2014
Subclinical seizures during intracranial EEG recording: Are they clinically significant?
Farooque P, Duckrow R. Subclinical seizures during intracranial EEG recording: Are they clinically significant? Epilepsy Research 2014, 108: 1790-1796. PMID: 25306063, DOI: 10.1016/j.eplepsyres.2014.09.020.Peer-Reviewed Original ResearchConceptsPoor surgical outcomesGood surgical outcomeSubclinical seizuresSurgical outcomesClinical seizuresIntracranial EEG recordingsGroup 2Group 1Extra-temporal lobe epilepsySeizure onset regionEEG recordingsExtra-temporal originResection correlatesSurgical resectionLobe epilepsyPoor outcomePrognostic valueClinical significanceBetter outcomesPatientsSeizuresEpileptic networkOnset zoneDifferent anatomical regionsEpilepsy database
2013
7T MR spectroscopic imaging in the localization of surgical epilepsy
Pan JW, Duckrow RB, Gerrard J, Ong C, Hirsch LJ, Resor SR, Zhang Y, Petroff O, Spencer S, Hetherington HP, Spencer DD. 7T MR spectroscopic imaging in the localization of surgical epilepsy. Epilepsia 2013, 54: 1668-1678. PMID: 23895497, PMCID: PMC3938332, DOI: 10.1111/epi.12322.Peer-Reviewed Original ResearchConceptsSevere metabolic abnormalitiesLocalization-related epilepsyMR spectroscopic imagingN-acetyl aspartateComplete resectionMetabolic abnormalitiesBetter outcomesMedial temporal lobe epilepsyResection regionTemporal lobe epilepsyNAA/CrSeizure onset zoneSurgical resectionLobe epilepsySurgical approachSeizure localizationMetabolic dysfunctionInternational LeagueSurgical epilepsyGray matterEpilepsyResectionAbnormalitiesMRSI abnormalitiesOutcome prediction
2008
Temporal distributions of seizure occurrence from various epileptogenic regions
Durazzo TS, Spencer SS, Duckrow RB, Novotny EJ, Spencer DD, Zaveri HP. Temporal distributions of seizure occurrence from various epileptogenic regions. Neurology 2008, 70: 1265-1271. PMID: 18391158, DOI: 10.1212/01.wnl.0000308938.84918.3f.Peer-Reviewed Original ResearchConceptsMesial temporal lobeSeizure occurrencePartial epilepsyTemporal lobeBrain regionsParietal seizuresSeizure distributionNeocortical temporal lobeParietal lobe seizuresTemporal lobe seizuresFrontal lobe seizuresConsecutive adult subjectsCortical brain regionsCircadian rhythmNeocortical temporalSurgical resectionTemporal seizuresIntracranial EEG recordingsEpileptogenic regionSeizuresAdult subjectsEpilepsyEndogenous circadian rhythmLobeEEG recordings