2000
Pharmacologic Treatment of Tic Disorders
Scahill L, Chappell P, King R, Leckman J. Pharmacologic Treatment of Tic Disorders. Child And Adolescent Psychiatric Clinics Of North America 2000, 9: 99-117. PMID: 10674192, DOI: 10.1016/s1056-4993(18)30137-8.Peer-Reviewed Original ResearchConceptsTic disordersTreatment of ADHDAtypical neurolepticsLong-term side effectsNewer atypical neurolepticsFirst-line treatmentTreatment of ticsBotulinum toxin injectionMore studiesUse of stimulantsNonstimulant medicationsToxin injectionPharmacologic treatmentPsychiatric comorbidityStandard treatmentTraditional neurolepticsTarget symptomsSide effectsStimulant medicationMedicationsNeurolepticsAdverse effectsComorbid ADHDDisordersTreatment planning
1995
Risperidone Treatment of Children and Adolescents with Chronic Tic Disorders: A Preliminary Report
LOMBROSO P, SCAHILL L, KING R, LYNCH K, CHAPPELL P, PETERSON B, McDOUGLE C, LECKMAN J. Risperidone Treatment of Children and Adolescents with Chronic Tic Disorders: A Preliminary Report. Journal Of The American Academy Of Child & Adolescent Psychiatry 1995, 34: 1147-1152. PMID: 7559308, DOI: 10.1097/00004583-199509000-00011.Peer-Reviewed Original ResearchConceptsChronic tic disorderTic disordersObsessive-compulsive disorderChronic motor tic disorderYale Global Tic Severity ScaleDopamine-blocking propertiesOpen-label trialFrequent side effectsEfficacy of risperidoneMotor tic disorderShort-term safetyTic Severity ScaleComorbid obsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleObsessive Compulsive ScaleClinical responseRisperidone treatmentMean ageTic scoreSeverity ScaleSide effectsTourette syndromeComorbid diagnosesTic frequencyWeight gain