2017
Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern?
Simmons MA, Elder RW, Shabanova V, Hellenbrand W, Asnes J. Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern? Catheterization And Cardiovascular Interventions 2017, 91: 920-926. PMID: 29280541, DOI: 10.1002/ccd.27454.Peer-Reviewed Original ResearchConceptsTranscatheter pulmonary valve implantationRight ventricular outflow tractNative outflow tractsSignificant ventricular arrhythmiasPulmonary valve implantationVentricular arrhythmiasOutflow tractValve implantationAnti-arrhythmic medicationsBeta-blocker therapySingle-center studyVentricular outflow tractLong-term therapySudden cardiac deathCare of patientsChange of doseHemodynamic instabilityHemodynamic compromiseCardiac deathMedian ageMedical therapyPediatric patientsSignificant arrhythmiasCenter studyTerm therapy
2016
“Frontiers in Fontan failure: A summary of conference proceedings”
Hebson C, Book W, Elder RW, Ford R, Jokhadar M, Kanter K, Kogon B, Kovacs AH, Levit RD, Lloyd M, Maher K, Reshamwala P, Rodriguez F, Romero R, Tejada T, Valente A, Veldtman G, McConnell M. “Frontiers in Fontan failure: A summary of conference proceedings”. Congenital Heart Disease 2016, 12: 6-16. PMID: 27597140, DOI: 10.1111/chd.12407.Peer-Reviewed Original ResearchCatheter‐measured Hemodynamics of Adult Fontan Circulation: Associations with Adverse Event and End‐organ Dysfunctions
Mori M, Hebson C, Shioda K, Elder RW, Kogon BE, Rodriguez FH, Jokhadar M, Book WM. Catheter‐measured Hemodynamics of Adult Fontan Circulation: Associations with Adverse Event and End‐organ Dysfunctions. Congenital Heart Disease 2016, 11: 589-597. PMID: 26932151, DOI: 10.1111/chd.12345.Peer-Reviewed Original ResearchMeSH KeywordsAdultCardiac CatheterizationChi-Square DistributionFemaleFontan ProcedureGeorgiaHeart Defects, CongenitalHeart FailureHeart TransplantationHemodynamicsHumansKidney DiseasesLinear ModelsLiver DiseasesMaleMultivariate AnalysisPredictive Value of TestsProportional Hazards ModelsRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeYoung AdultConceptsPulmonary capillary wedge pressureHigh central venous pressureCentral venous pressureEnd-organ dysfunctionSystemic vascular resistance indexCox proportional hazards analysisAdult Fontan patientsProportional hazards analysisCardiac indexFontan patientsAdverse eventsFontan circulationHemodynamic measurementsHigh systemic vascular resistance indexMultivariate Cox proportional hazards analysisRight heart catheterization dataSignificant associationLow cardiac indexVascular resistance indexCapillary wedge pressureChild-Pugh scoreSerious adverse eventsVenous outflow obstructionHigher cardiac indexPost-Fontan patients
2015
Modern Incidence of Complete Heart Block in Patients with L‐looped Ventricles: Does Univentricular Status Matter?
Simmons MA, Rollinson N, Fishberger S, Qin L, Fahey J, Elder RW. Modern Incidence of Complete Heart Block in Patients with L‐looped Ventricles: Does Univentricular Status Matter? Congenital Heart Disease 2015, 10: e237-e242. PMID: 26077963, DOI: 10.1111/chd.12279.Peer-Reviewed Original ResearchConceptsComplete heart blockSpontaneous complete heart blockSingle ventricle anatomyHeart blockL-transpositionGreat arteriesVentricle anatomyYale-New Haven HospitalGroup III patientsTwo-ventricle anatomyRetrospective cohort studyMajor cardiac defectsAge of onsetSized ventriclesVentricle patientsCohort studyMedian ageModern cohortPerson yearsIII patientsIncidence rateSimilar riskPatientsArteryCardiac defects
2014
Risk Factors for Major Adverse Events Late after Fontan Palliation
Elder RW, McCabe NM, Veledar E, Kogon BE, Jokhadar M, Rodriguez FH, McConnell ME, Book WM. Risk Factors for Major Adverse Events Late after Fontan Palliation. Congenital Heart Disease 2014, 10: 159-168. PMID: 25130602, PMCID: PMC4512755, DOI: 10.1111/chd.12212.Peer-Reviewed Original ResearchConceptsMajor adverse eventsAdult Fontan patientsAdverse eventsRisk factorsFontan patientsFontan palliationOxygen desaturationPortal hypertensionVentricular functionAdverse outcomesTransplant-free survival rateLate-term outcomesSystemic oxygen desaturationSystolic ventricular functionAdverse event profileCongestive heart failureKaplan-Meier methodTertiary academic centerAdditional risk factorsImportant risk factorMode of deathFontan failureFontan typeSystemic ventricleThromboembolic events