Chemical entity normalization for successful translational development of Alzheimer’s disease and dementia therapeutics
Mullin S, McDougal R, Cheung K, Kilicoglu H, Beck A, Zeiss C. Chemical entity normalization for successful translational development of Alzheimer’s disease and dementia therapeutics. Journal Of Biomedical Semantics 2024, 15: 13. PMID: 39080729, PMCID: PMC11290083, DOI: 10.1186/s13326-024-00314-1.Peer-Reviewed Original ResearchConceptsEntity normalizationChemical mentionsNatural language modelDictionary-based methodsDictionary-based approachCRAFT corpusDownstream tasksLanguage modelChemical Entities of Biological InterestPubMedBERT modelDisambiguationChEBIDownstream applicationsArticle abstractsRelationship typesMentionsPubMedBERTOntologyDementia literatureTaskDementia CohortMethodEntitiesAccuracyDementiaGPT-4 Performance for Neurologic Localization
Lee J, Choi E, McDougal R, Lytton W. GPT-4 Performance for Neurologic Localization. Neurology Clinical Practice 2024, 14: e200293. PMID: 38596779, PMCID: PMC11003355, DOI: 10.1212/cpj.0000000000200293.Peer-Reviewed Original ResearchGenerative Pretrained TransformerText classificationText datasetsClass labelsPretrained TransformerLanguage modelF1 scorePerformance metricsKnowledge baseMetricsInadequate knowledge baseClassificationReduce health care disparitiesClinical reasoningCapabilityPerformanceTextHealth care disparitiesDatasetSoftware