1999
Use of Meta-Analysis to Evaluate Medical Questions of Interest: An Application to Studies of Secondary Prevention of Acute Myocardial Infarction
Chen Y, Makuch R. Use of Meta-Analysis to Evaluate Medical Questions of Interest: An Application to Studies of Secondary Prevention of Acute Myocardial Infarction. Therapeutic Innovation & Regulatory Science 1999, 33: 1161-1171. DOI: 10.1177/009286159903300420.Peer-Reviewed Original ResearchAcute myocardial infarctionMyocardial infarctionImportant public health implicationsCombinability of studiesNonfatal myocardial infarctionPublic health implicationsLiterature search strategySecondary preventionMeta-AnalysisMethodologic issuesInfarctionStudy homogeneityHealth implicationsIndividual studiesProtocol developmentMedical questionsSearch strategyPatientsMedical research
1989
Issues in planning and interpreting active control equivalence studies
Makuch R, Johnson M. Issues in planning and interpreting active control equivalence studies. Journal Of Clinical Epidemiology 1989, 42: 503-511. PMID: 2661729, DOI: 10.1016/0895-4356(89)90146-7.Peer-Reviewed Original ResearchConceptsActive control equivalence studiesEquivalence studyActive-control equivalence trialsPrevention of strokeNew drugsActive control drugActive control treatmentAlternative study designsCurrent therapiesPlaceboControl drugTherapeutic equivalenceEquivalence trialNew treatmentsMethodologic issuesDrug efficacyStudy designTreatment controlDrugsEfficacyEquivalence designTrialsTreatmentStudy validation