2014
“Inflammation and arterial stiffness in humans”
Jain S, Khera R, Corrales–Medina V, Townsend RR, Chirinos JA. “Inflammation and arterial stiffness in humans”. Atherosclerosis 2014, 237: 381-390. PMID: 25463062, DOI: 10.1016/j.atherosclerosis.2014.09.011.Peer-Reviewed Original ResearchConceptsPrimary inflammatory diseaseArterial stiffnessArterial stiffeningInflammatory diseasesPrimary inflammatory conditionsAnti-inflammatory interventionsRole of inflammationAnti-inflammatory therapyEffect of statinsEffects of inflammationPotential therapeutic targetCardiovascular morbiditySubclinical inflammationInflammatory conditionsGeneral populationTherapeutic targetInflammationEstablished markerNormal adultsPotential mechanismsDiseaseHypertensionMorbidityStatinsArtery
2012
Membrane-Bound Complement Regulatory Proteins as Biomarkers and Potential Therapeutic Targets for SLE
Das N, Biswas B, Khera R. Membrane-Bound Complement Regulatory Proteins as Biomarkers and Potential Therapeutic Targets for SLE. Advances In Experimental Medicine And Biology 2012, 735: 55-81. PMID: 23402019, DOI: 10.1007/978-1-4614-4118-2_4.Peer-Reviewed Original ResearchConceptsComplement regulatory proteinsMembrane-bound complement regulatory proteinsTherapeutic targetDisease activityAutoimmune disordersAmerican Rheumatology AssociationAntidouble-stranded DNADisease activity markersSLE disease activitySystemic autoimmune disorderSystemic lupus erythematosusPotential therapeutic targetGene knockout miceLevels of DAFAntinuclear antibodiesLupus erythematosusMultiorgan involvementRheumatology AssociationInflammatory disordersReproductive ageActivity markersNoninvasive biomarkersDiagnostic criteriaKnockout miceSLE