1984
Bicarbonate-water interactions in the rat proximal convoluted tubule. An effect of volume flux on active proton secretion.
Alpern RJ. Bicarbonate-water interactions in the rat proximal convoluted tubule. An effect of volume flux on active proton secretion. The Journal Of General Physiology 1984, 84: 753-770. PMID: 6096481, PMCID: PMC2228763, DOI: 10.1085/jgp.84.5.753.Peer-Reviewed Original Research
1983
Flow dependence of proximal tubular bicarbonate absorption
Alpern RJ, Cogan MG, Rector FC. Flow dependence of proximal tubular bicarbonate absorption. American Journal Of Physiology 1983, 245: f478-f484. PMID: 6414312, DOI: 10.1152/ajprenal.1983.245.4.f478.Peer-Reviewed Original ResearchConceptsLuminal bicarbonate concentrationBicarbonate absorptionFlow-dependent increaseFlow-dependent decreaseProximal convoluted tubulesBicarbonate concentrationFlow-induced increaseFlow-dependent changesConvoluted tubulesX minPmol xStimulationProton secretionTubulesPerfusion rateMaximal rateObserved stimulationMinEffects of extracellular fluid volume and plasma bicarbonate concentration on proximal acidification in the rat.
Alpern RJ, Cogan MG, Rector FC. Effects of extracellular fluid volume and plasma bicarbonate concentration on proximal acidification in the rat. Journal Of Clinical Investigation 1983, 71: 736-746. PMID: 6826733, PMCID: PMC436924, DOI: 10.1172/jci110821.Peer-Reviewed Original ResearchConceptsNet bicarbonate absorptionExtracellular fluid volumeVolume-expanded ratsLuminal bicarbonate concentrationPlasma bicarbonate concentrationBicarbonate absorptionVolume statusFluid volumeBicarbonate concentrationProton secretionExtracellular fluid volume statusBicarbonate permeabilityFluid volume statusPeritubular bicarbonate concentrationsProximal acidificationHydropenic ratsRatsAcidotic ratsSecretionAbove inhibitionLuminal compositionAlkalosisVolume expansionTubulesMM bicarbonate
1982
Effect of luminal bicarbonate concentration on proximal acidification in the rat
Alpern RJ, Cogan MG, Rector FC. Effect of luminal bicarbonate concentration on proximal acidification in the rat. American Journal Of Physiology 1982, 243: f53-f59. PMID: 7091367, DOI: 10.1152/ajprenal.1982.243.1.f53.Peer-Reviewed Original ResearchConceptsLuminal bicarbonate concentrationBicarbonate absorptionBicarbonate concentrationNet bicarbonate absorptionProximal convoluted tubulesProximal tubular acidificationProton secretionBicarbonate leakProximal acidificationTubular acidificationConvoluted tubulesBicarbonate permeabilitySecretionRats