2024
Retinal integrity in human babesiosis: a pilot study
Dionne E, Adelman R, Cekic O, Golden M, Moffarah A, Krause P, Farhadian S. Retinal integrity in human babesiosis: a pilot study. BMC Ophthalmology 2024, 24: 310. PMID: 39048971, PMCID: PMC11267664, DOI: 10.1186/s12886-024-03568-6.Peer-Reviewed Original ResearchConceptsEvidence of retinopathyNo study patientRetina of patientsCohort of patientsAbnormal vessel formationComplication of babesiosisRetinal tearsRetinal inflammationRetinal eye examResultsTen patientsRetinal integrityRetinal examinationRetinal bleedingIndirect ophthalmoscopeRetinal abnormalitiesStudy patientsChart reviewCase reportEye examPilot studyPatientsAnimal studiesSmall studyClinical informationHuman babesiosisPreoperative Evaluation of Vitreoretinal Surgery Patients
Chancellor J, Adelman R, Siddiqui M. Preoperative Evaluation of Vitreoretinal Surgery Patients. 2024, 17-25. DOI: 10.1007/978-3-031-47827-7_2.Peer-Reviewed Original ResearchPreoperative evaluationAccurate preoperative evaluationInfluence surgical outcomesEffective preoperative evaluationLens statusVitreous statusFellow eyesIntraocular pressureOptimal patient satisfactionCorneal healthVisual acuityRetinal examinationSurgical successVitreoretinal surgerySurgical outcomesPostoperative outcomesVisual improvementPreoperative assessmentSurgical techniqueSurgical planningPatient characteristicsPotential complicationsPostoperative expectationsPatient satisfactionPatientsOphthalmic care may not align with patient need: An analysis on state-wide patient needs and provider density between 2008 and 2022
Gilson A, Chen Q, Adelman R. Ophthalmic care may not align with patient need: An analysis on state-wide patient needs and provider density between 2008 and 2022. International Journal Of Medical Informatics 2024, 185: 105411. PMID: 38492409, PMCID: PMC11047060, DOI: 10.1016/j.ijmedinf.2024.105411.Peer-Reviewed Original ResearchProvider densityPatient needsDensity of ophthalmologistsOphthalmological careHealthcare availabilityResources patientsPractice locationOphthalmologic termsPatient interestOphthalmic carePatient informationImplementation strategiesPatient's desireCareRetinal specialistsEducational backgroundOphthalmologistsPatientsOphthalmologyTrends dataNeedsHealthcareGoogle Trends dataDemographic elementsProviders
2017
ASSOCIATION BETWEEN THE VITREOMACULAR INTERFACE AND OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS IN WET AGE-RELATED MACULAR DEGENERATION
Ashraf M, Souka A, Adelman RA. ASSOCIATION BETWEEN THE VITREOMACULAR INTERFACE AND OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS IN WET AGE-RELATED MACULAR DEGENERATION. Retina 2017, 37: 1738-1745. PMID: 28005632, DOI: 10.1097/iae.0000000000001423.Peer-Reviewed Original ResearchConceptsType 1 choroidal neovascularizationChoroidal thicknessChoroidal neovascularizationWet AMDVitreomacular adhesionDry AMDVitreomacular interfaceMacular degenerationRetrospective observational cross-sectional studyOptical coherence tomography examinationObservational cross-sectional studyAge-related macular degenerationType of CNVPaired-eye studyMean choroidal thicknessCross-sectional studySignificant differencesOptical coherence tomographyWet AgeSubgroup analysisTomography examinationHeidelberg SpectralisPatientsCoherence tomographyDegeneration characteristicNovel therapeutics for Stargardt disease
Lu LJ, Liu J, Adelman RA. Novel therapeutics for Stargardt disease. Graefe's Archive For Clinical And Experimental Ophthalmology 2017, 255: 1057-1062. PMID: 28285324, DOI: 10.1007/s00417-017-3619-8.Peer-Reviewed Original ResearchConceptsStargardt diseaseVision lossABCA4 geneStem cell transplantationSevere vision lossPromising treatment candidateNovel therapeutic strategiesRetinal pigment epitheliumStem cell therapyVisual acuityStandard treatmentMacular degenerationTreatment candidatesHESC-RPE cellsStargardt patientsTherapeutic strategiesPharmacological agentsPigment epitheliumMacular dystrophyNovel therapeuticsPatientsDiseaseVisual cyclePrevalent formSecond decadeAsymmetric Deep Stromal Keratopathy in a Patient With Multiple Myeloma
Tainsh LT, Coady PA, Sinard JH, Neparidze N, Meskin SW, Adelman RA, Chow J. Asymmetric Deep Stromal Keratopathy in a Patient With Multiple Myeloma. Cornea 2017, 36: 372-374. PMID: 28079685, DOI: 10.1097/ico.0000000000001139.Peer-Reviewed Original ResearchConceptsMultiple myelomaVisual acuityRight eye 2 yearsDeep stromal opacitiesEye 2 yearsPatient's visual acuityDiagnosis of IgGParaproteinemic keratopathyInitial presentationStromal lesionsStromal opacityCase reportHematologic workupMonoclonal gammopathyAsymmetric presentationUnusual casePosterior stromaMyelomaKeratopathyPatientsDiagnosisPresentationLiterature reviewKeratoplastyAcuity
2016
Aflibercept in diabetic macular edema: evaluating efficacy as a primary and secondary therapeutic option
Ashraf M, Souka A, Adelman R, Forster SH. Aflibercept in diabetic macular edema: evaluating efficacy as a primary and secondary therapeutic option. Eye 2016, 30: 1531-1541. PMID: 27564719, PMCID: PMC5177746, DOI: 10.1038/eye.2016.174.Peer-Reviewed Original ResearchConceptsDiabetic macular edemaMacular edemaLarge phase 3 trialsBetter baseline VAEfficacy of afliberceptRole of afliberceptSecondary therapeutic optionsPhase 3 trialProtocol TBaseline VABimonthly regimenNata protocolAnatomic outcomesTherapeutic optionsPoor visionTreatment strategiesPrimary drugAfliberceptDifferent dosesDoseRanibizumabRegimenEdemaPatientsRecent dataHyperacuity Exam Screens for Choroidal Neovascularization in Age-Related Macular Degeneration on a Mobile Device.
Chen JS, Adelman RA. Hyperacuity Exam Screens for Choroidal Neovascularization in Age-Related Macular Degeneration on a Mobile Device. Ophthalmic Surgery Lasers And Imaging Retina 2016, 47: 708-15. PMID: 27548447, DOI: 10.3928/23258160-20160808-03.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChoroidChoroidal NeovascularizationComputers, HandheldCross-Sectional StudiesEquipment DesignFemaleFluorescein AngiographyFundus OculiHumansMacular DegenerationMaleMiddle AgedMobile ApplicationsMonitoring, PhysiologicReproducibility of ResultsTomography, Optical CoherenceVisual AcuityConceptsAge-related macular degenerationChoroidal neovascularizationMacular degenerationSpectral-domain optical coherence tomographySingle-center studyProgression of diseaseOptical coherence tomographyChart reviewTimely treatmentPatientsCoherence tomographyNeovascularizationPatient informationSame dayTreatmentPotential screenFurther dataHuman Research Protection ProgramDegenerationSubspecialistsDiseaseProgression
2015
Idiopathic Epiretinal Membrane and Vitreomacular Traction Preferred Practice Pattern® Guidelines
Folk JC, Adelman RA, Flaxel CJ, Hyman L, Pulido JS, Olsen TW. Idiopathic Epiretinal Membrane and Vitreomacular Traction Preferred Practice Pattern® Guidelines. Ophthalmology 2015, 123: p152-p181. PMID: 26578445, DOI: 10.1016/j.ophtha.2015.10.048.Peer-Reviewed Original ResearchVisual recovery following open globe injury with initial no light perception
Han YS, Kavoussi SC, Adelman RA. Visual recovery following open globe injury with initial no light perception. Clinical Ophthalmology 2015, Volume 9: 1443-1448. PMID: 26316683, PMCID: PMC4540122, DOI: 10.2147/opth.s87852.Peer-Reviewed Original ResearchOpen globe injuriesVisual recoveryGlobe injuriesExact testLight perceptionOcular Trauma ScoreOcular examination findingsCharacteristics of injuriesFisher's exact testUnpaired t-testSecondary enucleationVisual outcomeConsecutive patientsExamination findingsSurgical interventionVisual acuityMean agePrognostic indicatorSingle institutionOphthalmic historyTrauma ScoreInclusion criteriaPatientsSelect casesWound size
2014
Aflibercept in the Treatment of Neovascular Age-Related Macular Degeneration in Previously Treated Patients
Hall LB, Zebardast N, Huang JJ, Adelman RA. Aflibercept in the Treatment of Neovascular Age-Related Macular Degeneration in Previously Treated Patients. Journal Of Ocular Pharmacology And Therapeutics 2014, 30: 346-352. PMID: 24552305, DOI: 10.1089/jop.2013.0188.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAntibodies, Monoclonal, HumanizedBevacizumabFemaleHumansIntravitreal InjectionsMacular DegenerationMaleRanibizumabReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetinaRetrospective StudiesTomography, Optical CoherenceTreatment OutcomeVascular Endothelial Growth Factor AVisual AcuityConceptsAge-related macular degenerationCentral macular thicknessAflibercept injectionsInitial visitMacular degenerationAnti-vascular endothelial growth factor treatmentNeovascular age-related macular degenerationEndothelial growth factor treatmentCentral macular edemaIntraocular pressure increaseSubset of patientsMain outcome measuresOptical coherence tomographyGrowth factor treatmentMacular thicknessNeovascular AgeOcular hypertensionSubmacular fluidVisual outcomeMacular edemaRetrospective studyVisual acuityOutcome measuresStudy populationPatients
2012
Effects of Music Therapy on Intravitreal Injections: A Randomized Clinical Trial
Chen X, Seth RK, Rao VS, Huang JJ, Adelman RA. Effects of Music Therapy on Intravitreal Injections: A Randomized Clinical Trial. Journal Of Ocular Pharmacology And Therapeutics 2012, 28: 414-419. PMID: 22506884, DOI: 10.1089/jop.2011.0257.Peer-Reviewed Original ResearchConceptsMusic therapy groupIntravitreal injectionTherapy groupControl groupOutpatient settingClinical trialsMusic therapyFuture injectionsRandomized clinical trialsMain outcome measuresPost-procedure questionnaireSpielberger State-Trait Anxiety InventorySTAI-S scoresState-Trait Anxiety InventoryTrait Anxiety InventoryRetina clinicMost patientsPain QuestionnaireSafe interventionSubjective painOutcome measuresPatientsPainTherapyGreater decreaseIs Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy?
Prescott CR, Sklar CA, Lesser RL, Adelman RA. Is Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy? Journal Of Neuro-Ophthalmology 2012, 32: 51-53. PMID: 22269947, DOI: 10.1097/wno.0b013e318240596e.Peer-Reviewed Original ResearchConceptsNonarteritic anterior ischemic optic neuropathyAnterior ischemic optic neuropathyIschemic optic neuropathyVisual acuityIntravitreal bevacizumabOptic neuropathyTreatment optionsIntravitreal bevacizumab injectionEffective treatment optionVisual field defectsBevacizumab injectionFellow eyesClinical outcomesRetrospective studyTreatment modalitiesNatural courseField defectsPatientsDecreased acuitySmall seriesAcuityBevacizumabProfound lossVisual fieldNeuropathy
2010
High-Altitude Retinopathy and Optical Coherence Tomography Findings
Seth RK, Adelman RA. High-Altitude Retinopathy and Optical Coherence Tomography Findings. Seminars In Ophthalmology 2010, 25: 13-15. PMID: 20507191, DOI: 10.3109/08820538.2010.481560.Peer-Reviewed Original ResearchConceptsHigh-altitude retinopathyHigh-altitude cerebral edemaCerebral edemaLife-threatening high-altitude cerebral edemaOptical coherence tomography findingsHigh-altitude illnessAltitude cerebral edemaAcute mountain sicknessOptical coherence tomographyReview of literatureTomography findingsOCT findingsCase reportClinical syndromeAltitude illnessMountain sicknessCoherence tomographyEdemaRetinopathyImportant entityPatientsReviewSyndromeIllnessFindings
2009
ASSESSMENT OF OPTIC NERVE CUP-TO-DISK RATIO CHANGES IN PATIENTS RECEIVING MULTIPLE INTRAVITREAL INJECTIONS OF ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS
SETH RK, SALIM S, SHIELDS MB, ADELMAN RA. ASSESSMENT OF OPTIC NERVE CUP-TO-DISK RATIO CHANGES IN PATIENTS RECEIVING MULTIPLE INTRAVITREAL INJECTIONS OF ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS. Retina 2009, 29: 956-959. PMID: 19584654, DOI: 10.1097/iae.0b013e3181a91dfd.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAptamers, NucleotideDrug Therapy, CombinationEyeFollow-Up StudiesFundus OculiHumansInjectionsIntraocular PressureOptic DiskOptic NerveRanibizumabRegional Blood FlowRetrospective StudiesSingle-Blind MethodVascular Endothelial Growth Factor AVitreous BodyConceptsMultiple intravitreal injectionsAnti-VEGF agentsIntraocular pressure riseIntraocular pressure fluctuationIntravitreal injectionMean changeControl groupTransient intraocular pressure riseSignificant differencesDisc ratio changesOptic nerve cupHistory of glaucomaAdditional prospective studiesGrowth factor effectsFellow eyesGlaucoma specialistsOptic nerveProspective studyOptic disc imagesFundus photographsTriamcinolone acetonideInclusion criteriaDisc ratioVertical cupPatientsANGIOID STREAKS IN THALASSEMIA INTERMEDIA: WARNING FOR THROMBOEMBOLIC EVENTS
Vistamehr S, Larrison WI, Adelman RA. ANGIOID STREAKS IN THALASSEMIA INTERMEDIA: WARNING FOR THROMBOEMBOLIC EVENTS. Retinal Cases & Brief Reports 2009, 3: 190-192. PMID: 25391072, DOI: 10.1097/icb.0b013e318162b13a.Peer-Reviewed Original ResearchCentral retinal artery occlusionRetinal artery occlusionPortal vein thrombosisAngioid streaksArtery occlusionVein thrombosisThromboembolic eventsLeft eyeThalassemia intermediaPseudoxanthoma elasticum-like lesionsPanretinal photocoagulationCase reportAnticoagulant factorsFinal visionProphylactic measuresCardiovascular systemThrombosisPatientsFurther assessmentOcclusionΒ-thalassemiaNeovascularizationEyesElastin layersIntermedia
2008
Predicting Response to Glaucoma Therapy in One Eye Based on Response in the Fellow Eye: The Monocular Trial
Chaudhary O, Adelman RA, Shields MB. Predicting Response to Glaucoma Therapy in One Eye Based on Response in the Fellow Eye: The Monocular Trial. JAMA Ophthalmology 2008, 126: 1216-1220. PMID: 18779480, DOI: 10.1001/archopht.126.9.1216.Peer-Reviewed Original ResearchConceptsPrimary open-angle glaucomaIntraocular pressureFellow eyesGlaucoma suspectsSecond eyeFirst eyeSame medicationRetrospective medical record reviewTrue therapeutic effectMedical record reviewOpen-angle glaucomaMedication regimenRecord reviewGlaucoma therapyTherapeutic effectDrug trialsBinocular treatmentMonocular trialMedicationsPatientsAbsolute changeEyesSubsequent responseFurther studiesTrials
2007
Ethambutol Neuroretinopathy
Vistamehr S, Walsh TJ, Adelman RA. Ethambutol Neuroretinopathy. Seminars In Ophthalmology 2007, 22: 141-146. PMID: 17763233, DOI: 10.1080/08820530701457134.Peer-Reviewed Original ResearchConceptsElectrophysiological findingsRetinal pigment epithelial changesAbnormal Arden ratioElectro-oculogram findingsFlame-shaped hemorrhagesPigment epithelial changesFull-field ERGAbnormal wave patternRetinal findingsElectroretinogram findingsMacular edemaClinical featuresEpithelial changesCase reportOcular toxicityPattern ERGArden ratioNeuroretinopathyVisual fieldToxic effectsFindingsEdemaHemorrhagePatientsEthambutolChoroidal Neovascularization Associated with West Nile Virus Chorioretinitis
Seth RK, Stoessel KM, Adelman RA. Choroidal Neovascularization Associated with West Nile Virus Chorioretinitis. Seminars In Ophthalmology 2007, 22: 81-84. PMID: 17564926, DOI: 10.1080/08820530701418375.Peer-Reviewed Original ResearchConceptsWest Nile virus chorioretinitisChoroidal neovascularizationChoroidal Neovascularization AssociatedLate-onset complicationsBest therapeutic optionGood anatomical responseNeovascularization AssociatedDiabetes mellitusLeft eyeIntravitreal injectionTherapeutic optionsChorioretinitisNeovascularizationBevacizumabPatientsInjectionMellitusComplicationsBaseline
2005
The Effectiveness of Isobutyl Cyanoacrylate Tissue Adhesive for the Treatment of Corneal Perforations
Setlik DE, Seldomridge DL, Adelman RA, Semchyshyn TM, Afshari NA. The Effectiveness of Isobutyl Cyanoacrylate Tissue Adhesive for the Treatment of Corneal Perforations. American Journal Of Ophthalmology 2005, 140: 920-921. PMID: 16310475, DOI: 10.1016/j.ajo.2005.04.062.Peer-Reviewed Original Research