2017
Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern?
Simmons MA, Elder RW, Shabanova V, Hellenbrand W, Asnes J. Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern? Catheterization And Cardiovascular Interventions 2017, 91: 920-926. PMID: 29280541, DOI: 10.1002/ccd.27454.Peer-Reviewed Original ResearchConceptsTranscatheter pulmonary valve implantationRight ventricular outflow tractNative outflow tractsSignificant ventricular arrhythmiasPulmonary valve implantationVentricular arrhythmiasOutflow tractValve implantationAnti-arrhythmic medicationsBeta-blocker therapySingle-center studyVentricular outflow tractLong-term therapySudden cardiac deathCare of patientsChange of doseHemodynamic instabilityHemodynamic compromiseCardiac deathMedian ageMedical therapyPediatric patientsSignificant arrhythmiasCenter studyTerm therapy
2015
Modern Incidence of Complete Heart Block in Patients with L‐looped Ventricles: Does Univentricular Status Matter?
Simmons MA, Rollinson N, Fishberger S, Qin L, Fahey J, Elder RW. Modern Incidence of Complete Heart Block in Patients with L‐looped Ventricles: Does Univentricular Status Matter? Congenital Heart Disease 2015, 10: e237-e242. PMID: 26077963, DOI: 10.1111/chd.12279.Peer-Reviewed Original ResearchConceptsComplete heart blockSpontaneous complete heart blockSingle ventricle anatomyHeart blockL-transpositionGreat arteriesVentricle anatomyYale-New Haven HospitalGroup III patientsTwo-ventricle anatomyRetrospective cohort studyMajor cardiac defectsAge of onsetSized ventriclesVentricle patientsCohort studyMedian ageModern cohortPerson yearsIII patientsIncidence rateSimilar riskPatientsArteryCardiac defectsImmunologic Aging in Adults with Congenital Heart Disease: Does Infant Sternotomy Matter?
Elder RW, George RP, McCabe NM, Rodriguez III FH, Book WM, Mahle WT, Kirk AD. Immunologic Aging in Adults with Congenital Heart Disease: Does Infant Sternotomy Matter? Pediatric Cardiology 2015, 36: 1411-1416. PMID: 25916315, PMCID: PMC5319831, DOI: 10.1007/s00246-015-1174-9.Peer-Reviewed Original ResearchConceptsAdult congenital heart diseaseCongenital heart diseaseACHD patientsHeart diseaseExact testMean percentageImmune phenotypic changesT lymphocyte compositionCD8 T cellsFisher's exact testPolychromatic flow cytometryT cell maturationMann-Whitney ULower mean percentageImmune exhaustionImmunologic exhaustionPrior sternotomyCD8 lymphocytesCD4 cellsCD8 cellsLymphocyte compositionMedian ageClinical impactT cellsT lymphocytes
2012
Outcomes of the infant Ross procedure for congenital aortic stenosis followed into adolescence
Elder RW, Quaegebeur JM, Bacha EA, Chen JM, Bourlon F, Williams IA. Outcomes of the infant Ross procedure for congenital aortic stenosis followed into adolescence. Journal Of Thoracic And Cardiovascular Surgery 2012, 145: 1504-1511. PMID: 23062969, PMCID: PMC3657341, DOI: 10.1016/j.jtcvs.2012.09.004.Peer-Reviewed Original ResearchConceptsCongenital aortic stenosisRoss procedureLong-term outcomesAortic stenosisRight ventricular outflow tract reinterventionVentricular outflow tract reinterventionRight ventricular outflow tractSignificant aortic stenosisVentricular outflow tractAortic valve diseaseNew York-PresbyterianAvoidance of anticoagulationCatheter-based interventionsMonths of ageAutograft annulusAutograft growthAutograft reinterventionAortic insufficiencyLatest followMedian ageRetrospective reviewRoss operationCardiothoracic centreRecent followModerate dilatation