2020
Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview
Torres S, Abdullah Z, Brol MJ, Hellerbrand C, Fernandez M, Fiorotto R, Klein S, Königshofer P, Liedtke C, Lotersztajn S, Nevzorova YA, Schierwagen R, Reiberger T, Uschner FE, Tacke F, Weiskirchen R, Trebicka J. Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview. International Journal Of Molecular Sciences 2020, 21: 2027. PMID: 32188134, PMCID: PMC7139397, DOI: 10.3390/ijms21062027.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsLiver cell biologyCell biologyLiver diseaseHepatocellular carcinomaHigh-throughput assaysNon-parenchymal liver cellsSophisticated animal modelsPortal hypertensionLiver pathologyCell isolation techniquesTherapeutic strategiesAnimal modelsStem cellsBiologyPreclinical testingVivo assessmentLiver cellsOrganoid researchVivo methodsNovel opportunitiesDiseaseResearch modalitiesCellsRecent advancesHypertension
2018
Liver diseases in the dish: iPSC and organoids as a new approach to modeling liver diseases
Fiorotto R, Amenduni M, Mariotti V, Fabris L, Spirli C, Strazzabosco M. Liver diseases in the dish: iPSC and organoids as a new approach to modeling liver diseases. Biochimica Et Biophysica Acta (BBA) - Molecular Basis Of Disease 2018, 1865: 920-928. PMID: 30264693, PMCID: PMC6658095, DOI: 10.1016/j.bbadis.2018.08.038.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsLiver diseaseStem cell fieldHepatocyte-like cellsPluripotent stem cellsRegenerative medicineNext-generation toolsSurvival of patientsRecent technological advancesMononuclear blood cellsPotential applicationsGene editingQuality of lifeLiver cell typesDisease modelingCell fieldAdequate cellular modelsLiver transplantationOrgan failureLiver specimensDiseaseStem cellsBlood cellsLiver cellsDrug testingSkin fibroblasts