2024
Obstructive Respiratory Disease in U.S. Veterans: Prevalence, Characteristics, and Health Burden
Bamonti P, Fischer I, Moye J, Poghosyan H, Pietrzak R. Obstructive Respiratory Disease in U.S. Veterans: Prevalence, Characteristics, and Health Burden. Journal Of Psychiatric Research 2024, 176: 140-147. PMID: 38857555, DOI: 10.1016/j.jpsychires.2024.05.053.Peer-Reviewed Original ResearchPhysical health burdenNationally representative sampleU.S. veteransObstructive respiratory diseaseHealth burdenRepresentative sampleNational Health and ResiliencePhysical health characteristicsRespiratory diseaseSecondary data analysisSevere somatic symptomsHealth characteristicsVA healthcareVeterans StudyTrauma burdenLow-incomeSomatic symptomsPosttraumatic stressMultivariate regression analysisVeteransMedical conditionsCurrent suicidal ideationGeneralized anxiety disorderMedical comorbiditiesNicotine use disorder
2023
Prevalence, characteristics, and health burden of rheumatoid arthritis in the U.S. veteran population
Morse J, Afari N, Norman S, Guma M, Pietrzak R. Prevalence, characteristics, and health burden of rheumatoid arthritis in the U.S. veteran population. Journal Of Psychiatric Research 2023, 159: 224-229. PMID: 36746059, DOI: 10.1016/j.jpsychires.2023.01.039.Peer-Reviewed Original ResearchConceptsAlcohol use disorderSubthreshold posttraumatic stress disorderPosttraumatic stress disorderRheumatoid arthritisMental health burdenHealth burdenU.S. veteransMedical conditionsSomatic symptomsLifetime alcohol use disorderMale U.S. veteransConditions/symptomsSevere somatic symptomsU.S. veteran populationU.S. military veteransMultivariable analysisTrauma burdenIndependent associationNational HealthRepresentative sampleCurrent insomniaPsychiatric characteristicsUse disordersVeteran populationGreater severity
2022
Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden
Nichter B, Koller D, De Angelis F, Wang J, Girgenti M, Na P, Hill M, Norman S, Krystal J, Gelernter J, Polimanti R, Pietrzak R. Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden. Psychological Medicine 2022, 53: 6325-6333. PMID: 36444557, DOI: 10.1017/s0033291722003646.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresUS military veteransLifetime suicide attemptsSuicide attemptsTrauma exposureTrauma burdenGenetic liabilityMilitary veteransDrug repurposing analysisPopulation-based sampleCumulative trauma exposureLifetime trauma exposureLow trauma exposureSuicide prediction modelsChronic inflammationInflammatory processNervous system developmentRisk scorePsychiatric characteristicsSuicidal behaviorExposure interactionsLarge genome-wide association studiesHigh levelsVeteransSuicidalityPrevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling in a National Sample of U.S. Military Veterans
Stefanovics E, Potenza M, Tsai J, Pietrzak R. Prevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling in a National Sample of U.S. Military Veterans. Journal Of Gambling Studies 2022, 39: 1077-1097. PMID: 36378356, DOI: 10.1007/s10899-022-10165-z.Peer-Reviewed Original ResearchConceptsCurrent psychiatric diagnosisU.S. military veteransUse disordersPsychiatric diagnosisMilitary veteransU.S. veteransDrug use disordersMental health treatmentSubstance use disordersChi-square testClinical characteristicsTrauma burdenNational HealthAdjusted associationsRoutine screeningClinical measuresRecreational gamblingCurrent prevalenceMale veteransHealth treatmentHigher household incomeSuicidal ideationVeterans StudyLogistic regressionExtensive involvement
2017
Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Mota NP, Han S, Harpaz‐Rotem I, Maruff P, Krystal JH, Southwick SM, Gelernter J, Pietrzak RH. Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Depression And Anxiety 2017, 35: 168-177. PMID: 29172227, PMCID: PMC5794529, DOI: 10.1002/da.22698.Peer-Reviewed Original ResearchConceptsΕ4 allele carriersApolipoprotein E gene polymorphismE gene polymorphismTrauma burdenU.S. military veteransAllele carriersPosttraumatic stress disorderPTSD symptomsNational HealthGreater social supportGene polymorphismsGreater severityMilitary veteransVeterans StudyAPOE ε4 carrier statusSocial supportΕ4 carrier statusAPOE genotypeΕ4 noncarriersPosttraumatic stress symptomsIndependent replication sampleSymptomsPTSD riskStress disorderCarrier status