1998
Development and Reliability of a Method for Using Magnetic Resonance Imaging for the Definition of Regions of Interest for Positron Emission Tomography
Bremner JD, Bronen RA, De Erasquin G, Vermetten E, Staib LH, Ng CK, Soufer R, Charney DS, Innis RB. Development and Reliability of a Method for Using Magnetic Resonance Imaging for the Definition of Regions of Interest for Positron Emission Tomography. Molecular Imaging And Biology 1998, 1: 145-159. PMID: 14516589, DOI: 10.1016/s1095-0397(98)00015-6.Peer-Reviewed Original ResearchMagnetic resonance imagingPositron emission tomographyCoregistered magnetic resonance imagingResonance imagingBrain regionsEmission tomographyPoor anatomical resolutionAnatomical resolutionRegional metabolic rateBrain metabolic rateIntra-class correlation coefficientSuperior anatomical resolutionPET scansMRI scansMetabolic rateBrain scansPhysiologic informationAnatomical landmarksPET brain imagesReliable methodPets siteIndependent ratersScansImportant physiological informationStandard anatomical atlas
1997
Radiosynthesis and PET imaging of [N-methyl-11C]LY257327 as a tracer for 5-HT transporters
Zea-Ponce Y, Baldwin R, Stratton M, Al-Tikriti M, Soufer R, Schaus J, Innis R. Radiosynthesis and PET imaging of [N-methyl-11C]LY257327 as a tracer for 5-HT transporters. Nuclear Medicine And Biology 1997, 24: 251-254. PMID: 9228659, DOI: 10.1016/s0969-8051(97)00062-0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCarrier ProteinsChromatography, High Pressure LiquidCitalopramFemaleIsotope LabelingMaleMembrane GlycoproteinsMembrane Transport ProteinsNerve Tissue ProteinsOvariectomyPapioParoxetinePiperazinesRadiopharmaceuticalsRatsRats, Sprague-DawleySelective Serotonin Reuptake InhibitorsSerotonin Plasma Membrane Transport ProteinsSpectrophotometry, UltravioletTetrahydronaphthalenesTomography, Emission-ComputedConceptsSelective serotonin reuptake inhibitor citalopramSerotonin reuptake inhibitor citalopramReuptake inhibitor citalopramHigh brain uptakeSame brain regionsPositron emission tomographySerotonergic areasBrain uptakeMin postinjectionNontarget ratioUseful agentBrain regionsEmission tomographyN-methylMCi/mumolPET imagingNonspecific uptakeVivo studiesPartial inhibitionRadiochemical purityRadioactivity concentrationThalamusStriatumSerotoninCitalopram