2019
Molecular Pathway Analysis Indicates a Distinct Metabolic Phenotype in Women With Right-Sided Colon Cancer
Sun Y, Mironova V, Chen Y, Lundh EPF, Zhang Q, Cai Y, Vasiliou V, Zhang Y, Garcia-Milian R, Khan SA, Johnson CH. Molecular Pathway Analysis Indicates a Distinct Metabolic Phenotype in Women With Right-Sided Colon Cancer. Translational Oncology 2019, 13: 42-56. PMID: 31760268, PMCID: PMC6883319, DOI: 10.1016/j.tranon.2019.09.004.Peer-Reviewed Original ResearchRight-sided colon cancerLeft-sided colon cancerColon cancerAnatomical locationTumor tissueAnti-tumor immune responseGene Expression OmnibusImportant predictive markerPoor clinical outcomeTumor anatomical locationClinical outcomesPredictive markerPrimary tumorImmune phenotypeDistinct metabolic phenotypesImmune responseLower incidenceTreatment responseSex-specific differencesMolecular pathway analysisClinical importanceCancerProtein kinase alpha subunitBiotechnology Information Gene Expression OmnibusWomen
2018
Prioritization of reproductive toxicants in unconventional oil and gas operations using a multi-country regulatory data-driven hazard assessment
Inayat-Hussain SH, Fukumura M, Aziz A, Jin CM, Jin LW, Garcia-Milian R, Vasiliou V, Deziel NC. Prioritization of reproductive toxicants in unconventional oil and gas operations using a multi-country regulatory data-driven hazard assessment. Environment International 2018, 117: 348-358. PMID: 29793188, DOI: 10.1016/j.envint.2018.05.010.Peer-Reviewed Original ResearchConceptsReproductive toxicantsUOG chemicalsReproductive toxicityStringent classificationAdverse birth outcomesPotential etiologic agentsGerm cell mutagenicityMultiple adverse effectsPotential public health riskBirth outcomesRegulatory agency databasesEpidemiologic studiesEtiologic agentReproductive healthScoring systemPublic health riskSafe alternativeAdverse effectsHazard identificationDevelopmental toxicantsHazard scoreCytoscape analysisExposure assessmentCancerHealth risks