1989
Contributions of cellular leak pathways to net NaHCO3 and NaCl absorption.
Preisig PA, Alpern RJ. Contributions of cellular leak pathways to net NaHCO3 and NaCl absorption. Journal Of Clinical Investigation 1989, 83: 1859-1867. PMID: 2542374, PMCID: PMC303906, DOI: 10.1172/jci114092.Peer-Reviewed Original Research
1987
Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption.
Preisig PA, Ives HE, Cragoe EJ, Alpern RJ, Rector FC. Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption. Journal Of Clinical Investigation 1987, 80: 970-978. PMID: 2888788, PMCID: PMC442334, DOI: 10.1172/jci113190.Peer-Reviewed Original ResearchApical membrane chloride/base exchange in the rat proximal convoluted tubule.
Alpern RJ. Apical membrane chloride/base exchange in the rat proximal convoluted tubule. Journal Of Clinical Investigation 1987, 79: 1026-1030. PMID: 3558814, PMCID: PMC424279, DOI: 10.1172/jci112914.Peer-Reviewed Original Research
1986
Cell pH in the rat proximal convoluted tubule. Regulation by luminal and peritubular pH and sodium concentration.
Alpern RJ, Chambers M. Cell pH in the rat proximal convoluted tubule. Regulation by luminal and peritubular pH and sodium concentration. Journal Of Clinical Investigation 1986, 78: 502-510. PMID: 3016029, PMCID: PMC423587, DOI: 10.1172/jci112602.Peer-Reviewed Original Research
1985
Amiloride inhibition of proximal tubular acidification
Howlin KJ, Alpern RJ, Rector FC. Amiloride inhibition of proximal tubular acidification. American Journal Of Physiology 1985, 248: f773-f778. PMID: 2988347, DOI: 10.1152/ajprenal.1985.248.6.f773.Peer-Reviewed Original ResearchConceptsProximal tubular acidificationLuminal amilorideBicarbonate absorptionX minTubular acidificationM amilorideSodium chloride absorptionLate proximal tubular fluidProximal tubular fluidPerfusion rateProximal acidificationVivo microperfusionTubular fluidKidney cortexChloride absorptionInhibition of acidificationPmol xAmilorideNonspecific inhibitionAmiloride inhibitionGreater inhibitionBrush border membrane vesiclesInhibitionGlucose effluxPotent inhibitor
1983
Flow dependence of proximal tubular bicarbonate absorption
Alpern RJ, Cogan MG, Rector FC. Flow dependence of proximal tubular bicarbonate absorption. American Journal Of Physiology 1983, 245: f478-f484. PMID: 6414312, DOI: 10.1152/ajprenal.1983.245.4.f478.Peer-Reviewed Original ResearchConceptsLuminal bicarbonate concentrationBicarbonate absorptionFlow-dependent increaseFlow-dependent decreaseProximal convoluted tubulesBicarbonate concentrationFlow-induced increaseFlow-dependent changesConvoluted tubulesX minPmol xStimulationProton secretionTubulesPerfusion rateMaximal rateObserved stimulationMin