2014
Confluence of Depression and Acute Psychological Stress Among Patients With Stable Coronary Heart Disease: Effects on Myocardial Perfusion
Burg MM, Meadows J, Shimbo D, Davidson KW, Schwartz JE, Soufer R. Confluence of Depression and Acute Psychological Stress Among Patients With Stable Coronary Heart Disease: Effects on Myocardial Perfusion. Journal Of The American Heart Association 2014, 3: e000898. PMID: 25359402, PMCID: PMC4338683, DOI: 10.1161/jaha.114.000898.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedChi-Square DistributionChronic DiseaseConnecticutCoronary CirculationCoronary DiseaseDepressionFemaleHemodynamicsHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial Perfusion ImagingOdds RatioPredictive Value of TestsPsychiatric Status Rating ScalesRecurrenceRisk FactorsSeverity of Illness IndexStress, PsychologicalTomography, Emission-Computed, Single-PhotonConceptsAcute psychological stressMyocardial perfusionPsychological stressDepressed rangeNormal rangeAcute coronary syndrome (ACS) recurrenceSelective serotonin reuptake inhibitor medicationsStable coronary heart diseaseCoronary heart disease patientsSerotonin reuptake inhibitor medicationsImpaired myocardial perfusionTomography myocardial perfusionCoronary heart diseaseMortality risk factorsOptimal medical careHigh normal rangeReuptake inhibitor medicationsHeart disease patientsBeck Depression InventorySingle photon emissionACS recurrenceCHD prognosisInhibitor medicationVascular mechanismsMeasures of depression
2003
Simultaneous assessment of myocardial perfusion and function during mental stress in patients with chronic coronary artery disease
Arrighi JA, Burg M, Cohen IS, Soufer R. Simultaneous assessment of myocardial perfusion and function during mental stress in patients with chronic coronary artery disease. Journal Of Nuclear Cardiology 2003, 10: 267-274. PMID: 12794625, DOI: 10.1016/s1071-3581(02)43235-7.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingChronic coronary artery diseaseLeft ventricular dysfunctionVentricular dysfunctionCoronary artery diseaseReversible perfusion defectsPerfusion defectsArtery diseaseVentricular functionMyocardial perfusionNew regional wall motion abnormalitiesSestamibi single-photon emissionPharmacologic stress myocardial perfusion imagingStress myocardial perfusion imagingGlobal left ventricular dysfunctionRegional wall motion abnormalitiesResultsTwenty-eight patientsLeft ventricular functionWall motion abnormalitiesTomography (SPECT) MPIMyocardial perfusion defectsRegional wall motionCircumferential profile analysisSingle photon emissionSimultaneous assessment
2002
Correlation of myocardial p-(123)I-iodophenylpentadecanoic acid retention with (18)F-FDG accumulation during experimental low-flow ischemia.
Shi CQ, Young LH, Daher E, DiBella EV, Liu YH, Heller EN, Zoghbi S, Wackers FJ, Soufer R, Sinusas AJ. Correlation of myocardial p-(123)I-iodophenylpentadecanoic acid retention with (18)F-FDG accumulation during experimental low-flow ischemia. Journal Of Nuclear Medicine 2002, 43: 421-31. PMID: 11884504.Peer-Reviewed Original Research
2000
Myocardial blood-flow response during mental stress in patients with coronary artery disease
Arrighi J, Burg M, Cohen I, Kao A, Pfau S, Caulin-Glaser T, Zaret B, Soufer R. Myocardial blood-flow response during mental stress in patients with coronary artery disease. The Lancet 2000, 356: 310-311. PMID: 11071190, DOI: 10.1016/s0140-6736(00)02510-1.Peer-Reviewed Original ResearchPersistent Changes in Myocardial Glucose Metabolism In Vivo During Reperfusion of a Limited-Duration Coronary Occlusion
McNulty P, Jagasia D, Cline G, Ng C, Whiting J, Garg P, Shulman G, Soufer R. Persistent Changes in Myocardial Glucose Metabolism In Vivo During Reperfusion of a Limited-Duration Coronary Occlusion. Circulation 2000, 101: 917-922. PMID: 10694532, DOI: 10.1161/01.cir.101.8.917.Peer-Reviewed Original ResearchConceptsCoronary occlusionGlucose metabolismPostischemic stunningAnterolateral left ventricleHeart glucose metabolismCoronary artery occlusionRegional glucose metabolismMyocardial glucose metabolismRegional myocardial ischemiaRegional mechanical functionRapid reperfusionReversible coronary occlusionArtery occlusionMyocardial ischemiaIntact ratsPreferential shuntingBlood flowReperfusionTracer uptakeLeft ventricleGlycogen depletionMetabolic signaturesOcclusionPersistent changesSustained changes
1998
Myocardial viability: Seeking relevance and redefinition
Arrighi J, Soufer R. Myocardial viability: Seeking relevance and redefinition. Journal Of Nuclear Cardiology 1998, 5: 629-633. PMID: 9869486, DOI: 10.1016/s1071-3581(98)90118-0.Peer-Reviewed Original Research
1992
Left Ventricular Diastolic Function during Positive End-expiratory Pressure: Impact of Right Ventricular Ischemia and Ventricular Interaction
Schulman D, Biondi J, Zohgbi S, Cecchetti A, Zaret B, Soufer R. Left Ventricular Diastolic Function during Positive End-expiratory Pressure: Impact of Right Ventricular Ischemia and Ventricular Interaction. American Journal Of Respiratory And Critical Care Medicine 1992, 145: 515-521. PMID: 1546829, DOI: 10.1164/ajrccm/145.3.515.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureLeft ventricular end-diastolic pressure-volume relationEnd-expiratory pressureRCA occlusionEnd-diastolic volumeEnd-systolic volumeCardiac outputEjection fractionRight ventricularAddition of PEEPRight coronary artery occlusionEnd-diastolic pressure-volume relationRight ventricular ischemiaVentricular diastolic functionVentricular ejection fractionCoronary artery occlusionArtery occlusionAtrial pressureDiastolic functionPressure-volume relationVentricular ischemiaAnesthetized dogsVentricular interactionLV volumesRVEDV
1990
Coronary Flow Limits Right Ventricular Performance during Positive End-expiratory Pressure
Schulman D, Biondi J, Zohgbi S, Zaret B, Soufer R. Coronary Flow Limits Right Ventricular Performance during Positive End-expiratory Pressure. American Journal Of Respiratory And Critical Care Medicine 1990, 141: 1531-1537. PMID: 2190508, DOI: 10.1164/ajrccm/141.6.1531.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCardiac OutputCoronary CirculationCoronary DiseaseDogsFemaleMaleMyocardial ContractionPositive-Pressure RespirationStroke VolumeThermodilutionConceptsPositive end-expiratory pressureRight ventricular ejection fractionH2O positive end-expiratory pressureEnd-diastolic volumeRight ventricular performanceMyocardial blood flowRCA occlusionEnd-expiratory pressureBlood flowVentricular performanceRight ventricular myocardial blood flowRight coronary blood flowRight coronary artery occlusionVentricular myocardial blood flowVentricular ejection fractionCoronary blood flowCoronary artery occlusionEnd-ejection volumeArtery occlusionEjection fractionPressure-volume relationRCA flowExperimental modelOcclusionPositron emission tomography and the quantitative assesment of regional myocardial blood flow
Soufer R, Zaret B. Positron emission tomography and the quantitative assesment of regional myocardial blood flow. Journal Of The American College Of Cardiology 1990, 15: 128-130. PMID: 2295721, DOI: 10.1016/0735-1097(90)90187-t.Peer-Reviewed Original Research