flowInspiratory workKey secondary endpointProspective interventional studyEnd-expiratory pressurePre-specified time pointsKetamine 10Breathing trialSecondary endpointsPrimary outcomeICU patientsIll patientsMechanical ventilationEsophageal pressureInfusion regimenInterventional studyPropofol sedationRespiratory timingResistive workAirway flowPreclinical studiesElectroencephalographic patternsEchocardiography on Twitter—An #Echofirst Analysis
Munoz-Acuna R, Montealegre-Gallegos M, Mahmood F, Dalia A. Echocardiography on Twitter—An #Echofirst Analysis. Journal Of The American Society Of Echocardiography 2022, 35: 891-892. PMID: 35395391, DOI: 10.1016/j.echo.2022.03.021.Peer-Reviewed Original Research
2021
Extracorporeal Membrane Oxygenation
Munoz-Acuna R, Pannu A. Extracorporeal Membrane Oxygenation. 2021, 27-31. DOI: 10.1201/9781003042136-05.Peer-Reviewed Original ResearchAcute respiratory distress syndromeSevere acute respiratory distress syndromeVV-ECMOVenovenous extracorporeal membrane oxygenation supportExtracorporeal membrane oxygenation supportSevere hypoxemia refractoryVV-ECMO useMembrane oxygenation supportRespiratory distress syndromeExtracorporeal membrane oxygenationARDS trialsHypoxemia refractoryECMO useOxygenation supportRefractory hypoxemiaCohort studyLung injuryDistress syndromeMembrane oxygenationRescue modalityVenous bloodImproved outcomesEarly initiationExtracorporeal therapyECMODelirium
Munoz-Acuna R, O'Gara B. Delirium. 2021, 205-210. DOI: 10.1201/9781003042136-35.Peer-Reviewed Original ResearchIntensive care unitNewer atypical antipsychotic agentsLong-term cognitive functionIncidence of deliriumMechanical ventilation timeNumerous pharmacological strategiesUnderlying medical disorderAtypical antipsychotic agentsDelirium preventionICU lengthCare unitMechanical ventilationVentilation timeClinical trialsPharmacological strategiesSimilar efficacyAntipsychotic agentsMedical disordersDeliriumBehavioral disturbancesSide effectsMental disordersCognitive functionStatistical ManualExcess costsAnalysis of top influencers in critical care medicine “twitterverse” in the COVID-19 era: a descriptive study
Munoz-Acuna R, Leibowitz A, Hayes M, Bose S. Analysis of top influencers in critical care medicine “twitterverse” in the COVID-19 era: a descriptive study. Critical Care 2021, 25: 254. PMID: 34284805, PMCID: PMC8290385, DOI: 10.1186/s13054-021-03691-6.Peer-Reviewed Original ResearchA Retrocardiac Echolucency
Montealegre-Gallegos M, Matyal R, Muñoz-Acuña R, Eichinger C, Walsh DP. A Retrocardiac Echolucency. Journal Of Cardiothoracic And Vascular Anesthesia 2021, 36: 915-917. PMID: 34362642, DOI: 10.1053/j.jvca.2021.06.037.Peer-Reviewed Original ResearchA Case Report on Papillary Muscle Rupture Following Mitral Valve Replacement in the Setting of Previously Undiagnosed Amyloidosis.
Choudhury N, Munoz Acuna R, Chaudhary O, Chu L, VanderLaan P, Mahmood F, Sharkey A. A Case Report on Papillary Muscle Rupture Following Mitral Valve Replacement in the Setting of Previously Undiagnosed Amyloidosis. A&A Practice 2021, 15: e01415. PMID: 33684090, DOI: 10.1213/xaa.0000000000001415.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseAbsence of CADMitral valve replacement surgeryMitral valve replacementValve replacement surgeryLight chain subtypesCardiac involvementValve replacementArtery diseaseCardiopulmonary bypassAmyloid depositionCase reportReplacement surgeryCardiac amyloidosisSubvalvular apparatusPapillary musclesSubsequent pathologyAmyloidosisPatientsIschemiaSurgeryBypassTherapyMortalitySubtypes
2020
Heterotopic caval valve implantation for the management of severe tricuspid regurgitation: a case series
Sharkey A, Acuna R, Belani K, Sharma RK, Chaudhary O, Fatima H, Laham R, Mahmood F. Heterotopic caval valve implantation for the management of severe tricuspid regurgitation: a case series. European Heart Journal - Case Reports 2020, 5: ytaa428. PMID: 33644639, PMCID: PMC7898562, DOI: 10.1093/ehjcr/ytaa428.Peer-Reviewed Original ResearchCaval valve implantationSevere tricuspid regurgitationTricuspid regurgitationSurgical interventionMedical therapyValve implantationSymptomatic severe tricuspid regurgitationMaximal medical therapyPatients surgical interventionCases of patientsRight atrium junctionProgressive symptomsHeart failureSymptom reliefAtrium junctionCase seriesHigh morbidityNon-invasive methodPostoperative haemodynamicsExtensive comorbiditySuccessful dischargePatientsSymptomsTherapyInterventionBacteriemia por Kluyvera cryocrescens
Acuña R, Rodríguez J, Vindas J. Bacteriemia por Kluyvera cryocrescens. Acta Médica Costarricense 2020, 58 DOI: 10.51481/amc.v58i1.913.Peer-Reviewed Original ResearchBOSTN Bundle Intervention for Perioperative Screening and Management of Patients With Suspected Obstructive Sleep Apnea: A Hospital Registry Study.
Raub D, Santer P, Nabel S, Platzbecker K, Munoz-Acuna R, Xu X, Friedrich S, Ramachandran SK, Eikermann M, Sundar E. BOSTN Bundle Intervention for Perioperative Screening and Management of Patients With Suspected Obstructive Sleep Apnea: A Hospital Registry Study. Anesthesia & Analgesia 2020, 130: 1415-1424. PMID: 31283617, DOI: 10.1213/ane.0000000000004294.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaInvasive mechanical ventilationBeth Israel Deaconess Medical CenterHospital registry studyMechanical ventilationRegistry studyPostoperative desaturationSleep apneaPeripheral oxygen saturation measurementsMinutes of extubationNoncardiac surgical casesPostoperative invasive ventilationPreoperative screening toolPostoperative mechanical ventilationKey secondary outcomesDay of surgeryManagement of patientsBody mass indexMultivariable logistic regressionHigh-risk casesLow-risk casesPatient-specific factorsClinical management pathwayOxygen saturation measurementsInvasive ventilation
2019
Effects of laparoscopic vs open abdominal surgery on costs and hospital readmission rate and its effect modification by surgeons’ case volume
Shin TH, Friedrich S, Brat GA, Rudolph MI, Sein V, Munoz-Acuna R, Houle TT, Ferrone CR, Eikermann M. Effects of laparoscopic vs open abdominal surgery on costs and hospital readmission rate and its effect modification by surgeons’ case volume. Surgical Endoscopy 2019, 34: 1-12. PMID: 31659507, DOI: 10.1007/s00464-019-07222-x.Peer-Reviewed Original ResearchConceptsLaparoscopic case volumeOpen abdominal surgeryHospital readmission ratesAbdominal surgeryCase volumeReadmission ratesHospital readmissionAbdominal operationsEffect modificationWound complicationsLaparoscopic approachReadmission riskMethodsThis retrospective cohort studyEffects of laparoscopicIndex hospital admissionReduced hospital readmissionsRetrospective cohort studyHospital admission costsCause hospital readmissionOpen abdominal operationsSurgeon case volumeLaparoscopic abdominal operationsCohort studyHospital admissionAdmission costs