2009
Anger-Induced T-Wave Alternans Predicts Future Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators
Lampert R, Shusterman V, Burg M, McPherson C, Batsford W, Goldberg A, Soufer R. Anger-Induced T-Wave Alternans Predicts Future Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators. Journal Of The American College Of Cardiology 2009, 53: 774-778. PMID: 19245968, PMCID: PMC3979284, DOI: 10.1016/j.jacc.2008.10.053.Peer-Reviewed Original ResearchConceptsVentricular tachycardia/ventricular fibrillationFuture ventricular arrhythmiasT-wave alternansVentricular arrhythmiasVentricular fibrillationSpontaneous ventricular tachycardia/ventricular fibrillationHigher TWAImplantable cardioverter defibrillatorEjection fractionHighest quartileTWA testingWide QRSClinical arrhythmiaAmbulatory electrocardiographyLowest quartileFuture arrhythmiasSudden deathCardioverter defibrillatorClinical roleMultivariable regressionPatientsArrhythmiasRepolarization instabilityStress protocolSignificant predictors
1997
Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both
Arrighi J, Ng C, Dey H, Wackers F, Soufer R. Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both. The American Journal Of Cardiology 1997, 80: 1007-1013. PMID: 9352969, DOI: 10.1016/s0002-9149(97)00594-8.Peer-Reviewed Original ResearchConceptsCoronary artery diseasePositron emission tomographyLV dysfunctionArtery diseaseGroup 2Myocardial viabilityGroup 1Ejection fractionModerate coronary artery diseaseEmission tomographyModerate LV dysfunctionSevere LV dysfunctionStable angina pectorisLV ejection fractionGlobal LV dysfunctionAccuracy of technetiumSingle photon emissionSemiquantitative SPECTVentricular dysfunctionViability detectionAngina pectorisVentricular functionReduced perfusionSestamibi SPECTMyocardial infarct
1995
Comparison of sestamibi single-photon emission computed tomography with positron emission tomography for estimating left ventricular myocarclial viability
Soufer R, Dey H, Ng C, Zaret B. Comparison of sestamibi single-photon emission computed tomography with positron emission tomography for estimating left ventricular myocarclial viability. The American Journal Of Cardiology 1995, 75: 1214-1219. PMID: 7778542, DOI: 10.1016/s0002-9149(99)80765-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCoronary DiseaseDeoxyglucoseFluorine RadioisotopesFluorodeoxyglucose F18HumansMaleMiddle AgedMyocardial ContractionRadionuclide VentriculographyStroke VolumeTechnetium Tc 99m SestamibiTomography, Emission-ComputedTomography, Emission-Computed, Single-PhotonVentricular Function, LeftConceptsPositron emission tomographySestamibi single-photon emissionSingle photon emissionCoronary artery diseaseMyocardial viabilityInferior wallArtery diseaseEmission tomographyFDG positron emission tomographySubset of patientsRegional ejection fractionDiscordant segmentsNonviable segmentsEjection fractionMethoxyisobutyl isonitrileRadionuclide ventriculographySestamibi protocolBlood flowMyocardial segmentsPatientsViable segmentsFluorodeoxyglucoseMIBITomographyDisease
1993
Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease
Burg M, Jain D, Soufer R, Kerns R, Zaret B. Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease. Journal Of The American College Of Cardiology 1993, 22: 440-448. PMID: 8335813, DOI: 10.1016/0735-1097(93)90048-6.Peer-Reviewed Original ResearchConceptsSilent left ventricular dysfunctionLeft ventricular dysfunctionCoronary artery diseaseVentricular dysfunctionArtery diseaseBlood pressureChronic stable coronary artery diseaseStable coronary artery diseaseStress thallium-201 imagingMental stressGroup I patientsSilent myocardial ischemiaThallium-201 imagingAbsence of symptomsSerial radionuclide ventriculographyStructured interviewsNonischemic groupEjection fractionI patientsPsychological factorsVentricular indexRadionuclide ventriculographyClinical indicesMyocardial ischemiaReversible defects
1992
Long-term outcome in patients with congestive heart failure and intact systolic left ventricular performance
Setaro J, Soufer R, Remetz M, Perlmutter R, Zaret B. Long-term outcome in patients with congestive heart failure and intact systolic left ventricular performance. The American Journal Of Cardiology 1992, 69: 1212-1216. PMID: 1575193, DOI: 10.1016/0002-9149(92)90938-u.Peer-Reviewed Original ResearchConceptsCongestive heart failureLV systolic functionLV ejection fractionLong-term outcomesThird heart soundCardiovascular eventsCardiovascular mortalitySystolic functionEjection fractionHeart failurePulmonary edemaAverage LV ejection fractionRecurrent congestive heart failureNormal LV systolic functionLeft ventricular systolic performanceSame favorable prognosisLV diastolic dysfunctionAcute pulmonary edemaFuture cardiovascular eventsHypertensive heart diseaseVentricular systolic performanceCoronary artery diseaseHeart soundNoncardiovascular mortalityCardiovascular morbidityLeft Ventricular Diastolic Function during Positive End-expiratory Pressure: Impact of Right Ventricular Ischemia and Ventricular Interaction
Schulman D, Biondi J, Zohgbi S, Cecchetti A, Zaret B, Soufer R. Left Ventricular Diastolic Function during Positive End-expiratory Pressure: Impact of Right Ventricular Ischemia and Ventricular Interaction. American Journal Of Respiratory And Critical Care Medicine 1992, 145: 515-521. PMID: 1546829, DOI: 10.1164/ajrccm/145.3.515.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureLeft ventricular end-diastolic pressure-volume relationEnd-expiratory pressureRCA occlusionEnd-diastolic volumeEnd-systolic volumeCardiac outputEjection fractionRight ventricularAddition of PEEPRight coronary artery occlusionEnd-diastolic pressure-volume relationRight ventricular ischemiaVentricular diastolic functionVentricular ejection fractionCoronary artery occlusionArtery occlusionAtrial pressureDiastolic functionPressure-volume relationVentricular ischemiaAnesthetized dogsVentricular interactionLV volumesRVEDV
1990
Coronary Flow Limits Right Ventricular Performance during Positive End-expiratory Pressure
Schulman D, Biondi J, Zohgbi S, Zaret B, Soufer R. Coronary Flow Limits Right Ventricular Performance during Positive End-expiratory Pressure. American Journal Of Respiratory And Critical Care Medicine 1990, 141: 1531-1537. PMID: 2190508, DOI: 10.1164/ajrccm/141.6.1531.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureRight ventricular ejection fractionH2O positive end-expiratory pressureEnd-diastolic volumeRight ventricular performanceMyocardial blood flowRCA occlusionEnd-expiratory pressureBlood flowVentricular performanceRight ventricular myocardial blood flowRight coronary blood flowRight coronary artery occlusionVentricular myocardial blood flowVentricular ejection fractionCoronary blood flowCoronary artery occlusionEnd-ejection volumeArtery occlusionEjection fractionPressure-volume relationRCA flowExperimental modelOcclusion
1989
Differing responses in right and left ventricular filling, loading and volumes during positive end-expiratory pressure
Schulman D, Biondi J, Matthay R, Zaret B, Soufer R. Differing responses in right and left ventricular filling, loading and volumes during positive end-expiratory pressure. The American Journal Of Cardiology 1989, 64: 772-777. PMID: 2679024, DOI: 10.1016/0002-9149(89)90763-7.Peer-Reviewed Original ResearchConceptsPeak filling rateEnd-diastolic volumeLV end-diastolic volumeEjection fractionLeft ventricularCardiac outputRV volumesLV volumesPositive end-expiratory pressure (PEEP) applicationRight ventricular ejection fractionRV end-diastolic volumePositive end-expiratory pressureGroup 1 patientsLow cardiac outputSystemic vascular resistanceVentricular ejection fractionCoronary artery diseaseLV ejection fractionRV ejection fractionEnd-expiratory pressureFilling rateVascular resistanceArtery diseaseBlood pressureVentricular function
1988
The Effect of Incremental Positive End-Expiratory Pressure on Right Ventricular Hemodynamics and Ejection Fraction.
Biondi JW, Schulman DS, Soufer R, Matthay RA, Hines RL, Kay HR, Barash PG. The Effect of Incremental Positive End-Expiratory Pressure on Right Ventricular Hemodynamics and Ejection Fraction. Anesthesia & Analgesia 1988, 67: 144. PMID: 3277479, DOI: 10.1213/00000539-198802000-00007.Peer-Reviewed Original ResearchConceptsH2O positive end-expiratory pressurePositive end-expiratory pressureRight ventricular end-diastolic volume indexRight ventricular end-systolic volume indexEnd-systolic volume indexRight ventricular ejection fractionEnd-expiratory pressureVentricular end-diastolic volume indexVentricular end-systolic volume indexIncremental positive end-expiratory pressureEnd-diastolic volume indexVentricular ejection fractionEjection fractionVolume indexRV end-systolic volume indexSystolic pressure-volume relationRight ventricular hemodynamicsRight ventricular functionRight ventricular contractilityRV contractilityRV hemodynamicsSystolic pressureVentricular functionVentricular contractilityPressure-volume relationEffect of positive end-expiratory pressure on right ventricular performance Importance of baseline right ventricular function
Schulman D, Biondi J, Matthay R, Barash P, Zaret B, Soufer R. Effect of positive end-expiratory pressure on right ventricular performance Importance of baseline right ventricular function. The American Journal Of Medicine 1988, 84: 57-67. PMID: 3276186, DOI: 10.1016/0002-9343(88)90009-5.Peer-Reviewed Original ResearchConceptsRight ventricular ejection fractionBaseline right ventricular ejection fractionVentricular ejection fractionBaseline right ventricular functionRight ventricular functionEjection fractionContractile functionVentricular functionVentricular volumePositive end-expiratory pressure (PEEP) applicationSystolic pressure-volume relationPositive end-expiratory pressureRight ventricular contractile functionSystolic volume relationRight heart pressuresEffects of PEEPVentricular contractile functionEnd-expiratory pressureEnd-systolic volumeRight ventricular volumeH2O PEEPHeart pressuresPEEP levelsPressure-volume relationCardiac output