2013
Chapter 58 Clinical Syndromes of Metabolic Alkalosis
Moe O, Alpern R, Seldin D. Chapter 58 Clinical Syndromes of Metabolic Alkalosis. 2013, 2021-2047. DOI: 10.1016/b978-0-12-381462-3.00058-6.Peer-Reviewed Original ResearchChapter 59 Clinical Syndromes of Metabolic Acidosis
Krapf R, Seldin D, Alpern R. Chapter 59 Clinical Syndromes of Metabolic Acidosis. 2013, 2049-2111. DOI: 10.1016/b978-0-12-381462-3.00059-8.Peer-Reviewed Original ResearchMetabolic acidosisDivalent ion metabolismMaladaptive renal responseUrine anion gapAcute metabolic acidosisNegative nitrogen balanceAcid-base disturbancesBlood buffer capacitySecondary hypocapniaClinical sequelaeRenal responseChronic settingClinical syndromeVentilatory responseBone metabolismBone massAnion gapPrimary decreaseSevere formDiagnostic criteriaBone qualitySecondary decreaseAcidosisElectrolyte changesClinical setting
1991
Dietary NaCl modulates Na(+)-H+ antiporter activity in renal cortical apical membrane vesicles
Moe OW, Tejedor A, Levi M, Seldin DW, Preisig PA, Alpern RJ. Dietary NaCl modulates Na(+)-H+ antiporter activity in renal cortical apical membrane vesicles. American Journal Of Physiology 1991, 260: f130-f137. PMID: 1847012, DOI: 10.1152/ajprenal.1991.260.1.f130.Peer-Reviewed Original ResearchConceptsDietary NaClNaCl reabsorptionSystemic acid-base disturbancesExtracellular fluid volume depletionNaHCO3 reabsorptionExtracellular fluid volume expansionFluid volume depletionHigh-salt dietChronic metabolic alkalosisFluid volume expansionAcridine orange fluorescence methodExtracellular fluid volumeAcid-base disturbancesAntiporter activityDietary protocolChronic alterationsVolume depletionMetabolic alkalosisChronic changesHS dietApical membrane vesiclesLS dietFluid volumeRatsReabsorption