Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction A Study-Level Pooled Analysis
Pandey A, Khera R, Park B, Haykowsky M, Borlaug BA, Lewis GD, Kitzman DW, Butler J, Berry JD. Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction A Study-Level Pooled Analysis. JACC Heart Failure 2018, 6: 117-126. PMID: 29413366, PMCID: PMC8135913, DOI: 10.1016/j.jchf.2017.10.014.Peer-Reviewed Original ResearchConceptsPulmonary capillary wedge pressureCapillary wedge pressurePeak oxygen uptakePooled analysisWedge pressureEchocardiographic parametersHeart failureExercise intoleranceExaggerated increaseReserve parametersControl groupLower peak oxygen uptakeRelative impairmentStroke volume reserveOxygen uptakeChronic HFpEFHemodynamic reserveExercise toleranceExercise capacityEjection fractionChronotropic reserveControl subjectsCardinal manifestationsHFpEFSignificant abnormalities