2011
Cardiac repolarization instability during psychological stress in patients with ventricular arrhythmias
Abisse SS, Lampert R, Burg M, Soufer R, Shusterman V. Cardiac repolarization instability during psychological stress in patients with ventricular arrhythmias. Journal Of Electrocardiology 2011, 44: 678-683. PMID: 21920534, PMCID: PMC3200452, DOI: 10.1016/j.jelectrocard.2011.07.019.Peer-Reviewed Original ResearchConceptsSubsequent ventricular tachyarrhythmiasVentricular tachyarrhythmiasGroup 2Group 1Life-threatening ventricular tachyarrhythmiasPsychological stressSubsequent arrhythmic eventsAutonomic nervous system activityNervous system activityCardiac repolarization instabilityICD implantationVentricular arrhythmiasArrhythmic eventsQT intervalRepolarization responseCardiac repolarizationHeart ratePatientsT-wave areaPsychological stressorsMental stressRepolarization instabilityCardiac physiologySystem activitySignificant differences
2009
Anger-Induced T-Wave Alternans Predicts Future Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators
Lampert R, Shusterman V, Burg M, McPherson C, Batsford W, Goldberg A, Soufer R. Anger-Induced T-Wave Alternans Predicts Future Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators. Journal Of The American College Of Cardiology 2009, 53: 774-778. PMID: 19245968, PMCID: PMC3979284, DOI: 10.1016/j.jacc.2008.10.053.Peer-Reviewed Original ResearchConceptsVentricular tachycardia/ventricular fibrillationFuture ventricular arrhythmiasT-wave alternansVentricular arrhythmiasVentricular fibrillationSpontaneous ventricular tachycardia/ventricular fibrillationHigher TWAImplantable cardioverter defibrillatorEjection fractionHighest quartileTWA testingWide QRSClinical arrhythmiaAmbulatory electrocardiographyLowest quartileFuture arrhythmiasSudden deathCardioverter defibrillatorClinical roleMultivariable regressionPatientsArrhythmiasRepolarization instabilityStress protocolSignificant predictors
2007
Implantable Cardioverter‐Defibrillator Shocks Increase T‐Wave Alternans
LAMPERT R, SOUFER R, McPHERSON CA, BATSFORD WP, TIRADO S, EARLEY C, GOLDBERG A, SHUSTERMAN V. Implantable Cardioverter‐Defibrillator Shocks Increase T‐Wave Alternans. Journal Of Cardiovascular Electrophysiology 2007, 18: 512-517. PMID: 17428273, DOI: 10.1111/j.1540-8167.2007.00787.x.Peer-Reviewed Original ResearchConceptsRepolarization instabilityQRS duration changesImplantable defibrillator shocksAmbulatory ECG monitoringT-wave alternansNorepinephrine levelsCoronary diseaseICD shocksSympathetic stimulationVentricular arrhythmiasInduced arrhythmiasVentricular arrhythmogenesisDefibrillator shocksQRS durationQT intervalSedated stateAdequate preClinical implicationsDefibrillation therapyECG monitoringRR intervalsHolter dataBaseline statePatientsArrhythmias
2005
Effects of Psychologic Stress on Repolarization and Relationship to Autonomic and Hemodynamic Factors
LAMPERT R, SHUSTERMAN V, BURG MM, LEE FA, EARLEY C, GOLDBERG A, MCPHERSON CA, BATSFORD WP, SOUFER R. Effects of Psychologic Stress on Repolarization and Relationship to Autonomic and Hemodynamic Factors. Journal Of Cardiovascular Electrophysiology 2005, 16: 372-377. PMID: 15828878, DOI: 10.1046/j.1540-8167.2005.40580.x.Peer-Reviewed Original ResearchConceptsT-wave alternansMental stressVentricular arrhythmiasPsychological stressAmbulatory ECG monitoringT-wave amplitudePathophysiologic linkSusceptible patientsSystolic BPRepolarization indicesAlters indicesPsychologic stressRepolarization changesSudden deathPatientsHemodynamic factorsT-wave areaStress protocolECG monitoringArrhythmiasPhysiologic pathwaysRepolarizationMyocardial heterogeneityICDHr