2011
Autonomic Contribution to Endothelin-1 Increase during Laboratory Anger-Recall Stress in Patients with Coronary Artery Disease
Burg MM, Soufer A, Lampert R, Collins D, Soufer R. Autonomic Contribution to Endothelin-1 Increase during Laboratory Anger-Recall Stress in Patients with Coronary Artery Disease. Molecular Medicine 2011, 17: 495-501. PMID: 21267513, PMCID: PMC3105151, DOI: 10.2119/molmed.2010.00083.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseEndothelin-1Parasympathetic activityArtery diseaseAutonomic contributionsChronic stable coronary artery diseaseStable coronary artery diseaseCholinergic antiinflammatory pathwayLaboratory stressCoronary plaque ruptureEndothelin-1 increaseSignificant odds ratioEndothelial cell functionCardiac eventsEndothelial dysfunctionIndwelling catheterAutonomic factorsSympathetic activityAntiinflammatory pathwayAutonomic influencesAutonomic toneOdds ratioPlaque ruptureParasympathetic withdrawalHemodynamic monitor
2010
Depression Predicts Elevated Endothelin-1 in Patients With Coronary Artery Disease
Burg MM, Martens EJ, Collins D, Soufer R. Depression Predicts Elevated Endothelin-1 in Patients With Coronary Artery Disease. Psychosomatic Medicine 2010, 73: 2-6. PMID: 20947777, PMCID: PMC3016462, DOI: 10.1097/psy.0b013e3181fdfb25.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseEndothelin-1Beck Depression InventoryBDI scoresLogistic regression modelsArtery diseaseLog-transformed continuous variableRisk thresholdElevated endothelin-1ET-1 elevationET-1 levelsEvent-free survivalMorning blood samplesWorse depression symptomsDepression symptom severityEarly morbidityRegression modelsPoor survivalPlaque ruptureAdjusted modelBlood samplesDepressive symptomsDepression severityDepression symptomsDepression InventoryTendency to Angry Rumination Predicts Stress-Provoked Endothelin-1 Increase in Patients With Coronary Artery Disease
Fernandez AB, Soufer R, Collins D, Soufer A, Ranjbaran H, Burg MM. Tendency to Angry Rumination Predicts Stress-Provoked Endothelin-1 Increase in Patients With Coronary Artery Disease. Psychosomatic Medicine 2010, 72: 348-353. PMID: 20368479, PMCID: PMC2872076, DOI: 10.1097/psy.0b013e3181d71982.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseET-1 increaseET-1Chronic stable coronary heart diseaseStable coronary heart diseaseMultivariate logistic regression modelET-1 elevationAcute coronary syndromeHistory of diabetesRate-pressure productCoronary artery diseaseEndothelin-1 increaseLogistic regression modelsCoronary syndromeArtery diseaseBeta blockersPotential confoundersPressure productHeart diseasePlaque ruptureBlood samplesPatientsAngry ruminationNitric oxideStress protocol