1986
Changes in the phenotype of human small cell lung cancer cell lines after transfection and expression of the c-myc proto-oncogene.
Johnson B, Battey J, Linnoila I, Becker K, Makuch R, Snider R, Carney D, Minna J. Changes in the phenotype of human small cell lung cancer cell lines after transfection and expression of the c-myc proto-oncogene. Journal Of Clinical Investigation 1986, 78: 525-532. PMID: 3016030, PMCID: PMC423589, DOI: 10.1172/jci112604.Peer-Reviewed Original ResearchConceptsSmall cell lung cancer cell linesCell lung cancer cell linesLung cancer cell linesCancer cell linesBombesin-like immunoreactivityLarge cell morphologyC-myc messenger RNAC-myc expressionC-MycCell linesSmall cell lung cancerHuman small cell lung cancer cell linesCell lung cancerSmall cell lung cancer linesCell lung cancer linesMessenger RNALung cancer linesC-myc amplificationC-myc geneLung cancerVariant phenotypesCloning efficiencyDecarboxylase levelsCancer linesBiologic properties
1982
Flow cytometric analysis of DNA content of bone marrow cells in patients with plasma cell myeloma: clinical implications.
Bunn P, Krasnow S, Makuch R, Schlam M, Schechter G. Flow cytometric analysis of DNA content of bone marrow cells in patients with plasma cell myeloma: clinical implications. Blood 1982, 59: 528-35. PMID: 6800416, DOI: 10.1182/blood.v59.3.528.bloodjournal593528.Peer-Reviewed Original ResearchConceptsTumor DNA contentMyeloma patientsPlasma cell myelomaAneuploid tumor cellsPlasma cellsWaldenstrom's macroglobulinemiaCell myelomaTumor cellsTime of diagnosisTime of relapseIndependent prognostic significanceCourse of illnessClinical drug resistancePotential clinical usefulnessBone marrow cellsDNA contentClinical relapseRenal failureSerum creatininePrognostic significanceDiploid tumorsAneuploid tumorsDevelopment of aneuploidyClinical significanceClinical usefulness