2018
Solid organ transplantation of viral hepatitis C positive donor organs into viral hepatitis C negative recipients
Liapakis A, Formica RN, Levitsky J. Solid organ transplantation of viral hepatitis C positive donor organs into viral hepatitis C negative recipients. Current Opinion In Organ Transplantation 2018, 23: 257-263. PMID: 29432255, DOI: 10.1097/mot.0000000000000504.Peer-Reviewed Original ResearchConceptsViremic donorsHepatitis CWaitlist mortalityHepatitis C viremic donorsEarly trial dataHCV-negative recipientsTransplantation of graftsHepatitis C therapySolid organ transplantsSolid organ transplantationUtilization of graftsFormal clinical trialsNet overall reductionGraft utilizationNonviremic recipientsTransplant recipientsC therapyNegative patientsAntiviral therapyNegative recipientsTransplantation ratesClinical trialsOrgan poolDonor organsOrgan transplantation
2017
Transition probabilities between changing sensitization levels, waitlist activity status and competing-risk kidney transplant outcomes using multi-state modeling
Kulkarni S, Hall I, Formica R, Thiessen C, Stewart D, Gan G, Greene E, Deng Y. Transition probabilities between changing sensitization levels, waitlist activity status and competing-risk kidney transplant outcomes using multi-state modeling. PLOS ONE 2017, 12: e0190277. PMID: 29287087, PMCID: PMC5747475, DOI: 10.1371/journal.pone.0190277.Peer-Reviewed Original ResearchConceptsTransplant probabilityTransplant outcomesActivity statusKidney transplant outcomesKAS implementationPost-KASWaitlist mortalityPatient characteristicsOPTN databaseMulti-state modelingStatistical differenceSensitization levelOutcomesTransplantCohortImpact outcomesCPRAStatus combinationsStatusMortalityWhitesSensitizationPerspectives on the Strengths and Weaknesses of the National Kidney Allocation System
Formica RN. Perspectives on the Strengths and Weaknesses of the National Kidney Allocation System. Clinical Journal Of The American Society Of Nephrology 2017, 12: 2056-2056. PMID: 29162591, PMCID: PMC5718280, DOI: 10.2215/cjn.08640817.Peer-Reviewed Original Research
2016
A critical assessment on kidney allocation systems
Formica RN. A critical assessment on kidney allocation systems. Transplantation Reviews 2016, 31: 61-67. PMID: 27919635, DOI: 10.1016/j.trre.2016.10.002.Peer-Reviewed Original ResearchConceptsKidney allocation systemKidney allocationKidney Donor Profile IndexNew kidney allocation systemDelayed graft functionCold ischemic timeDeceased donor kidneysNumber of transplantsOrgan procurement organizationsGraft functionKidney transplantationIschemic timeDonor kidneysTransplant centersOrgan discard ratesClose monitoringMedical needKidneyProcurement organizationsPatientsTransplantationAllocation systemLife savingSignificant declineProfile indexSimultaneous Liver–Kidney Allocation Policy: A Proposal to Optimize Appropriate Utilization of Scarce Resources
Formica R, Aeder M, Boyle G, Kucheryavaya A, Stewart D, Hirose R, Mulligan D. Simultaneous Liver–Kidney Allocation Policy: A Proposal to Optimize Appropriate Utilization of Scarce Resources. American Journal Of Transplantation 2016, 16: 758-766. PMID: 26603142, DOI: 10.1111/ajt.13631.Peer-Reviewed Original ResearchConceptsMayo End-Stage Liver Disease (MELD) scoreEnd-stage liver disease (MELD) scoreSimultaneous liver-kidney transplantKidney Donor Profile IndexConcurrent kidney transplantsLiver-kidney transplantLiver Disease scoreMedical Eligibility CriteriaLiver allocation policyOPTN Final RulePediatric recipientsKidney transplantRenal functionRenal insufficiencyUnited NetworkLiver candidatesTransplant communityDisease scoreOrgan donorsEligibility criteriaOrgan procurementTransplantation NetworkFinal ruleKidney allocationYoung adults
2015
Association Between Organ Procurement Organization Social Network Centrality and Kidney Discard and Transplant Outcomes
Butala NM, King MD, Reitsma W, Formica RN, Abt PL, Reese PP, Parikh CR. Association Between Organ Procurement Organization Social Network Centrality and Kidney Discard and Transplant Outcomes. Transplantation 2015, 99: 2617-2624. PMID: 26102610, PMCID: PMC4668206, DOI: 10.1097/tp.0000000000000773.Peer-Reviewed Original ResearchConceptsKidney volumeKidney Donor Risk IndexLower kidney volumesDelayed graft functionDonor risk indexKidney transplant waitlistCold ischemia timeDeceased donor kidneysHigher kidney volumeGraft functionGraft lossTransplant recipientsOrgan acceptanceTransplant outcomesDonor kidneysPrimary outcomeWaitlist timeRecipient outcomesScientific RegistryPrimary exposureTransplant waitlistKidney discardMultivariable regressionTransplant NetworkKidney
2014
New National Allocation Policy for Deceased Donor Kidneys in the United States and Possible Effect on Patient Outcomes
Israni AK, Salkowski N, Gustafson S, Snyder JJ, Friedewald JJ, Formica RN, Wang X, Shteyn E, Cherikh W, Stewart D, Samana CJ, Chung A, Hart A, Kasiske BL. New National Allocation Policy for Deceased Donor Kidneys in the United States and Possible Effect on Patient Outcomes. Journal Of The American Society Of Nephrology 2014, 25: 1842-1848. PMID: 24833128, PMCID: PMC4116061, DOI: 10.1681/asn.2013070784.Peer-Reviewed Original ResearchConceptsPost-transplant survivalKidney Donor Profile IndexKidney allocation policyBetter post-transplant survivalOverall post-transplant survivalBlood type A2Panel reactive antibodyDeceased donor kidneysBlood type B candidatesNational allocation policyCurrent allocation policyBlood type BRace/ethnicityA2B kidneysKDPI scoreDialysis initiationDonor kidneysDonor factorsDistribution of kidneysPatient outcomesOrgan procurementTransplantation NetworkKidneyKidney allocationTransplant
2013
The Kidney Allocation System
Friedewald JJ, Samana CJ, Kasiske BL, Israni AK, Stewart D, Cherikh W, Formica RN. The Kidney Allocation System. Surgical Clinics Of North America 2013, 93: 1395-1406. PMID: 24206858, DOI: 10.1016/j.suc.2013.08.007.Peer-Reviewed Original Research
2012
A One-Day Centralized Work-up for Kidney Transplant Recipient Candidates: A Quality Improvement Report
Formica RN, Barrantes F, Asch WS, Bia MJ, Coca S, Kalyesubula R, McCloskey B, Leary T, Arvelakis A, Kulkarni S. A One-Day Centralized Work-up for Kidney Transplant Recipient Candidates: A Quality Improvement Report. American Journal Of Kidney Diseases 2012, 60: 288-294. PMID: 22571868, DOI: 10.1053/j.ajkd.2012.04.008.Peer-Reviewed Original ResearchConceptsKidney transplantImprovement reportMultivariable Cox proportional hazards modelsCox proportional hazards modelKidney transplant candidacyMinimal listing criteriaGroup of patientsUniversity-based hospitalQuality improvement reportProportional hazards modelTransplant candidacyTransplant evaluationUNOS waitlistWaitlist placementTransplant centersComorbid conditionsMedian timeMultivariable analysisTransplant practitionersDialysis exposureFunctional statusWait listHazards modelPatientsRecipient candidates
2010
Accepting a donor kidney: an evaluation of patients’ and transplant surgeons’ priorities
Solomon DA, Rabidou N, Kulkarni S, Formica R, Fraenkel L. Accepting a donor kidney: an evaluation of patients’ and transplant surgeons’ priorities. Clinical Transplantation 2010, 25: 786-793. PMID: 20964716, PMCID: PMC4846340, DOI: 10.1111/j.1399-0012.2010.01342.x.Peer-Reviewed Original ResearchConceptsKidney qualityDonor kidneysTransplant surgeonsEvaluation of patientsMann-Whitney U testTransplant outcomesPatient characteristicsSpearman correlation coefficientPatient prioritiesWaiting listPatientsAvailable kidneysClinical practiceSurgeon rankingsKidneyU testSurgeonsCategorical variablesPatient autonomyComputer surveyCorrelation coefficientTransplantationFactorsGreat value