Mechanism of Distal Acidification: Relevance to Distal RTA
Alpern R. Mechanism of Distal Acidification: Relevance to Distal RTA. 1991, 1184-1188. DOI: 10.1007/978-3-662-35158-1_119.Peer-Reviewed Original ResearchMinimal urinary pHH secretionUrinary pHDistal acidificationLuminal pHDistal Na deliveryPresence of hyperkalemiaCortical collecting tubuleDistal RTAHigher luminal pHTubule functionAcid secretionDistal nephronDisease processK secretionCollecting tubuleSecretionNa deliveryHCO3- exchangerAbnormal leakMinimal gradientH pumpHyperkalemiaAldosteroneMembrane ATP