1995
Self-Incorporation of coenzymes by ribozymes
Breaker R, Joyce G. Self-Incorporation of coenzymes by ribozymes. Journal Of Molecular Evolution 1995, 40: 551-558. PMID: 7643406, DOI: 10.1007/bf00160500.Peer-Reviewed Original ResearchConceptsFunctional groupsCoenzyme analoguesAdditional functional groupsChemical functional groupsChemical moietiesTransfer reactionsCovalent attachmentRNA enzymeAbsence of proteinStandard nucleotidesCatalysisCatalytic functionRibozyme activityRNA worldRibozymeMoietyAnaloguesCoenzymeCoA-SHMoleculesReaction
1993
Synthesis and properties of adenosine oligonucleotide analogues containing methylene groups in place of phosphodiester 5'-oxygens.
Breaker R, Gough G, Gilham P. Synthesis and properties of adenosine oligonucleotide analogues containing methylene groups in place of phosphodiester 5'-oxygens. Biochemistry 1993, 32: 9125-8. PMID: 8396423, DOI: 10.1021/bi00086a017.Peer-Reviewed Original Research