2016
Catheter‐measured Hemodynamics of Adult Fontan Circulation: Associations with Adverse Event and End‐organ Dysfunctions
Mori M, Hebson C, Shioda K, Elder RW, Kogon BE, Rodriguez FH, Jokhadar M, Book WM. Catheter‐measured Hemodynamics of Adult Fontan Circulation: Associations with Adverse Event and End‐organ Dysfunctions. Congenital Heart Disease 2016, 11: 589-597. PMID: 26932151, DOI: 10.1111/chd.12345.Peer-Reviewed Original ResearchMeSH KeywordsAdultCardiac CatheterizationChi-Square DistributionFemaleFontan ProcedureGeorgiaHeart Defects, CongenitalHeart FailureHeart TransplantationHemodynamicsHumansKidney DiseasesLinear ModelsLiver DiseasesMaleMultivariate AnalysisPredictive Value of TestsProportional Hazards ModelsRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeYoung AdultConceptsPulmonary capillary wedge pressureHigh central venous pressureCentral venous pressureEnd-organ dysfunctionSystemic vascular resistance indexCox proportional hazards analysisAdult Fontan patientsProportional hazards analysisCardiac indexFontan patientsAdverse eventsFontan circulationHemodynamic measurementsHigh systemic vascular resistance indexMultivariate Cox proportional hazards analysisRight heart catheterization dataSignificant associationLow cardiac indexVascular resistance indexCapillary wedge pressureChild-Pugh scoreSerious adverse eventsVenous outflow obstructionHigher cardiac indexPost-Fontan patients
2013
Hemodynamic Phenotype of the Failing Fontan in an Adult Population
Hebson CL, McCabe NM, Elder RW, Mahle WT, McConnell M, Kogon BE, Veledar E, Jokhadar M, Vincent RN, Sahu A, Book WM. Hemodynamic Phenotype of the Failing Fontan in an Adult Population. The American Journal Of Cardiology 2013, 112: 1943-1947. PMID: 24075283, PMCID: PMC4505550, DOI: 10.1016/j.amjcard.2013.08.023.Peer-Reviewed Original ResearchConceptsFontan failureCardiac indexFontan patientsLiver diseaseSVR indexLower systemic vascular resistance indexNormal systolic ventricular functionSystemic vascular resistance indexAdult Fontan patientsSimilar cardiac indexSystolic ventricular functionVascular resistance indexSignificant liver diseasePediatric Fontan patientsCase-cohort analysisFailing FontanPF cohortsPortal hypertensionAdult patientsCatheterization findingsFontan circulationHeart failureVentricular functionCirculatory derangementsPediatric cohort