2019
Modern Day Care of Patients With Single Ventricle Heart Disease: Late Complications of Fontan Palliation
Simmons M, Elder R. Modern Day Care of Patients With Single Ventricle Heart Disease: Late Complications of Fontan Palliation. Current Pediatrics Reports 2019, 7: 53-61. DOI: 10.1007/s40124-019-00192-7.Peer-Reviewed Original ResearchFontan palliationSingle ventricle heart diseaseLate hepatic complicationsHepatic complicationsPulmonary vasodilatorsReviewThe majorityFontan failureVascular complicationsFontan operationLate complicationsHeart failureHeart diseaseLymphatic complicationsNovel therapiesLiver cancerHigh riskComplicationsRecent FindingsRecentScoring systemPatientsDay carePalliationTherapyStructural complicationsSeparate entities
2016
“Frontiers in Fontan failure: A summary of conference proceedings”
Hebson C, Book W, Elder RW, Ford R, Jokhadar M, Kanter K, Kogon B, Kovacs AH, Levit RD, Lloyd M, Maher K, Reshamwala P, Rodriguez F, Romero R, Tejada T, Valente A, Veldtman G, McConnell M. “Frontiers in Fontan failure: A summary of conference proceedings”. Congenital Heart Disease 2016, 12: 6-16. PMID: 27597140, DOI: 10.1111/chd.12407.Peer-Reviewed Original ResearchClinical Approaches to the Patient with a Failing Fontan Procedure
Elder RW, Wu FM. Clinical Approaches to the Patient with a Failing Fontan Procedure. Current Cardiology Reports 2016, 18: 44. PMID: 27002620, DOI: 10.1007/s11886-016-0716-y.Peer-Reviewed Original ResearchConceptsClinical approachPotential therapeutic optionGeneral clinical approachLong-term healthFontan failureFontan populationFontan operationFontan procedureFontan survivorsFontan circulationUniventricular heartPatient presentingTherapeutic optionsOrgan systemsAltered physiologyVaried manifestationsVulnerable populationsMulti-institutional collaborationPatientsModern managementVast majorityExtracardiacPresentingPopulationCardiologists
2014
Risk Factors for Major Adverse Events Late after Fontan Palliation
Elder RW, McCabe NM, Veledar E, Kogon BE, Jokhadar M, Rodriguez FH, McConnell ME, Book WM. Risk Factors for Major Adverse Events Late after Fontan Palliation. Congenital Heart Disease 2014, 10: 159-168. PMID: 25130602, PMCID: PMC4512755, DOI: 10.1111/chd.12212.Peer-Reviewed Original ResearchConceptsMajor adverse eventsAdult Fontan patientsAdverse eventsRisk factorsFontan patientsFontan palliationOxygen desaturationPortal hypertensionVentricular functionAdverse outcomesTransplant-free survival rateLate-term outcomesSystemic oxygen desaturationSystolic ventricular functionAdverse event profileCongestive heart failureKaplan-Meier methodTertiary academic centerAdditional risk factorsImportant risk factorMode of deathFontan failureFontan typeSystemic ventricleThromboembolic events
2013
Hemodynamic Phenotype of the Failing Fontan in an Adult Population
Hebson CL, McCabe NM, Elder RW, Mahle WT, McConnell M, Kogon BE, Veledar E, Jokhadar M, Vincent RN, Sahu A, Book WM. Hemodynamic Phenotype of the Failing Fontan in an Adult Population. The American Journal Of Cardiology 2013, 112: 1943-1947. PMID: 24075283, PMCID: PMC4505550, DOI: 10.1016/j.amjcard.2013.08.023.Peer-Reviewed Original ResearchConceptsFontan failureCardiac indexFontan patientsLiver diseaseSVR indexLower systemic vascular resistance indexNormal systolic ventricular functionSystemic vascular resistance indexAdult Fontan patientsSimilar cardiac indexSystolic ventricular functionVascular resistance indexSignificant liver diseasePediatric Fontan patientsCase-cohort analysisFailing FontanPF cohortsPortal hypertensionAdult patientsCatheterization findingsFontan circulationHeart failureVentricular functionCirculatory derangementsPediatric cohort