In vivo 1H MR spectroscopic imaging and difusion weighted mri in experimental hydrocephalus
Braun K, de Graaf R, Vandertop W, Gooskens R, Tulleken K, Nicolay K. In vivo 1H MR spectroscopic imaging and difusion weighted mri in experimental hydrocephalus. Magnetic Resonance In Medicine 1998, 40: 832-839. PMID: 9840827, DOI: 10.1002/mrm.1910400608.Peer-Reviewed Original ResearchConceptsMR spectroscopic imagingExperimental hydrocephalusApparent diffusion coefficientInjection of kaolinIschemic metabolic changesWhite matter edemaDegree of ventriculomegalyHigher lactate levelsGray matter regionsProgressive ventriculomegalyCerebral edemaCerebral ischemiaVentricular enlargementHydrocephalic ratsKaolin injectionRat modelAccumulation of lactateDifferent time coursesLactate levelsCerebrospinal fluidCisterna magnaVentricular expansionHydrocephalusWhole brainSpectroscopic imaging