2003
Simultaneous assessment of myocardial perfusion and function during mental stress in patients with chronic coronary artery disease
Arrighi JA, Burg M, Cohen IS, Soufer R. Simultaneous assessment of myocardial perfusion and function during mental stress in patients with chronic coronary artery disease. Journal Of Nuclear Cardiology 2003, 10: 267-274. PMID: 12794625, DOI: 10.1016/s1071-3581(02)43235-7.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingChronic coronary artery diseaseLeft ventricular dysfunctionVentricular dysfunctionCoronary artery diseaseReversible perfusion defectsPerfusion defectsArtery diseaseVentricular functionMyocardial perfusionNew regional wall motion abnormalitiesSestamibi single-photon emissionPharmacologic stress myocardial perfusion imagingStress myocardial perfusion imagingGlobal left ventricular dysfunctionRegional wall motion abnormalitiesResultsTwenty-eight patientsLeft ventricular functionWall motion abnormalitiesTomography (SPECT) MPIMyocardial perfusion defectsRegional wall motionCircumferential profile analysisSingle photon emissionSimultaneous assessment
1997
Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both
Arrighi J, Ng C, Dey H, Wackers F, Soufer R. Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both. The American Journal Of Cardiology 1997, 80: 1007-1013. PMID: 9352969, DOI: 10.1016/s0002-9149(97)00594-8.Peer-Reviewed Original ResearchConceptsCoronary artery diseasePositron emission tomographyLV dysfunctionArtery diseaseGroup 2Myocardial viabilityGroup 1Ejection fractionModerate coronary artery diseaseEmission tomographyModerate LV dysfunctionSevere LV dysfunctionStable angina pectorisLV ejection fractionGlobal LV dysfunctionAccuracy of technetiumSingle photon emissionSemiquantitative SPECTVentricular dysfunctionViability detectionAngina pectorisVentricular functionReduced perfusionSestamibi SPECTMyocardial infarct
1995
Left ventricular diastolic function: Physiology, methods of assessment, and clinical significance
Arrighi J, Soufer R. Left ventricular diastolic function: Physiology, methods of assessment, and clinical significance. Journal Of Nuclear Cardiology 1995, 2: 525-543. PMID: 9420835, DOI: 10.1016/s1071-3581(05)80045-5.Peer-Reviewed Original ResearchConceptsDiastolic functionVentricular fillingHeart failureElevated pulmonary venous pressureNormal systolic ventricular functionSystolic ventricular functionNormal systolic functionCongestive heart failurePulmonary venous pressureCoronary artery diseaseCalcium channel blockersEarly ventricular fillingHealthy elderly subjectsMitral valve closureBeta blockersSystolic functionArtery diseaseCardiac catheterizationSuch patientsValvular diseaseVenous pressureVentricular functionOptimal therapyRadionuclide angiographyMyocardial compliance
1991
Radionuclide Evaluation of Ventricular Performance in Congestive Heart Failure: An Overview
Zaret B, Soufer R. Radionuclide Evaluation of Ventricular Performance in Congestive Heart Failure: An Overview. 1991, 89-98. DOI: 10.1007/978-3-642-58231-8_10.Peer-Reviewed Original Research
1989
Differing responses in right and left ventricular filling, loading and volumes during positive end-expiratory pressure
Schulman D, Biondi J, Matthay R, Zaret B, Soufer R. Differing responses in right and left ventricular filling, loading and volumes during positive end-expiratory pressure. The American Journal Of Cardiology 1989, 64: 772-777. PMID: 2679024, DOI: 10.1016/0002-9149(89)90763-7.Peer-Reviewed Original ResearchConceptsPeak filling rateEnd-diastolic volumeLV end-diastolic volumeEjection fractionLeft ventricularCardiac outputRV volumesLV volumesPositive end-expiratory pressure (PEEP) applicationRight ventricular ejection fractionRV end-diastolic volumePositive end-expiratory pressureGroup 1 patientsLow cardiac outputSystemic vascular resistanceVentricular ejection fractionCoronary artery diseaseLV ejection fractionRV ejection fractionEnd-expiratory pressureFilling rateVascular resistanceArtery diseaseBlood pressureVentricular function
1988
The Effect of Incremental Positive End-Expiratory Pressure on Right Ventricular Hemodynamics and Ejection Fraction.
Biondi JW, Schulman DS, Soufer R, Matthay RA, Hines RL, Kay HR, Barash PG. The Effect of Incremental Positive End-Expiratory Pressure on Right Ventricular Hemodynamics and Ejection Fraction. Anesthesia & Analgesia 1988, 67: 144. PMID: 3277479, DOI: 10.1213/00000539-198802000-00007.Peer-Reviewed Original ResearchConceptsH2O positive end-expiratory pressurePositive end-expiratory pressureRight ventricular end-diastolic volume indexRight ventricular end-systolic volume indexEnd-systolic volume indexRight ventricular ejection fractionEnd-expiratory pressureVentricular end-diastolic volume indexVentricular end-systolic volume indexIncremental positive end-expiratory pressureEnd-diastolic volume indexVentricular ejection fractionEjection fractionVolume indexRV end-systolic volume indexSystolic pressure-volume relationRight ventricular hemodynamicsRight ventricular functionRight ventricular contractilityRV contractilityRV hemodynamicsSystolic pressureVentricular functionVentricular contractilityPressure-volume relationEffect of positive end-expiratory pressure on right ventricular performance Importance of baseline right ventricular function
Schulman D, Biondi J, Matthay R, Barash P, Zaret B, Soufer R. Effect of positive end-expiratory pressure on right ventricular performance Importance of baseline right ventricular function. The American Journal Of Medicine 1988, 84: 57-67. PMID: 3276186, DOI: 10.1016/0002-9343(88)90009-5.Peer-Reviewed Original ResearchConceptsRight ventricular ejection fractionBaseline right ventricular ejection fractionVentricular ejection fractionBaseline right ventricular functionRight ventricular functionEjection fractionContractile functionVentricular functionVentricular volumePositive end-expiratory pressure (PEEP) applicationSystolic pressure-volume relationPositive end-expiratory pressureRight ventricular contractile functionSystolic volume relationRight heart pressuresEffects of PEEPVentricular contractile functionEnd-expiratory pressureEnd-systolic volumeRight ventricular volumeH2O PEEPHeart pressuresPEEP levelsPressure-volume relationCardiac output
1985
Intact systolic left ventricular function in clinical congestive heart failure
Soufer R, Wohlgelernter D, Vita N, Amuchestegui M, Sostman H, Berger H, Zaret B. Intact systolic left ventricular function in clinical congestive heart failure. The American Journal Of Cardiology 1985, 55: 1032-1036. PMID: 3984863, DOI: 10.1016/0002-9149(85)90741-6.Peer-Reviewed Original ResearchConceptsClinical congestive heart failureIntact systolic functionCongestive heart failurePeak filling rateSystolic functionDiastolic functionHeart failureClinical CHFSignificant left ventricular systolic dysfunctionLeft ventricular systolic dysfunctionAbnormal diastolic functionVentricular systolic dysfunctionCoronary artery diseaseTreatment of patientsOptimal therapeutic strategyNuclear cardiology laboratoryCHF scoreDiastolic dysfunctionSystemic hypertensionSystolic dysfunctionArtery diseaseVentricular functionRadionuclide evaluationSignificant abnormalitiesClinical impression