2021
Justice and equity in pragmatic clinical trials: Considerations for pain research within integrated health systems
Ali J, Davis AF, Burgess DJ, Rhon DI, Vining R, Young‐McCaughan S, Green S, Kerns RD. Justice and equity in pragmatic clinical trials: Considerations for pain research within integrated health systems. Learning Health Systems 2021, 6: e10291. PMID: 35434355, PMCID: PMC9006531, DOI: 10.1002/lrh2.10291.Peer-Reviewed Original ResearchPragmatic clinical trialsPain management researchIntegrated health systemCo-occurring conditionsHealth systemClinical trialsEvidence-based therapiesClinical Trials NetworkVeterans Health SystemMultidisciplinary working groupPain researchEquitable careStudy settingTrials NetworkHealth inequitiesHealth equityEquitable healthcareHealthcare deliveryPainTrialsWorking GroupRelevant literaturePatientsGroupTherapyIncorporating walking into cognitive behavioral therapy for chronic pain: safety and effectiveness of a personalized walking intervention
Heapy AA, Tankha H, Higgins DM, Driscoll M, LaChappelle KM, Goulet JL, Buta E, Piette JD, Kerns RD, Krein SL. Incorporating walking into cognitive behavioral therapy for chronic pain: safety and effectiveness of a personalized walking intervention. Journal Of Behavioral Medicine 2021, 44: 260-269. PMID: 33386530, DOI: 10.1007/s10865-020-00193-8.Peer-Reviewed Original ResearchConceptsAdverse eventsCognitive behavioral therapyChronic painBehavioral therapyCBT-CPLongstanding painWalking interventionsDaily stepsTreatment groupsPainInteractive voice responseStudy sampleWeekly goalsSignificant differencesSignificant increaseTherapyTreatmentParticipantsVoice responseSafetyPersonsBaselineWeeks
2020
Cognitive Behavioral Therapy for the Management of Multiple Sclerosis–Related Pain
Gromisch ES, Kerns RD, Czlapinski R, Beenken B, Otis J, Lo AC, Beauvais J. Cognitive Behavioral Therapy for the Management of Multiple Sclerosis–Related Pain. International Journal Of MS Care 2020, 22: 8-14. PMID: 32123523, PMCID: PMC7041614, DOI: 10.7224/1537-2073.2018-023.Peer-Reviewed Original ResearchCognitive behavioral therapyMultiple sclerosisDepressive symptom severityPain severityBehavioral therapyStandard carePain interferenceSymptom severityModerate pain severityHelpful adjunctive treatmentAdjunctive treatmentPrimary outcomeTreatment satisfactionEffective treatmentTreatment groupsPainEducation-based programsDaily functioningTherapySeverityBehavioral goalsSclerosisSignificant differencesTreatmentCare
2019
Graded chronic pain scale revised: mild, bothersome, and high-impact chronic pain.
Von Korff M, DeBar LL, Krebs EE, Kerns RD, Deyo RA, Keefe FJ. Graded chronic pain scale revised: mild, bothersome, and high-impact chronic pain. Pain 2019, 161: 651-661. PMID: 31764390, PMCID: PMC7097879, DOI: 10.1097/j.pain.0000000000001758.Peer-Reviewed Original ResearchConceptsHigh-impact chronic painMild chronic painChronic Pain ScaleGraded Chronic Pain ScaleChronic painPain Scale-RevisedPain scaleLong-term opioid therapySubstantial activity limitationsHealth status indicatorsOpioid therapyAdult enrolleesActivity limitationsPainPain metricsHealth plansNonsignificant differenceStatus indicatorsPersonsValid methodTherapyPrevalenceBothersomeEnrolleesSignature Informed Consent for Long-Term Opioid Therapy in Patients With Cancer: Perspectives of Patients and Providers
Giannitrapani KF, Fereydooni S, Azarfar A, Silveira MJ, Glassman PA, Midboe AM, Bohnert ABS, Zenoni MA, Kerns RD, Pearlman RA, Asch SM, Becker W, Lorenz KA. Signature Informed Consent for Long-Term Opioid Therapy in Patients With Cancer: Perspectives of Patients and Providers. Journal Of Pain And Symptom Management 2019, 59: 49-57. PMID: 31476361, DOI: 10.1016/j.jpainsymman.2019.08.020.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyCancer-related painOpioid therapyVeterans Health Administration medical centersInformed consentAppropriate literacy levelPerspectives of patientsPatient-provider relationshipCancer-related concernsOpioid useOpioid prescribersPatient interviewsPatient educationMedical CenterPatientsPainProvider perspectivesTherapyCancerConsentLiteracy levelsProvidersPotential disadvantagesEmergent themesOpioids
2018
Racial disparities in discontinuation of long-term opioid therapy following illicit drug use among black and white patients
Gaither JR, Gordon K, Crystal S, Edelman EJ, Kerns RD, Justice AC, Fiellin DA, Becker WC. Racial disparities in discontinuation of long-term opioid therapy following illicit drug use among black and white patients. Drug And Alcohol Dependence 2018, 192: 371-376. PMID: 30122319, PMCID: PMC7106601, DOI: 10.1016/j.drugalcdep.2018.05.033.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyIllicit drug useUrine drug testsDrug useOpioid therapyWhite racePositive urine drug testDrug testsMonths of treatmentElectronic medical recordsWhite patientsChronic painPatient raceMedical recordsPatientsLogistic regressionOpioidsRacial disparitiesDrug testingCocaineCannabisTherapyCliniciansDiscontinuationPainCognitive Behavioral Therapy for Veterans With Tinnitus.
Schmidt CJ, Kerns RD, Finkel S, Michaelides E, Henry JA. Cognitive Behavioral Therapy for Veterans With Tinnitus. Federal Practitioner 2018, 35: 36-46. PMID: 30766380, PMCID: PMC6263445.Peer-Reviewed Original Research
2017
Developing a typology of patient-generated behavioral goals for cognitive behavioral therapy for chronic pain (CBT-CP): classification and predicting outcomes
Heapy AA, Wandner L, Driscoll MA, LaChappelle K, Czlapinski R, Fenton BT, Piette JD, Aikens JE, Janevic MR, Kerns RD. Developing a typology of patient-generated behavioral goals for cognitive behavioral therapy for chronic pain (CBT-CP): classification and predicting outcomes. Journal Of Behavioral Medicine 2017, 41: 174-185. PMID: 28936717, DOI: 10.1007/s10865-017-9885-4.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyChronic painYard workTreatment outcomesPhysical activityDepressive symptomsPain-related interferenceWork/schoolPain intensityFunctional statusTreatment goalsPredicting OutcomePatient valuesMeaningful improvementsOutcome domainsBehavioral therapyWellness goalsRecreational activitiesPainTherapyOutcomesSymptomsBehavioral goalsActivityMultiple Sources of Prescription Payment and Risky Opioid Therapy Among Veterans
Becker WC, Fenton BT, Brandt CA, Doyle EL, Francis J, Goulet JL, Moore BA, Torrise V, Kerns RD, Kreiner PW. Multiple Sources of Prescription Payment and Risky Opioid Therapy Among Veterans. Medical Care 2017, 55: s33-s36. PMID: 28410338, DOI: 10.1097/mlr.0000000000000722.Peer-Reviewed Original ResearchConceptsOpioid therapySource of paymentHigher oddsHigh-dose opioid therapyHigh-risk opioid prescribingMorphine equivalent daily dosePayment sourceOpioid analgesic prescriptionsPrescription monitoring programsEquivalent daily doseCross-sectional studyAnalgesic prescriptionOpioid prescribingBenzodiazepine therapyDaily doseUS veteransFiscal year 2014TherapyPrivate insuranceLogistic regressionRelated harmsPrescription paymentAnalytic sampleOpioidsOdds
2016
Drug Counselors’ Attitudes Toward Nonpharmacologic Treatments for Chronic Pain
Oberleitner LM, Beitel M, Schottenfeld RS, Kerns RD, Doucette C, Napoleone R, Liong C, Barry DT. Drug Counselors’ Attitudes Toward Nonpharmacologic Treatments for Chronic Pain. Journal Of Addiction Medicine 2016, 10: 34-39. PMID: 26690289, PMCID: PMC4733570, DOI: 10.1097/adm.0000000000000177.Peer-Reviewed Original ResearchConceptsChronic painNonpharmacologic treatmentsDrug counselorsNonpharmacologic pain treatmentsMethadone-maintained patientsInterdisciplinary pain managementMethadone maintenance treatmentVulnerable patient populationCognitive behavioral therapyNonpharmacologic interventionsPain managementPain treatmentPain interventionsMaintenance treatmentPatient populationPainPatientsHerbal medicineGroup interventionEfficacyInterventionTreatmentPerceived EfficacyTherapyUndertreatmentInitial development of patient-reported instrument assessing harm, efficacy, and misuse of long-term opioid therapy
Becker WC, Fiellin DA, Black AC, Kostovich CT, Kerns RD, Fraenkel L. Initial development of patient-reported instrument assessing harm, efficacy, and misuse of long-term opioid therapy. The Journal Of Rehabilitation Research And Development 2016, 53: 127-136. PMID: 27006339, PMCID: PMC4806533, DOI: 10.1682/jrrd.2014.11.0285.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyPatient-reported instrumentOpioid therapyFurther item reductionIneffective medicationsClinical outcomesPrimary careFrequent reassessmentPatient comprehensionItem reductionGold standardEfficacyTherapyInterdisciplinary teamLevel checksCognitive interviewsMisuseHarmMedicationsPatientsStepped care model of pain management and quality of pain care in long-term opioid therapy
Moore BA, Anderson D, Dorflinger L, Zlateva I, Lee A, Gilliam W, Tian T, Khatri K, Ruser CB, Kerns RD. Stepped care model of pain management and quality of pain care in long-term opioid therapy. The Journal Of Rehabilitation Research And Development 2016, 53: 137-146. PMID: 27006068, DOI: 10.1682/jrrd.2014.10.0254.Peer-Reviewed Original Research
2015
Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV
Becker WC, Gordon K, Jennifer Edelman E, Kerns RD, Crystal S, Dziura JD, Fiellin LE, Gordon AJ, Goulet JL, Justice AC, Fiellin DA. Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV. AIDS And Behavior 2015, 20: 679-686. PMID: 26384973, PMCID: PMC5006945, DOI: 10.1007/s10461-015-1197-5.Peer-Reviewed Original Research
2013
A Research Agenda for Enhancing Appropriate Opioid Prescribing in Primary Care
Becker WC, Fraenkel L, Kerns RD, Fiellin DA. A Research Agenda for Enhancing Appropriate Opioid Prescribing in Primary Care. Journal Of General Internal Medicine 2013, 28: 1364-1367. PMID: 23568187, PMCID: PMC3785661, DOI: 10.1007/s11606-013-2422-4.Peer-Reviewed Educational MaterialsConceptsOpioid prescribingLong-term opioid therapyMulti-modal treatment planAppropriate opioid prescribingOpioid analgesic therapyPatient-reported safetyEvidence-based algorithmOpioid therapyOptimize therapyAnalgesic therapyChronic painPotent medicationsInadequate efficacyPrimary careQuality improvement workPatient sufferingMild toxicityTreatment planScant dataTherapyPrescribingEfficacyPatientsOutcomesToxicityInstruments to assess patient‐reported safety, efficacy, or misuse of current opioid therapy for chronic pain: A systematic review
Becker WC, Fraenkel L, Edelman J, Holt SR, Glover J, Kerns RD, Fiellin DA. Instruments to assess patient‐reported safety, efficacy, or misuse of current opioid therapy for chronic pain: A systematic review. Pain 2013, 154: 905-916. PMID: 23601625, PMCID: PMC3683236, DOI: 10.1016/j.pain.2013.02.031.Peer-Reviewed Original ResearchConceptsPatient-reported safetyOpioid therapyChronic painInclusion criteriaSystematic reviewOngoing opioid therapyPsychometric testsLack of testingEligible studiesClinical practiceInitial searchStatistical significanceDiagnostic accuracy testingPainEfficacyTherapyEfficacy itemsContent expertsSafetyLimited assessmentReviewLiterature reviewGeneralizability limitationsFurther researchIndividual items
2011
Measurement of adherence to clinical practice guidelines for opioid therapy for chronic pain
Midboe AM, Lewis ET, Paik MC, Gallagher RM, Rosenberg JM, Goodman F, Kerns RD, Becker WC, Trafton JA. Measurement of adherence to clinical practice guidelines for opioid therapy for chronic pain. Translational Behavioral Medicine 2011, 2: 57-64. PMID: 24073098, PMCID: PMC3717811, DOI: 10.1007/s13142-011-0104-5.Peer-Reviewed Original ResearchClinical practice guidelinesOpioid therapyChronic painPractice guidelinesDefense Clinical Practice GuidelineVeterans Affairs/DepartmentChronic opioid therapyPatient-oriented interventionsMeasurement of adherenceHealth care prioritiesSystem-level factorsQuality improvement approachEffective prescribingCare prioritiesTherapyPainAdherenceLevel factorsDepartmentGuidelinesPrescribingProblematic use
2005
Multidisciplinary approaches to pain management in primary care settings.
Otis J, Reid M, Kerns R. Multidisciplinary approaches to pain management in primary care settings. 2005, 41-59. DOI: 10.1037/10962-003.ChaptersPrimary care settingClinical health psychologistsCare settingsPain managementMultidisciplinary chronic pain managementHealth psychologistsPain management centerChronic pain managementStepped care modelClinical research groupChronic painImproved outcomesCare modelBehavioral therapyPainPrimary aimTraining programSpecific roleSettingPatientsTherapy
2001
Cognitive-behavioral therapy for chronic pain in the elderly
Kerns R, Otis J, Marcus K. Cognitive-behavioral therapy for chronic pain in the elderly. Clinics In Geriatric Medicine 2001, 17: 503-523. PMID: 11459718, DOI: 10.1016/s0749-0690(05)70083-5.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyChronic painChronic nonmalignant painNonpharmacologic treatment optionsAmbulatory care settingsDetails of assessmentNonmalignant painPain managementTreatment optionsCare settingsElderly gentlemanPainTherapyTreatment conceptualizationRelevant developmental issuesCognitive-behavioral perspectiveDevelopmental issues